Identification and microbial production of the raspberry phenol salidroside that is active against Huntington’s disease.

PMID:  Plant Physiol. 2019 03 ;179(3):969-985. Epub 2018 Nov 5. PMID: 30397021 Abstract Title:  Identification and Microbial Production of the Raspberry Phenol Salidroside that Is Active against Huntington's Disease. Abstract:  Edible berries are considered to be among nature's treasure chests as they contain a large number of (poly)phenols with potentially health-promoting properties. However, as berries …

This study demonstrates that mercury amalgams have not been proven to be safe in children.

PMID:  Altern Ther Health Med. 2006 Jul-Aug;12(4):16-7. PMID: 16862738 Abstract Title:  Are mercury amalgam fillings safe for children? An evaluation of recent research results. Abstract:  Two recent clinical trials on the safety of amalgam fillings in children found no evidence of harmful effects from mercury-containing dental fillings after following children for 5-7 years. This review …

Wild blackberry extracts demonstrated a potential beneficial effect on the control or management of type-2 diabetes mellitus.

PMID:  Food Chem Toxicol. 2019 Jan ;123:443-452. Epub 2018 Nov 5. PMID: 30408537 Abstract Title:  Evaluation of Rubus grandifolius L. (wild blackberries) activities targeting management of type-2 diabetes and obesity using in vitro models. Abstract:  Rubus grandifolius Lowe (wild blackberries) is an endemic species from Madeira Archipelago (Portugal) used in folk medicine for alleviating diabetic …

Thimerosal may have a higher affinity for brain tissue compared to inorganic mercury.

PMID:  J Appl Toxicol. 2006 Nov-Dec;26(6):536-9. PMID: 17080402 Abstract Title:  Comparison of organic and inorganic mercury distribution in suckling rat. Abstract:  Thiomersal is used as a preservative in vaccines given to small children. The metabolic product of thiomersal is ethylmercury and its distribution and kinetics are still not known, especially at this early age. The …

Boron alleviates gentamicin-induced nephrotoxicity in rats.

PMID:  Biol Trace Elem Res. 2019 Aug 24. Epub 2019 Aug 24. PMID: 31446563 Abstract Title:  Boron, a Trace Mineral, Alleviates Gentamicin-Induced Nephrotoxicity in Rats. Abstract:  The present study was considered to assess the protective effects of boron (B) on gentamicin-induced oxidative stress, proinflammatory cytokines, and histopathological changes in rat kidneys. Rats were split into …

Aluminum affects neural phenotype determination of embryonic neural progenitor cells.

PMID:  Arch Toxicol. 2019 Jul 30. Epub 2019 Jul 30. PMID: 31363819 Abstract Title:  Aluminum affects neural phenotype determination of embryonic neural progenitor cells. Abstract:  Aluminum (Al) is a neurotoxin and is associated with the etiology of neurodegenerative diseases, such as Alzheimer's disease (AD). The Al-free ion (Al) is the biologically reactive and toxic form. …

Thimerosal impacts nerve growth factor signaling at levels lower than those responsible for cell death.

PMID:  Toxicol Sci. 2005 Jul ;86(1):132-40. Epub 2005 Apr 20. PMID: 15843506 Abstract Title:  Effects of thimerosal on NGF signal transduction and cell death in neuroblastoma cells. Abstract:  Signaling through neurotrophic receptors is necessary for differentiation and survival of the developing nervous system. The present study examined the effects of the organic mercury compound thimerosal …

Red raspberry extract protects the skin against UVB-induced damage with antioxidative and anti-inflammatory properties.

PMID:  Oxid Med Cell Longev. 2019 ;2019:9529676. Epub 2019 Jan 6. PMID: 30723535 Abstract Title:  Red Raspberry Extract Protects the Skin against UVB-Induced Damage with Antioxidative and Anti-inflammatory Properties. Abstract:  Extensive exposure to UVB (280-320 nm) is the major risk responsible for various skin injuries. Numerous reports have shown that natural products could demonstrate photochemopreventive efficacy …

Mercury is an environmental risk factor for cardiovascular diseases through calcium-dependent mechanisms.

PMID:  Int J Toxicol. 2009 May-Jun;28(3):190-206. PMID: 19546257 Abstract Title:  Calcium and calmodulin regulate mercury-induced phospholipase D activation in vascular endothelial cells. Abstract:  Earlier, we reported that mercury, the environmental risk factor for cardiovascular diseases, activates vascular endothelial cell (EC) phospholipase D (PLD). Here, we report the novel and significant finding that calcium and calmodulin …

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