PMID: Cochrane Database Syst Rev. 2012 Aug 15(8):CD004879. Epub 2012 Aug 15. PMID: 22895945 Abstract Title: Vaccines for preventing influenza in healthy children. Abstract: BACKGROUND: The consequences of influenza in children and adults are mainly absenteeism from school and work. However, the risk of complications is greatest in children and people over 65 years of …
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Crocin attenuates isoprenaline-induced myocardial fibrosis.
PMID: Naunyn Schmiedebergs Arch Pharmacol. 2019 Aug 7. Epub 2019 Aug 7. PMID: 31392383 Abstract Title: Crocin attenuates isoprenaline-induced myocardial fibrosis by targeting TLR4/NF-κB signaling: connecting oxidative stress, inflammation, and apoptosis. Abstract: Crocin is isolated from saffron and has multiple activities. There are many reports on its beneficial effects for cardiovascular disease, but crocin's effects …
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Crocin attenuates metabolic syndrome-induced osteoporosis.
PMID: J Food Biochem. 2019 Jul ;43(7):e12895. Epub 2019 May 15. PMID: 31353703 Abstract Title: Crocin attenuates metabolic syndrome-induced osteoporosis in rats. Abstract: In the current study, anti-osteoporotic activities of crocin were evaluated in a rat model of metabolic syndrome-induced osteoporosis. Metabolic syndrome was confirmed by increased body weight gain, increased fasting blood glucose, hyperinsulinemia, …
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A review of the therapeutic effects of crocin in autoimmune diseases.
PMID: Biofactors. 2019 Aug 20. Epub 2019 Aug 20. PMID: 31430413 Abstract Title: Therapeutic effects of Crocin in autoimmune diseases: A review. Abstract: The immune system when acts against selfmolecules results in an imbalance in immunologic tolerance leading to the development of several autoimmune diseases (ADs) such as rheumatoid arthritis, asthma, ulcerative colitis, type 1 …
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Saffron extract may exert a protective effect in glaucomatous pathology.
PMID: Int J Mol Sci. 2019 Aug 22 ;20(17). Epub 2019 Aug 22. PMID: 31443568 Abstract Title: Neuroprotective and Anti-Inflammatory Effects of a Hydrophilic Saffron Extract in a Model of Glaucoma. Abstract: Glaucoma is a neurodegenerative disease characterized by the loss of retinal ganglion cells (RGCs). An increase in the intraocular pressure is the principal …
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This study provided an insight into yet another antimicrobial mechanism of allicin.
PMID: J Med Microbiol. 2019 Apr ;68(4):667-677. Epub 2019 Mar 19. PMID: 30888314 Abstract Title: Allicin causes fragmentation of the peptidoglycan coat in Staphylococcus aureus by effecting synthesis and aiding hydrolysis: a determination by MALDI-TOF mass spectrometry on whole cells. Abstract: PURPOSE: To determine the effect of allicin on Staphylococcus aureus cell wall peptidoglycans by …
Allicin may be useful in preventing cisplatin-induced ototoxicity.
PMID: ORL J Otorhinolaryngol Relat Spec. 2019 Jul 24:1-13. Epub 2019 Jul 24. PMID: 31340214 Abstract Title: Allicin Protects against Cisplatin-Induced Stria Vascularis Damage: Possible Relation to Inhibition of Caspase-3 and PARP-1-AIF-Mediated Apoptotic Pathways. Abstract: Cisplatin is an anti-cancer drug that causes oxotoxic side effects such as impairment of inner ear function and hearing loss. …
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Allicin can protect rats against myocardial ischemia reperfusion injury by suppressing inflammation and oxidative stress.
PMID: Transplant Proc. 2019 Jul – Aug;51(6):2060-2065. PMID: 31399184 Abstract Title: Allicin Attenuates Myocardial Ischemia Reperfusion Injury in Rats by Inhibition of Inflammation and Oxidative Stress. Abstract: OBJECTIVE: To explore the protective effect and underlying mechanism of allicin (ALC) on myocardial ischemia reperfusion (MI/R) injury in rats.METHODS: The model of MI/R injury in rats was …
Eriobotrya japonica leaf extract potentially provides cardio-protective effects against hypertension-induced cardiac apoptosis and fibrosis.
PMID: Int J Mol Sci. 2018 May 31 ;19(6). Epub 2018 May 31. PMID: 29857545 Abstract Title: Anti-Apoptosis and Anti-Fibrosis Effects ofin Spontaneously Hypertensive Rat Hearts. Abstract: Myocardial apoptosis and fibrosis represent important contributing factors for development of hypertension-induced heart failure. The present study aims to investigate the potential effects ofleaf extract (EJLE) against hypertension-induced …
Eriobotrya leaf extract and its fractions have a hepatoprotective effect against carbon tetrachloride-induced hepatotoxicity.
PMID: Evid Based Complement Alternat Med. 2018 ;2018:3782768. Epub 2018 Dec 16. PMID: 30643530 Abstract Title: Hepatoprotective Effect ofLeaf Extract and Its Various Fractions against Carbon Tetra Chloride Induced Hepatotoxicity in Rats. Abstract: is traditionally used as an antipyretic, digestive, and diuretic agent. Its flowers possess free radical-scavenging, antioxidative, and hepatoprotective effects. We investigated the …
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