PMID: Zhongguo Zhong Yao Za Zhi. 2019 Jun ;44(11):2348-2352. PMID: 31359662 Abstract Title: [Ginsenoside Rg_1 induces leukemia stem cell senescence via SIRT1/TSC_2 signal axis]. Abstract: The aim of this paper was to investigate the effect of SIRT1/TSC_2 signal axis on leukemia stem cell senescence induced by ginsenoside Rg_1. CD34~+CD38~- leukemia stem cells(CD34~+CD38~-LSCs) was isolated by …
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Protective effects of ginsenoside Rb1 on H2O2-induced oxidative injury in human endothelial cell line.
PMID: Int J Immunopathol Pharmacol. 2019 Jan-Dec;33:2058738419866021. PMID: 31359794 Abstract Title: Protective effects of ginsenoside Rb1 on HO-induced oxidative injury in human endothelial cell line (EA.hy926) via miR-210. Abstract: Ginsenoside Rb1 (Rb1) possesses a cardioprotective effect via mediating microRNAs (miRs), while it is unexplored whether miR-210 is regulated by Rb1 in response to oxidative stress. …
Ginsenoside compound K ameliorates Alzheimer’s disease in HT22 cells by adjusting energy metabolism.
PMID: Mol Biol Rep. 2019 Jul 30. Epub 2019 Jul 30. PMID: 31364016 Abstract Title: Ginsenoside compound K ameliorates Alzheimer's disease in HT22 cells by adjusting energy metabolism. Abstract: Energy metabolism disorders have been shown to exert detrimental effects on the pathology of Alzheimer's disease (AD). The ginsenoside compound K (CK), a major intestinal metabolite …
Ginsenoside Rg1 ameliorates cardiac oxidative stress and inflammation in streptozotocin-induced diabetic rats.
PMID: Diabetes Metab Syndr Obes. 2019 ;12:1091-1103. Epub 2019 Jul 10. PMID: 31372019 Abstract Title: Ginsenoside Rg1 ameliorates cardiac oxidative stress and inflammation in streptozotocin-induced diabetic rats. Abstract: Ginsenoside Rg1 (GS Rg1), as an important active substance of Panax ginseng, has been proven to have elaborate cardioprotective effects. The purpose of this study was to …
WeToo: Medical Assault and Battery
The latest Canadian study finds that young children born to mothers living in fluoridated communities are at risk of having lower IQs
Ginsenoside Rg1 attenuates chronic unpredictable mild stress-induced depressive-like effects.
PMID: Neuroreport. 2019 Sep 4 ;30(13):893-900. PMID: 31373969 Abstract Title: Ginsenoside Rg1 attenuates chronic unpredictable mild stress-induced depressive-like effect via regulating NF-κB/NLRP3 pathway in rats. Abstract: Ginsenoside (GS Rg1), which has neuroprotection and anti-inflammation activities, is the main active ingredient of Radix Ginseng. However, its antidepressant-like effect in rats remains unclear. Our study was conducted …
Ginsenoside Rg3 has stereoselective anti-cancer effects in the AQP1 high-expressing cell line MDA-MB-231.
PMID: Pharmaceuticals (Basel). 2019 Aug 1 ;12(3). Epub 2019 Aug 1. PMID: 31374984 Abstract Title: Stereoselective Anti-Cancer Activities of Ginsenoside Rg3 on Triple Negative Breast Cancer Cell Models. Abstract: Ginsenoside Rg3 (Rg3) has two epimers, 20(S)-ginsenoside Rg3 (SRg3) and 20(R)-ginsenoside Rg3 (RRg3), and while Rg3 itself has been reported to have anti-cancer properties, few studies …
Ginsenoside Rd inhibits IL-1β-induced inflammation and degradation of intervertebral disc chondrocytes.
PMID: Braz J Med Biol Res. 2019 ;52(9):e8525. Epub 2019 Aug 12. PMID: 31411316 Abstract Title: Ginsenoside Rd inhibits IL-1β-induced inflammation and degradation of intervertebral disc chondrocytes by increasing IL1RAP ubiquitination. Abstract: Many compounds of ginsenosides show anti-inflammatory properties. However, their anti-inflammatory effects in intervertebral chondrocytes in the presence of inflammatory factors have never been …
Ginsenoside GRb1 could reduce the cell apoptosis induced by spinal cord ischemia-reperfusion through inhibiting oxidative stress.
PMID: J Orthop Surg Res. 2019 Aug 14 ;14(1):259. Epub 2019 Aug 14. PMID: 31412899 Abstract Title: Effects of ginsenoside Rb1 on spinal cord ischemia-reperfusion injury in rats. Abstract: BACKGROUND: The aim of this study was to evaluate the effects of different doses of ginsenoside Rb1 (GRb1) pretreatment on spinal cord ischemia-reperfusion (SCII) in rats …
Ginsenoside Rd reverses cisplatin resistance in non-small-cell lung cancer A549 cells.
PMID: Anticancer Drugs. 2019 Sep ;30(8):838-845. PMID: 31415285 Abstract Title: Ginsenoside Rd reverses cisplatin resistance in non-small-cell lung cancer A549 cells by downregulating the nuclear factor erythroid 2-related factor 2 pathway. Abstract: Clinical drug resistance to platinum-based chemotherapy is considered a major impediment in the successful treatment of non-small-cell lung cancer (NSCLC). The nuclear factor …
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