Carnosol activates Nrf2 leading to sestrin 2 induction in colon cells.

PMID:  Integr Mol Med. 2018 Aug ;5(4). Epub 2018 Aug 15. PMID: 30972223 Abstract Title:  Carnosol, a dietary diterpene from rosemary () activates Nrf2 leading to sestrin 2 induction in colon cells. Abstract:  Background: Rosemary is abundant with phytochemicals and has recently been approved as an antioxidant food preservative in the European Union. The safety …

Rosmarinus officinalis L.: an update review of its phytochemistry and biological activity.

PMID:  Future Sci OA. 2018 Apr ;4(4):FSO283. Epub 2018 Feb 1. PMID: 29682318 Abstract Title:  L.: an update review of its phytochemistry and biological activity. Abstract:  The worldwide interest in the use of medicinal plants has been growing, and its beneficial effects being rediscovered for the development of new drugs. Based on their vast ethnopharmacological …

This study shows no risk of glioma associated with either short or medium term cell phone use. This is in agreement with some but not all studies.

PMID:  BMJ. 2006 Apr 15 ;332(7546):883-7. Epub 2006 Jan 20. PMID: 16428250 Abstract Title:  Mobile phone use and risk of glioma in adults: case-control study. Abstract:  OBJECTIVE: To investigate the risk of glioma in adults in relation to mobile phone use.DESIGN: Population based case-control study with collection of personal interview data.SETTING: Five areas of the …

Are Cannabidiol (CBD) Products Legal?

On a daily basis, we are asked, are CBD products really legal? And the answer is, yes! For decades, growing hemp was prohibited until the 2014 Farm Bill made state-based hemp research programs legal. On December 12, the United States Congress voted to pass the Agriculture Improvement Act of 2018, more commonly referred to as the Farm …

Cardamonin represses proliferation, invasion, and causes apoptosis in prostate cancer.

PMID:  Apoptosis. 2017 01 ;22(1):158-168. PMID: 27900636 Abstract Title:  Cardamonin represses proliferation, invasion, and causes apoptosis through the modulation of signal transducer and activator of transcription 3 pathway in prostate cancer. Abstract:  The pleiotropic transcription factor, signal transducer and activator of transcription 3 (STAT3) is often aberrantly activated in a wide variety of cancers and …

Cardamonin attenuates hyperalgesia and allodynia in a mouse model of chronic constriction injury-induced neuropathic pain.

PMID:  Eur J Pharmacol. 2017 Feb 5 ;796:32-38. Epub 2016 Dec 15. PMID: 27988285 Abstract Title:  Cardamonin attenuates hyperalgesia and allodynia in a mouse model of chronic constriction injury-induced neuropathic pain: Possible involvement of the opioid system. Abstract:  Neuropathic pain arises from the injury of nervous system. The condition is extremely difficult to be treated …

Activation of Nrf2-driven antioxidant enzymes by cardamonin confers neuroprotection of PC12 cells against oxidative damage.

PMID:  Food Funct. 2017 Mar 22 ;8(3):997-1007. PMID: 28271112 Abstract Title:  Activation of Nrf2-driven antioxidant enzymes by cardamonin confers neuroprotection of PC12 cells against oxidative damage. Abstract:  Oxidative stress represents a disorder of the redox equilibrium between the production of free radicals and the capability of cells to eliminate them. As subversion of this redox …

Protective effect of cardamonin against acetic acid-induced ulcerative colitis in rats.

PMID:  Pharmacol Rep. 2017 Apr ;69(2):268-275. Epub 2016 Nov 9. PMID: 28129600 Abstract Title:  Protective effect of cardamonin against acetic acid-induced ulcerative colitis in rats. Abstract:  BACKGROUND: Ulcerative colitis (UC) is an inflammatory bowel disease with significant morbidity. Cardamonin is a natural chalcone derivative with considerable anti-inflammatory activity. Herein, the potential protective effect of cardamonin …

Cardamonin could be a promising strategy in patients with hepatic Ischemia reperfusion injury.

PMID:  Eur J Pharmacol. 2017 Nov 15 ;815:446-453. Epub 2017 Sep 28. PMID: 28966130 Abstract Title:  Effect of cardamonin on hepatic ischemia reperfusion induced in rats: Role of nitric oxide. Abstract:  Ischemia reperfusion (I/R) injury is a cellular damage in a hypoxic organ following the restoration of oxygen delivery. It may occur during organ transplantation, …

Design a site like this with WordPress.com
Get started