PMID: Food Chem Toxicol. 2019 Jul 22:110694. Epub 2019 Jul 22. PMID: 31344369 Abstract Title: Long-term exposure to bisphenol A or S promotes glucose intolerance and changes hepatic mitochondrial metabolism in male Wistar rats. Abstract: The present study evaluates the effects of low-level long-term exposure to bisphenol A (BPA) and bisphenol S (BPS) on serum …
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Antioxidants reduce oxidative stress in BPA-exposed spermatozoa.
PMID: Sci Rep. 2019 Jul 22 ;9(1):10584. Epub 2019 Jul 22. PMID: 31332285 Abstract Title: Effect of antioxidants on BPA-induced stress on sperm function in a mouse model. Abstract: In the past few years, bisphenol A, (BPA) an endocrine-disrupting chemical, has received increasing attention because of its detrimental health effects. There is ample evidence to …
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Developmental low-dose exposure to bisphenol A induces chronic inflammation, bone marrow fibrosis and reduces bone stiffness.
PMID: Environ Res. 2019 Jul 11 ;177:108584. Epub 2019 Jul 11. PMID: 31326715 Abstract Title: Developmental low-dose exposure to bisphenol A induces chronic inflammation, bone marrow fibrosis and reduces bone stiffness in female rat offspring only. Abstract: BACKGROUND: Developmental exposure to low doses of the endocrine disruptor bisphenol A (BPA) is known to alter bone …
Non-ionizing radiation created by mobile phone progresses endometrial hyperplasia.
PMID: Arch Med Res. 2019 Feb ;50(2):36-43. Epub 2019 Jun 3. PMID: 31349952 Abstract Title: Non-Ionizing Radiation Created by Mobile Phone Progresses Endometrial Hyperplasia: An Experimental Rat Study. Abstract: BACKGROUND: Non-ionizing radiation is related with many pathologies.AIM: Determine association between non-ionizing radiation and endometrial hyperplasia.METHODS: Fifty oopherectomized Wistar albino rats were administered Estradiol hemihydrate (4 mg/kg) …
Effects of hydrogen-rich water on the nutrient composition and antioxidative characteristics of sprouted black barley.
PMID: Food Chem. 2019 Nov 30 ;299:125095. Epub 2019 Jun 27. PMID: 31279124 Abstract Title: Effects of hydrogen-rich water on the nutrient composition and antioxidative characteristics of sprouted black barley. Abstract: Hydrogen gas (H), a multifunctional signaling molecule, has received increasing attention in recent years. In the present study, hydrogen-rich water (HRW) (2 ppm) was used …
Asiatic acid attenuates pressure overload-induced cardiac fibrosis.
PMID: Int Immunopharmacol. 2019 Jun 26 ;74:105712. Epub 2019 Jun 26. PMID: 31254954 Abstract Title: Asiatic acid inhibits cardiac fibrosis throughNrf2/HO-1 and TGF-β1/Smads signaling pathways in spontaneous hypertension rats. Abstract: OBJECTIVE: Asiatic acid (AA) has been suggested to inhibit pulmonary and hepatic fibrosis, while its influence on cardiac fibrosis remains unclear. We aimed to investigate …
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Protective effects of asiatic acid against pelvic inflammatory disease in rats.
PMID: Exp Ther Med. 2019 Jun ;17(6):4687-4692. Epub 2019 Apr 17. PMID: 31086602 Abstract Title: Protective effects of Asiatic acid against pelvic inflammatory disease in rats. Abstract: Asiatic acid (AA) is one of the major components of the Chinese herband exerts a variety of pharmacological activities. However, the pharmacological effects of AA on pelvic inflammatory …
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Asiatic acid protects dopaminergic neurons from neuroinflammation.
PMID: Biomol Ther (Seoul). 2019 Apr 10. Epub 2019 Apr 10. PMID: 30971058 Abstract Title: Asiatic Acid Protects Dopaminergic Neurons from Neuroinflammation by Suppressing Mitochondrial Ros Production. Abstract: This study sought to evaluate the effects of Asiatic acid in LPS-induced BV2 microglia cells and 1-methyl-4-phenyl-pyridine (MPP)-induced SH-SY5Y cells, to investigate the potential anti-inflammatory mechanisms of …
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Antimicrobial effect of asiatic acid against Clostridium difficile is associated with disruption of membrane permeability.
PMID: Front Microbiol. 2018 ;9:2125. Epub 2018 Sep 7. PMID: 30245677 Abstract Title: Antimicrobial Effect of Asiatic Acid AgainstIs Associated With Disruption of Membrane Permeability. Abstract: Antibiotic resistance is a major concern in, the causative agent of antibiotic-associated diarrhea. Reduced susceptibility to first- and second-line agents is widespread, therefore various attempts have been made to …
Centella asiatica suppresses LPS-induced proinflammatory responses in macrophages.
PMID: Biol Pharm Bull. 2019 ;42(8):1358-1365. PMID: 31366870 Abstract Title: ECa 233 Suppresses LPS-Induced Proinflammatory Responses in Macrophages via Suppressing ERK1/2, p38 MAPK and Akt Pathways. Abstract: A current anti-inflammatory agent often targets the prevention of inflammatory disorder development. The standardized Centella asiatica ECa 233 extract has been previously reported for anti-inflammatory effect. This study …
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