PMID: Molecules. 2019 May 7 ;24(9). Epub 2019 May 7. PMID: 31067626 Abstract Title: Betulinic Acid Prevents the Acquisition of Ciprofloxacin-Mediated Mutagenesis in. Abstract: The occurrence of damage on bacterial DNA (mediated by antibiotics, for example) is intimately associated with the activation of the SOS system. This pathway is related to the development of mutations …
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Rats born to mothers exposed to Wi-Fi and cell phone electromagnetic fields exhibit elevated oxidative stress in kidneys and testes and may cause precocious puberty.
PMID: Biol Trace Elem Res. 2013 Dec ;156(1-3):221-9. Epub 2013 Oct 8. PMID: 24101576 Abstract Title: Wi-Fi (2.45 GHz)- and mobile phone (900 and 1800 MHz)-induced risks on oxidative stress and elements in kidney and testis of rats during pregnancy and the development of offspring. Abstract: The present study was designed to determine the effects …
Betulinic acid suppresses Th17 response and ameliorates psoriasis-like murine skin inflammation.
PMID: Int Immunopharmacol. 2019 Aug ;73:343-352. Epub 2019 May 23. PMID: 31129421 Abstract Title: Betulinic acid suppresses Th17 response and ameliorates psoriasis-like murine skin inflammation. Abstract: Psoriasis is a common inflammatory skin disease. Current treatment for psoriasis relies on conventional immunosuppressive agents. However, long-term treatment with global immunosuppression may cause various side effects. Thus, it …
Betulinic acid lowers lipid accumulation in adipocytes through enhanced NCoA1-PPARγ interaction.
PMID: J Infect Public Health. 2019 May 24. Epub 2019 May 24. PMID: 31133421 Abstract Title: Betulinic acid lowers lipid accumulation in adipocytes through enhanced NCoA1-PPARγ interaction. Abstract: BACKGROUND: Investigation for a naturally occurring anti-obesity drug has become the need of society all over the world. Betulinic acid (BA) is a lupane-type pentacyclic triterpene and …
Exposure to 2400 MHz induces oxidative stress in the brains and ovaries of female rats. Exposure, especially in the prenatal period, results in delayed puberty and postnatal growth restriction.
PMID: Electromagn Biol Med. 2015 Mar ;34(1):63-71. Epub 2014 Jan 24. PMID: 24460416 Abstract Title: The effects of long-term exposure to a 2450 MHz electromagnetic field on growth and pubertal development in female Wistar rats. Abstract: The aim of this study was to investigate the effects of a 2450 MHz electromagnetic field (EMF) (wireless internet frequency) on …
Betulinic acid derivative BA5 had a potent anti-inflammatory activity on a model of parasite-driven heart disease.
PMID: Front Immunol. 2019 ;10:1257. Epub 2019 Jun 11. PMID: 31244833 Abstract Title: Betulinic Acid Derivative BA5, Attenuates Inflammation and Fibrosis in Experimental Chronic Chagas Disease Cardiomyopathy by Inducing IL-10 and M2 Polarization. Abstract: Chronic Chagas disease cardiomyopathy (CCC) is a major cause of heart disease in Latin America and treatment for this condition is …
Olive leaf extract reduces oxidative stress and oxidative stress-related glucose metabolism disruption induced by 2.45 GHz Wi-Fi signals.
PMID: Environ Toxicol Pharmacol. 2013 Nov ;36(3):826-34. Epub 2013 Aug 3. PMID: 23994945 Abstract Title: Effects of olive leave extract on metabolic disorders and oxidative stress induced by 2.45 GHz WIFI signals. Abstract: We investigated the effect of olive leaves extract administration on glucose metabolism and oxidative response in liver and kidneys of rats exposed …
Betulinic acid suppresses ovarian cancer cell proliferation through induction of apoptosis.
PMID: Biomolecules. 2019 Jul 3 ;9(7). Epub 2019 Jul 3. PMID: 31277238 Abstract Title: Betulinic Acid Suppresses Ovarian Cancer Cell Proliferation through Induction of Apoptosis. Abstract: Ovarian cancer is one of the leading causes of cancer deaths worldwide in women, and the most malignant cancer among the different gynecological cancers. In this study, we explored …
This study demonstrates the adverse effects of electromagnetic radiation on testicular parenchyma in rats.
PMID: J Toxicol Environ Health A. 2014 ;77(13):747-50. PMID: 24839928 Abstract Title: Structural and ultrastructural study of rat testes influenced by electromagnetic radiation. Abstract: This study was conducted to investigate the influence of whole-body electromagnetic radiation (EMR) on testicular parenchyma of Wistar rats. Sexually mature rats were subjected to pulsed electromagnetic field at frequency of …
2.4 GHz electromagnetic field exposure increases DNA oxidation in brain and plasma and plasma protein oxidation in rats. Garlic reduces biomarkers of both DNA and protein oxidation, suggesting it protects against the adverse effects of EMF radiation.
PMID: Int J Radiat Biol. 2014 Oct ;90(10):892-6. Epub 2014 Jun 25. PMID: 24844368 Abstract Title: Increased DNA oxidation (8-OHdG) and protein oxidation (AOPP) by low level electromagnetic field (2.45 GHz) in rat brain and protective effect of garlic. Abstract: PURPOSE: To investigate the oxidative damage and protective effect of garlic on rats exposed to …
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