Category Archives: Uncategorized

PMID:  Int Immunopharmacol. 2019 Jul 17 ;75:105742. Epub 2019 Jul 17. PMID: 31325727 Abstract Title:  Activation of Nrf2/HO-1 signal with Myricetin for attenuating ECM degradation in human chondrocytes and ameliorating the murine osteoarthritis. Abstract:  BACKGROUND: Osteoarthritis (OA), one of the prevailing joint degenerative disorders, contributes to the disability around the world. However, no effective therapeutic …

Continue reading “Myricetin possesses the therapeutic potential on osteoarthritis.”

PMID:  Ecotoxicol Environ Saf. 2019 Jul 17 ;182:109447. Epub 2019 Jul 17. PMID: 31325809 Abstract Title:  Selenium decreases methylmercury and increases nutritional elements in rice growing in mercury-contaminated farmland. Abstract:  Methylmercury (MeHg) in rice grains grown in Hg-contaminated areas has raised environmental health concerns. Pot experiments found that selenium (Se) could reduce MeHg levels in …

Continue reading “Selenium decreases methylmercury and increases nutritional elements in rice growing in mercury-contaminated farmland.”

PMID:  Dose Response. 2019 Apr-Jun;17(2):1559325819855538. Epub 2019 Jun 11. PMID: 31217757 Abstract Title:  Sulforaphane Attenuates Endometriosis in Rat Models Through Inhibiting PI3K/Akt Signaling Pathway. Abstract:  Sulforaphane exerts anti-inflammatory activity in inflammatory diseases. The endometriosis (EM) is accompanied by chronic inflammation. The present study aims to explore the therapeutic effects of sulforaphane on EM and its …

Continue reading “Sulforaphane exhibits antiproliferative, apoptotic, anti-inflammatory, and anti-angiogenic properties and ameliorates a rat model of endometriosis.”

PMID:  J Agric Food Chem. 2019 Jul 17 ;67(28):7844-7854. Epub 2019 Jul 9. PMID: 31241937 Abstract Title:  Sulforaphane Inhibits Nonmuscle Invasive Bladder Cancer Cells Proliferation through Suppression of HIF-1α-Mediated Glycolysis in Hypoxia. Abstract:  Bladder cancer is the fourth common cancer among men and more than 70% of the bladder cancer is nonmuscle invasive bladder cancer …

Continue reading “Sulforaphane inhibited proliferation of bladder cancer cells by 29.7 ± 4.6% under normal oxygen conditions and 48.3 ± 5.2% under hypoxic conditions through suppression of HIF-1α-mediated glycolysis.”

Google has recently (June 2019) used their power to manipulate public opinion in favor of the Pro Vaccine Argument!

PMID:  Eur J Pharmacol. 2019 Jun 29 ;859:172513. Epub 2019 Jun 29. PMID: 31260654 Abstract Title:  Combinations of the antioxidants sulforaphane or curcumin and the conventional antineoplastics cisplatin or doxorubicin as prospects for anticancer chemotherapy. Abstract:  Drugs used in clinical oncology have narrow therapeutic indices with adverse toxicity often involving oxidative damage. Chemoresistance to these …

Continue reading “This review describes the role of antioxidants like sulforaphane and curcumin in combatting chemoresistance and chemotherapy-induced oxidative stress through NF-kappaB and HIF-1a inhibition.”

PMID:  Am J Clin Nutr. 2019 Jul 3. Epub 2019 Jul 3. PMID: 31268126 Abstract Title:  Dose-dependent detoxication of the airborne pollutant benzene in a randomized trial of broccoli sprout beverage in Qidong, China. Abstract:  BACKGROUND: Airborne pollutants have collectively been classified as a known human carcinogen and, more broadly, affect the health of hundreds …

Continue reading “Sulforaphane detoxifies benzene, an air pollutant, in a dose-dependent manner and may attentuate attenuate associated long-term health risks of air pollution.”

PMID:  Biochem J. 2002 Jul 15 ;365(Pt 2):489-96. PMID: 11939906 Abstract Title:  Differential metabolism of dihomo-gamma-linolenic acid and arachidonic acid by cyclo-oxygenase-1 and cyclo-oxygenase-2: implications for cellular synthesis of prostaglandin E1 and prostaglandin E2. Abstract:  Prostaglandin (PG) E(1) has been shown to possess anti-inflammatory properties and to modulate vascular reactivity. These activities are sometimes distinct …

Continue reading “Dietary interventions to increase the dihomo-gamma-linoleic acid to arachidonic acid ratio may not necessarily decrease PGE2 synthesis in tissues where COX-1 enzymes predominate over COX-2.”

PMID:  Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2019 Jun 28 ;44(6):701-705. PMID: 31304933 Abstract Title:  [Role of sulforaphane in improving negative symptoms and cognitive symptoms of schizophrenia and the underlying mechanism]. Abstract:  The negative symptoms and cognitive symptoms of schizophrenia patients are still clinical problems to be solved. Schizophrenia patients are abnormal …

Continue reading “Sulforaphane’s antioxidant, anti-inflammatory, and histone deacetylase inhibiting properties may improve schizophrenia symptoms.”

PMID:  Biochim Biophys Acta Mol Basis Dis. 2019 Jul 8 ;1865(10):2586-2594. Epub 2019 Jul 8. PMID: 31295528 Abstract Title:  Sulforaphane protects against ethanol-induced apoptosis in neural crest cells through restoring epithelial-mesenchymal transition by epigenetically modulating the expression of Snail1. Abstract:  Ethanol-induced apoptosis in neural crest cells (NCCs), a multipotent progenitor cell population, is implicated in …

Continue reading “Sulforaphane protects against ethanol-induced apoptosis in neural crest cells, a characteristic of Fetal Alcohol Syndrome, through restoration of Snail1 expression and epithelial-mesenchymal transition.”