Category Archives: Uncategorized

PMID:  Front Pharmacol. 2018 ;9:1268. Epub 2018 Nov 21. PMID: 30524274 Abstract Title:  Nephroprotective Effects of Benzyl Isothiocyanate and Resveratrol Against Cisplatin-Induced Oxidative Stress and Inflammation. Abstract:  This study was performed to compare the nephroprotective effects of benzyl isothiocyanate (BITC) and resveratrol (RES) and investigate the nephroprotective efficacy of their combination against cisplatin-induced acute renal …

Continue reading “Nephroprotective effects of benzyl isothiocyanate and resveratrol against cisplatin-induced oxidative stress and inflammation.”

PMID:  Cancer Prev Res (Phila). 2019 Mar ;12(3):125-134. Epub 2019 Feb 5. PMID: 30723175 Abstract Title:  Role of Krüppel-like Factor 4-p21Axis in Breast Cancer Stem-like Cell Inhibition by Benzyl Isothiocyanate. Abstract:  Cancer chemoprevention by benzyl isothiocyanate (BITC), which is derived from cruciferous vegetables like garden cress, in a transgenic mouse model of breast cancer is …

Continue reading “Breast cancer chemoprevention by benzyl isothiocyanate may be augmented with a combination regimen involving an inhibitor of KLF4.”

PMID:  J Ethnopharmacol. 2019 Oct 5 ;242:112039. Epub 2019 Jun 26. PMID: 31252093 Abstract Title:  Antihypertensive activity of Petroselinum crispum through inhibition of vascular calcium channels in rats. Abstract:  ETHNOPHARMACOLOGICAL RELEVANCE: Parsley (Petroselinum crispum; P. crispum) is among the popular aromatic vegetables and a part of the daily diet in the Mediterranean area. This plant …

Continue reading “Antihypertensive activity of Petroselinum crispum through inhibition of vascular calcium channels in rats.”

PMID:  Cancer. 2008 Oct 1 ;113(7 Suppl):1953-68. PMID: 18798534 Abstract Title:  Brain tumor epidemiology: consensus from the Brain Tumor Epidemiology Consortium. Abstract:  Epidemiologists in the Brain Tumor Epidemiology Consortium (BTEC) have prioritized areas for further research. Although many risk factors have been examined over the past several decades, there are few consistent findings, possibly because …

Continue reading “The possible influence of currently acceptable low-level RF exposures on carcinogenesis has been suggested by some studies and warrants further investigation.”

PMID:  Saudi J Biol Sci. 2019 Jul ;26(5):1089-1092. Epub 2018 May 3. PMID: 31303845 Abstract Title:  Chemical composition and antimicrobial, antioxidant, and anti-inflammatory activities ofseed oil. Abstract:  (garden cress) seed oil was examined for its antimicrobial, antioxidant, and anti-inflammatory activities. The oil was obtained by hydrodistillation, where gas chromatography coupled with mass spectrometry that utilized …

Continue reading “Chemical composition and antimicrobial, antioxidant, and anti-inflammatory activities of Lepidium sativum seed oil.”

PMID:  J Integr Med. 2019 May ;17(3):221-228. Epub 2019 Mar 23. PMID: 30940420 Abstract Title:  Induction of apoptosis in leukemic cells by the alkaloid extract of garden cress (Lepidium sativum L.). Abstract:  OBJECTIVE: Garden cress (Lepidium sativum L.) is an important herb in traditional medicine used to improve production of breast milk in women and …

Continue reading “Induction of apoptosis in leukemic cells by the alkaloid extract of garden cress.”

PMID:  Int J Oncol. 2019 Jun ;54(6):2106-2116. Epub 2019 Mar 26. PMID: 30942430 Abstract Title:  Benzyl isothiocyanate suppresses IGF1R, FGFR3 and mTOR expression by upregulation of miR-99a-5p in human bladder cancer cells. Abstract:  Benzyl isothiocyanate (BITC) is known for its pharmacological properties against malignant neoplasm, including bladder cancer (BC). The current study investigated microRNAs (miRNA or …

Continue reading “Benzyl isothiocyanate suppresses IGF1R, FGFR3 and mTOR expression by upregulation of miR-99a-5p in human bladder cancer cells.”

PMID:  Braz J Med Biol Res. 2019 Apr 8 ;52(4):e8409. Epub 2019 Apr 8. PMID: 30970087 Abstract Title:  Benzyl isothiocyanate inhibits invasion and induces apoptosis via reducing S100A4 expression and increases PUMA expression in oral squamous cell carcinoma cells. Abstract:  Benzyl isothiocyanate (BITC) has been shown to inhibit invasion and induce apoptosis of various types …

Continue reading “Benzyl isothiocyanate is a potential therapeutic approach for oral squamous cell carcinoma.”

PMID:  Sci Rep. 2019 Jun 20 ;9(1):8866. Epub 2019 Jun 20. PMID: 31222108 Abstract Title:  Yeast screening system reveals the inhibitory mechanism of cancer cell proliferation by benzyl isothiocyanate through down-regulation of Mis12. Abstract:  Benzyl isothiocyanate (BITC) is a naturally-occurring isothiocyanate derived from cruciferous vegetables. BITC has been reported to inhibit the proliferation of various …

Continue reading “Yeast screening system reveals the inhibitory mechanism of cancer cell proliferation by benzyl isothiocyanate through down-regulation of Mis12.”

PMID:  J Agric Food Chem. 2019 Jun 26 ;67(25):7136-7146. Epub 2019 Jun 18. PMID: 31240929 Abstract Title:  Benzyl Isothiocyanate and Phenethyl Isothiocyanate Inhibit Adipogenesis and Hepatosteatosis in Mice with Obesity Induced by a High-Fat Diet. Abstract:  Benzyl isothiocyanate (BITC) and phenethyl isothiocyanate (PEITC) are organosulfur phytochemicals rich in cruciferous vegetables. We investigated the antiobesity and …

Continue reading “These findings indicate that benzyl isothiocyanate and phenethyl isothiocyanate ameliorate high fat diet-induced obesity and fatty liver.”