PMID: Spectrochim Acta A Mol Biomol Spectrosc. 2018 Oct 5 ;203:222-228. Epub 2018 May 26. PMID: 29870906 Abstract Title: Non-enzymatic conversion of primary oxidation products of Docosahexaenoic acid into less toxic acid molecules. Abstract: Docosahexaenoic acid (DHA) is long chain omega-3 fatty acid with known health benefits and clinical significance. However, 4-hydroxy hexenal (HHE), an …
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Bioactivity-guided screening identifies pheophytin a as a potent anti-hepatitis C virus compound from Lonicera hypoglauca Miq.
PMID: Biochem Biophys Res Commun. 2009 Jul 24 ;385(2):230-5. Epub 2009 May 19. PMID: 19450556 Abstract Title: Bioactivity-guided screening identifies pheophytin a as a potent anti-hepatitis C virus compound from Lonicera hypoglauca Miq. Abstract: Chronic hepatitis C virus (HCV) infection is a worldwide public issue. In this study, we performed bioactivity-guided screening of the Lonicera …
Protective effects of Flos lonicera extract on acute liver injury by dimethylnitrosamine.
PMID: J Nat Med. 2010 Jul ;64(3):288-94. Epub 2010 Mar 20. PMID: 20306146 Abstract Title: Protective effects of Flos lonicera extract on acute liver injury by dimethylnitrosamine-induced in rats. Abstract: The aim of this study is to investigate effects of Flos lonicera extract (FLE) on acute liver injury model rats which induced by 35 mg/kg …
Oxidation products of alpha-linolenic acid (ALA), oxylipins, enhance the longevity-promoting properties of ALA in C. elegans.
PMID: Aging Cell. 2017 10 ;16(5):1125-1135. Epub 2017 Aug 3. PMID: 28772063 Abstract Title: Theω-3 fatty acid α-linolenic acid extends Caenorhabditis elegans lifespan via NHR-49/PPARα and oxidation to oxylipins. Abstract: The dietary intake ofω-3 polyunsaturated fatty acids has been linked to a reduction in the incidence of aging-associated disease including cardiovascular disease and stroke. Additionally, …
Polyphenolic fraction of Lonicera caerulea L. fruits reduces oxidative stress and inflammatory markers induced by lipopolysaccharide in gingival fibroblasts.
PMID: Food Chem Toxicol. 2010 Jun ;48(6):1555-61. Epub 2010 Mar 21. PMID: 20332009 Abstract Title: Polyphenolic fraction of Lonicera caerulea L. fruits reduces oxidative stress and inflammatory markers induced by lipopolysaccharide in gingival fibroblasts. Abstract: The most common oral diseases have a microbial aetiology. Pathogenic bacteria liberate a number of irritating agents including a lipopolysaccharide …
This review describes the anti-inflammatory and antioxidant effects of oxidized omega-3 fatty acids.
PMID: Biochimie. 2016 Jan ;120:56-61. Epub 2015 Jun 23. PMID: 26112019 Abstract Title: Non-enzymatic cyclic oxygenated metabolites of omega-3 polyunsaturated fatty acid: Bioactive drugs? Abstract: Non-enzymatic oxygenated metabolites derived from polyunsaturated fatty acids (PUFA) are formed in vivo through free radical reaction under oxidative stress conditions. It has been over twenty-five years since the discovery of …
Metabonomics study of the protective effects of Lonicera japonica extract on acute liver injury.
PMID: J Pharm Biomed Anal. 2010 Sep 21 ;53(1):98-102. Epub 2010 Mar 17. PMID: 20371156 Abstract Title: Metabonomics study of the protective effects of Lonicera japonica extract on acute liver injury in dimethylnitrosamine treated rats. Abstract: A metabonomics approach, consisting of gas chromatography coupled to mass spectrometry (GC/MS) and a multivariate statistical technique, was developed …
This review indicates that omega-3s and their oxygenated metabolites may play a role in preventing atherothrombosis.
PMID: Biochim Biophys Acta. 2015 Apr ;1851(4):485-95. Epub 2014 Sep 28. PMID: 25263947 Abstract Title: Omega-3 polyunsaturated fatty acids and oxygenated metabolism in atherothrombosis. Abstract: Numerous epidemiological studies and clinical trials have reported the health benefits of omega-3 polyunsaturated fatty acids (PUFA), including a lower risk of coronary heart diseases. This review mainly focuses on …
Luteolin ameliorates experimental lung fibrosis both in vivo and in vitro.
PMID: J Agric Food Chem. 2010 Nov 24 ;58(22):11653-61. Epub 2010 Oct 19. PMID: 20958047 Abstract Title: Luteolin ameliorates experimental lung fibrosis both in vivo and in vitro: implications for therapy of lung fibrosis. Abstract: Lonicera japonica (Caprifoliaceae) has been known as an anti-inflammatory herb in traditional Chinese medicine for thousands of years and is …
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These results demonstrate that Lonicera japonica possesses potent neuroprotective activity.
PMID: Food Chem Toxicol. 2011 Apr ;49(4):1011-9. Epub 2011 Jan 12. PMID: 21237235 Abstract Title: The neuroprotective effects of Lonicera japonica THUNB. against hydrogen peroxide-induced apoptosis via phosphorylation of MAPKs and PI3K/Akt in SH-SY5Y cells. Abstract: We investigated the neuroprotective effects of Lonicera japonica THUNB. (Caprifoliaceae) (LJ) extract against hydrogen peroxide (H(2)O(2)), a toxin created …
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