PMID: Nan Fang Yi Ke Da Xue Xue Bao. 2019 Jul 30 ;39(7):778-783. PMID: 31340909 Abstract Title: [Protective effect of procyanidin B2 on intestinal barrier and against enteritis in a mouse model of trinitrobenzene sulphonic acid-induced colitis]. Abstract: OBJECTIVE: To investigate the protective effect of procyanidin B2 (PCB2) on the intestinal barrier and against enteritis …
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Procyanidin B2 inhibits the activation of hepatic stellate cells and angiogenesis via the Hedgehog pathway during liver fibrosis.
PMID: J Cell Mol Med. 2019 Jul 21. Epub 2019 Jul 21. PMID: 31328391 Abstract Title: Procyanidin B2 inhibits the activation of hepatic stellate cells and angiogenesis via the Hedgehog pathway during liver fibrosis. Abstract: BACKGROUND: Liver fibrosis is a wound-healing process of liver featured by the over-deposition of extracellular matrix (ECM) and angiogenesis. However, …
Grape seed procyanidin B2 promotes the autophagy and apoptosis in colorectal cancer cells.
PMID: Onco Targets Ther. 2019 ;12:4109-4118. Epub 2019 May 24. PMID: 31213831 Abstract Title: Grape seed procyanidin B2 promotes the autophagy and apoptosis in colorectal cancer cells via regulating PI3K/Akt signaling pathway. Abstract: Colorectal cancer (CRC) is a major malignancy in China, which is the critical risk of people health. Many natural herbs extracts have …
Identification of the components in a Vaccinium oldhamii extract showing inhibitory activity against influenza virus adsorption.
PMID: Foods. 2019 May 20 ;8(5). Epub 2019 May 20. PMID: 31137514 Abstract Title: Identification of the Components in aExtract Showing Inhibitory Activity against Influenza Virus Adsorption. Abstract: We previously reported that extracts from plants of the Ericaceae genus, commonly known as the kind of blueberry, inhibited the early steps of influenza virus (IFV) infection …
DIM may be a novel preventive and therapeutic approach for the treatment of breast cancers.
PMID: Nutr Cancer. 2019 ;71(6):992-1006. Epub 2019 Apr 29. PMID: 31032639 Abstract Title: 3,3'-Diindolylmethane Inhibits TNF-α- and TGF-β-Induced Epithelial-Mesenchymal Transition in Breast Cancer Cells. Abstract: Epithelial-mesenchymal transition (EMT) is the initial event required by cancer cells. Thus, inhibition of the EMT process could have potential benefits for preventing the spread of cancers. The phytochemicals have …
Carnosic acid attenuates arsenic-induced hepatotoxicity.
PMID: Oxid Med Cell Longev. 2018 ;2018:1421438. Epub 2018 May 2. PMID: 29854073 Abstract Title: Carnosic Acid, a Natural Diterpene, Attenuates Arsenic-Induced Hepatotoxicity via Reducing Oxidative Stress, MAPK Activation, and Apoptotic Cell Death Pathway. Abstract: The present studies have been executed to explore the protective mechanism of carnosic acid (CA) against NaAsO-induced hepatic injury. CA …
Continue reading “Carnosic acid attenuates arsenic-induced hepatotoxicity.”
Carnosic acid attenuates acrylamide-induced retinal toxicity in zebrafish embryos.
PMID: Exp Eye Res. 2018 10 ;175:103-114. Epub 2018 Jun 18. PMID: 29928899 Abstract Title: Carnosic acid attenuates acrylamide-induced retinal toxicity in zebrafish embryos. Abstract: Acrylamide (ACR) is a water-soluble chemical used widely in industry, which can be formed in tobacco smoke and in starchy foods cooked at high temperatures. ACR is considered to be …
Carnosic acid improves outcome after repetitive mild traumatic brain injury.
PMID: J Neurotrauma. 2019 Jul 1 ;36(13):2147-2152. Epub 2019 Mar 26. PMID: 30672378 Abstract Title: Carnosic Acid Improves Outcome after Repetitive Mild Traumatic Brain Injury. Abstract: In the majority of cases, the cognitive and behavioral impairments resulting from a mild traumatic brain injury (TBI) (also referred to as concussion) wane within days to weeks. In …
Continue reading “Carnosic acid improves outcome after repetitive mild traumatic brain injury.”
Interaction mechanism of carnosic acid against glycosidase (α-amylase and α-glucosidase).
PMID: Int J Biol Macromol. 2019 Jul 26. Epub 2019 Jul 26. PMID: 31356939 Abstract Title: Interaction mechanism of carnosic acid against glycosidase (α-amylase and α-glucosidase). Abstract: Inhibition the activity of glycosidase is an effective method for the treatment and prevention of diabetes. In this study, enzymatic kinetics, fluorescence spectrum experiment, starch granule digestion, molecular …
Sesquiterpene rich essential oil from Nepalese Bael tree as potential antiproliferative agent.
PMID: Fitoterapia. 2019 Jul 11:104266. Epub 2019 Jul 11. PMID: 31302251 Abstract Title: Sesquiterpene rich essential oil from Nepalese Bael tree (Aegle marmelos (L.) Correa) as potential antiproliferative agent. Abstract: Aegle marmelos (L.) Corr. (Rutaceae), also known as Bael tree, is an herbal traditional remedy in the South East Asia. In the present work, the …
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