PMID: Pain. 2019 Jan ;160(1):117-135. PMID: 30169422 Abstract Title: Betulinic acid, derived from the desert lavender Hyptis emoryi, attenuates paclitaxel-, HIV-, and nerve injury-associated peripheral sensory neuropathy via block of N- and T-type calcium channels. Abstract: The Federal Pain Research Strategy recommended development of nonopioid analgesics as a top priority in its strategic plan to …
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1800 MHz radiofrequency fields stimulates pro-inflammatory responses in microglia and astrocytes in vitro.
PMID: PLoS One. 2014 ;9(9):e108318. Epub 2014 Oct 2. PMID: 25275372 Abstract Title: Differential pro-inflammatory responses of astrocytes and microglia involve STAT3 activation in response to 1800 MHz radiofrequency fields. Abstract: Microglia and astrocytes play important role in maintaining the homeostasis of central nervous system (CNS). Several CNS impacts have been postulated to be associated …
Ursolic acid treatment may be a potential therapeutic strategy to improve muscle-specific pathological consequences of spinal cord injury.
PMID: PLoS One. 2018 ;13(8):e0203042. Epub 2018 Aug 29. PMID: 30157245 Abstract Title: Effects of ursolic acid on sub-lesional muscle pathology in a contusion model of spinal cord injury. Abstract: Spinal Cord Injury (SCI) results in severe sub-lesional muscle atrophy and fiber type transformation from slow oxidative to fast glycolytic, both contributing to functional deficits …
Ursolic acid might be a potential therapeutic of retinoic acid-induced acute osteoporosis.
PMID: Chin J Integr Med. 2019 Mar ;25(3):210-215. Epub 2018 Aug 30. PMID: 30159645 Abstract Title: Ursolic Acid Prevents Retinoic Acid-Induced Bone Loss in Rats. Abstract: OBJECTIVE: To examine the effects of ursolic acid (UA) on mitigating retinoic acid (RA)-induced osteoporosis in rats.METHODS: Fifty female Sprague-Dawley rats were randomly divided into the control group (n=10) …
Long-term 1.8 GHZ RF-EMF induces memory impairments in rats that persist 2 weeks after radiation.
PMID: Electromagn Biol Med. 2013 Mar ;32(1):95-120. Epub 2013 Jan 15. PMID: 23320614 Abstract Title: Transient and cumulative memory impairments induced by GSM 1.8 GHz cell phone signal in a mouse model. Abstract: This study was designed to investigate the transient and cumulative impairments in spatial and non-spatial memory of C57Bl/6J mice exposed to GSM 1.8 GHz …
The present findings indicated that ursolic acid may be a possible therapeutic agent against diabetic nephropathy.
PMID: Mol Med Rep. 2018 Nov ;18(5):4675-4681. Epub 2018 Sep 3. PMID: 30221655 Abstract Title: Ursolic acid alleviates inflammation and against diabetes‑induced nephropathy through TLR4‑mediated inflammatory pathway. Abstract: Ursolic acid (UA) is a triterpenoid isolated from Chinese herbal medicine. It is extensively distributed in the plant kingdom in at least 63 Chinese herbal medicines of 26 families. …
Higher duration of exposure to 900 MHz RF-EMF leads to increased DNA damage in quail embryos.
PMID: Int J Radiat Biol. 2013 Sep ;89(9):756-63. Epub 2013 May 13. PMID: 23578013 Abstract Title: GSM 900 MHz cellular phone radiation can either stimulate or depress early embryogenesis in Japanese quails depending on the duration of exposure. Abstract: PURPOSE: Our study was designed to assess the effects of low intensity radiation of a GSM …
Ursolic acid a promising candidate in the therapeutics of breast cancer.
PMID: Biomed Pharmacother. 2018 Dec ;108:752-756. Epub 2018 Sep 21. PMID: 30248543 Abstract Title: Ursolic acid a promising candidate in the therapeutics of breast cancer: Current status and future implications. Abstract: Breast cancer [BC] is the deadliest neoplasm in women globally and the second leading cause of cancer associated deaths. Current treatment methods include chemotherapy, …
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Ursolic acid may ameliorate the deleterious effects of diet-induced obesity and associated complications such as hepatic fibrosis.
PMID: Nutrients. 2018 Nov 9 ;10(11). Epub 2018 Nov 9. PMID: 30423963 Abstract Title: Ursolic Acid Attenuates Hepatic Steatosis, Fibrosis, and Insulin Resistance by Modulating the Circadian Rhythm Pathway in Diet-Induced Obese Mice. Abstract: The aim of the current study was to elucidate the effects of long-term supplementation with dietary ursolic acid (UR) on obesity …
1800 MHz RF-EMF fields result in cell type-dependent DNA damage and a significant increase in reactive oxygen species level, however researchers conclude it doesn’t contribute to cell dysfunction.
PMID: PLoS One. 2013 ;8(1):e54906. Epub 2013 Jan 23. PMID: 23355902 Abstract Title: Cell type-dependent induction of DNA damage by 1800 MHz radiofrequency electromagnetic fields does not result in significant cellular dysfunctions. Abstract: BACKGROUND: Although IARC clarifies radiofrequency electromagnetic fields (RF-EMF) as possible human carcinogen, the debate on its health impact continues due to the …
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