This study is a diagnostic test that seeks to test the radical pair hypothesis.

PMID:  J Am Chem Soc. 2004 Jul 7 ;126(26):8102-3. PMID: 15225036 Abstract Title:  Radio frequency magnetic field effects on a radical recombination reaction: a diagnostic test for the radical pair mechanism. Abstract:  The photoinduced electron-transfer reaction of chrysene with isomers of dicyanobenzene is used to demonstrate the sensitivity of a radical recombination reaction to the …

Cardamonin inhibits colonic neoplasia through modulation of MicroRNA expression.

PMID:  Sci Rep. 2017 10 24 ;7(1):13945. Epub 2017 Oct 24. PMID: 29066742 Abstract Title:  Cardamonin inhibits colonic neoplasia through modulation of MicroRNA expression. Abstract:  Colorectal cancer is currently the third leading cause of cancer related deaths. There is considerable interest in using dietary intervention strategies to prevent chronic diseases including cancer. Cardamonin is a …

These results do not indicate an association between measured exposure to RF EMF and chronic well-being in children and adolescents.

PMID:  Environ Int. 2011 Jan ;37(1):26-30. PMID: 20619895 Abstract Title:  The impact of exposure to radio frequency electromagnetic fields on chronic well-being in young people–a cross-sectional study based on personal dosimetry. Abstract:  A possible influence of radio frequency electromagnetic field (RF EMF) exposure on health outcomes was investigated in various studies. The main problem of …

Modification in the quantity, composition, and peroxidation of sebaceous lipid are believed to play a signficant role in acne pathogenesis.

PMID:  Mediators Inflamm. 2010 ;2010. Epub 2010 Aug 25. PMID: 20871834 Abstract Title:  Lipid mediators in acne. Abstract:  Multiple factors are involved in acne pathogenesis, and sebum secretion is one of the main ones. The role sebum plays in acne development has not been completely elucidated yet; however, increasing amounts of data seem to confirm …

Thymic stromal lymphopoietin downregulation may contribute to the inflammation in rosacea which is influenced by sebum lipids.

PMID:  J Invest Dermatol. 2017 05 ;137(5):1114-1125. Epub 2017 Jan 25. PMID: 28131815 Abstract Title:  Sebaceous Gland-Rich Skin Is Characterized by TSLP Expression and Distinct Immune Surveillance Which Is Disturbed in Rosacea. Abstract:  The microbial community exhibits remarkable diversity on topographically distinct skin regions, which may be accompanied by differences in skin immune characteristics. Our aim …

Cardamonin is a potential candidate for controlling inflammation during primary Sjögren’s syndrome.

PMID:  Immunopharmacol Immunotoxicol. 2018 Apr ;40(2):126-133. Epub 2018 Jan 5. PMID: 29303022 Abstract Title:  Cardamonin inhibits pro-inflammatory cytokine production and suppresses NO pathway in PBMCs from patients with primary Sjögren's syndrome. Abstract:  Primary Sjögren's syndrome (pSS) is a systemic autoimmune disorder with a complex pathophysiology primarily affecting exocrine glands, leading to compromised secretory function. Recent …

Sebum lipid composition determines whether sebum exerts an anti-inflammatory, antimicrobial or pro-inflammatory action.

PMID:  Dermatoendocrinol. 2017 ;9(1):e1375636. Epub 2017 Oct 17. PMID: 29484100 Abstract Title:  Sebaceous-immunobiology is orchestrated by sebum lipids. Abstract:  The major role of sebaceous glands in mammals is to produce sebum, which coats the epidermis and the hair providing waterproofing, thermoregulation and photoprotection. However, as the need for these functions decreased along the evolutionary changes …

Cardamonin enhances the anti-proliferative effect of cisplatin on ovarian cancer.

PMID:  Oncol Lett. 2018 Mar ;15(3):3991-3997. Epub 2018 Jan 8. PMID: 29456744 Abstract Title:  Cardamonin enhances the anti-proliferative effect of cisplatin on ovarian cancer. Abstract:  The mammalian target of rapamycin (mTOR) is well-known as a promising therapeutic target in various cancer cells. mTOR activation decreases the sensitivity of ovarian cancer to cisplatin. Cardamonin inhibits the …

Anti-inflammatory effects of cardamonin in ovarian cancer cells are mediated via mTOR suppression.

PMID:  Planta Med. 2018 Nov ;84(16):1183-1190. Epub 2018 May 17. PMID: 29772587 Abstract Title:  Anti-inflammatory Effects of Cardamonin in Ovarian Cancer Cells Are Mediated via mTOR Suppression. Abstract:  Cardamonin exhibits a variety of pharmacological activities including anti-inflammatory and antitumor, which are correlated with the inhibition of nuclear factor-kappaB and the mammalian target of rapamycin, respectively. …

Cardamonin reduces chemotherapy resistance of colon cancer cells.

PMID:  Oncol Lett. 2018 Jun ;15(6):9641-9646. Epub 2018 Apr 26. PMID: 29928339 Abstract Title:  Cardamonin reduces chemotherapy resistance of colon cancer cells via the TSP50/NF-κB pathway. Abstract:  It has previously been reported that cardamonin is able to regulate glycometabolism and vasodilation whilst also exhibiting anti-inflammatory and antitumor properties. The antitumor effect of cardamonin is multifaceted, …

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