PMID: Food Funct. 2019 Jul 23. Epub 2019 Jul 23. PMID: 31334539 Abstract Title: Acute treatment with Mangifera indica L. leaf extract attenuates liver inflammation in rats fed a cafeteria diet. Abstract: This study investigates the acute anti-inflammatory activity of Mangifera indica L. leaf extract and mangiferin in the liver of rats fed a cafeteria …
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Mangiferin suppresses allergic asthma symptoms by decreased Th9 and Th17 responses and increased Treg response.
PMID: Mol Immunol. 2019 Aug 3 ;114:233-242. Epub 2019 Aug 3. PMID: 31386980 Abstract Title: Mangiferin suppresses allergic asthma symptoms by decreased Th9 and Th17 responses and increased Treg response. Abstract: Mangiferin is the major bioactive ingredient in the leaves of Mangifera indica L., Aqueous extract of such leaves have been traditionally used as an …
These findings suggest a significant correlation between high hs-CRP levels and depression in younger adults.
PMID: Psychoneuroendocrinology. 2019 Jul 30 ;109:104397. Epub 2019 Jul 30. PMID: 31377557 Abstract Title: Elevated hs-CRP level is associated with depression in younger adults: Results from the Korean National Health and Nutrition Examination Survey (KNHANES 2016). Abstract: INTRODUCTION: Reports on the association between the level of circulating high-sensitivity C-reactive protein (hs-CRP) and depression have been …
Investigation of the neuroprotective effects of thymoquinone on rat spinal cord exposed to 900 MHz electromagnetic field.
PMID: J Chem Neuroanat. 2019 Jun 19 ;100:101657. Epub 2019 Jun 19. PMID: 31228532 Abstract Title: Investigation of the neuroprotective effects of thymoquinone on rat spinal cord exposed to 900 MHz electromagnetic field. Abstract: Exposure to electromagnetic field in long-term use of cell phones has increased concerns about serious health problems. Our aim was to …
Thymoquinone suppresses the proliferation of renal cell carcinoma cells via reactive oxygen species-induced apoptosis and reduces cell stemness.
PMID: Environ Toxicol. 2019 Jul 12. Epub 2019 Jul 12. PMID: 31298468 Abstract Title: Thymoquinone suppresses the proliferation of renal cell carcinoma cells via reactive oxygen species-induced apoptosis and reduces cell stemness. Abstract: Thymoquinone is a phytochemical compound isolated from Nigella sativa and has various biological effects, including anti-inflammation, antioxidation, and anticancer. Here, we further …
Thymoquinone upregulates TRAIL/TRAILR2 expression and attenuates hepatocellular carcinoma in vivo model.
PMID: Life Sci. 2019 Jul 20:116673. Epub 2019 Jul 20. PMID: 31336121 Abstract Title: Thymoquinone upregulates TRAIL/TRAILR2 expression and attenuates hepatocellular carcinoma in vivo model. Abstract: AIMS: Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related mortality worldwide. Indeed, chemotherapeutic drugs-induced systemic toxicity results in suboptimal cancer treatment. Consequently, there is a need for …
The effect of chronic supplementation of Nigella sativa on splenocytes response in rats following treadmill exercise.
PMID: Drug Chem Toxicol. 2019 May 29:1-6. Epub 2019 May 29. PMID: 31137984 Abstract Title: The effect of chronic supplementation ofon splenocytes response in rats following treadmill exercise. Abstract: ) was shown to recover fatigue and imbalanced immune system. Therefore, effect of chronic administration ofhydroethanolic extract on splenocytes response in sedentary and exercised animals, was …
Thymoquinone attenuates phosphorylation of AKT to inhibit kidney cancer cell proliferation.
PMID: J Food Biochem. 2019 Apr ;43(4):e12793. Epub 2019 Jan 29. PMID: 31353586 Abstract Title: Thymoquinone attenuates phosphorylation of AKT to inhibit kidney cancer cell proliferation. Abstract: Thymoquinone (Tq) is an active compound from Nigella sativa which is used in traditional medicine. The effect of Tq on kidney cancer and the pathway of action remain …
This meta-analysis suggests thatN. sativa seed and seed oil supplementation can significantly reduce serum CRP level.
PMID: Complement Ther Med. 2019 Aug ;45:149-155. Epub 2019 Jun 14. PMID: 31331553 Abstract Title: The effect of Nigella sativa L. supplementation on serum C-reactive protein: A systematic review and meta-analysis of randomized controlled trials. Abstract: OBJECTIVE: Evidence on the efficacy ofNigella sativa supplementation is equivocal, thus the aim of this systematic review and meta-analysis …
Nigella sativa stimulate insulin secretion from isolated rat islets and inhibit the digestion and absorption of (CH2O)n in the gut.
PMID: Biosci Rep. 2019 Aug 2. Epub 2019 Aug 2. PMID: 31375555 Abstract Title: stimulate insulin secretion from isolated rat islets and inhibit the digestion and absorption of (CH2O)n in the gut. Abstract: seeds are traditionally reputed as possessing anti-diabetic properties. As a result, we aim to explore the mechanism of its anti-hyperglycemic activity. This …
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