PMID: Front Microbiol. 2019 ;10:990. Epub 2019 May 8. PMID: 31134028 Abstract Title: Antibiofilm and Antivirulence Efficacies of Flavonoids and Curcumin Against. Abstract: is well adapted to hospital environments, and the persistence of its chronic infections is mainly due to its ability to form biofilms resistant to conventional antibiotics and host immune systems. Hence, the …
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Phloretin suppresses metastasis by targeting protease and inhibits cancer stemness and angiogenesis in human cervical cancer cells.
PMID: Phytomedicine. 2019 May 18 ;62:152964. Epub 2019 May 18. PMID: 31153059 Abstract Title: Phloretin suppresses metastasis by targeting protease and inhibits cancer stemness and angiogenesis in human cervical cancer cells. Abstract: BACKGROUND: Phloretin, a dihydrochalcone flavonoid, possesses anti-inflammatory activity and inhibits the growth of various cancers. However, the flavonoid's effect on cervical cancer metastasis …
Phloretin attenuates behavior deficits and neuroinflammatory response in MPTP induced Parkinson’s disease in mice.
PMID: Life Sci. 2019 Jun 25:116600. Epub 2019 Jun 25. PMID: 31251998 Abstract Title: Phloretin attenuates behavior deficits and neuroinflammatory response in MPTP induced Parkinson's disease in mice. Abstract: Neuroinflammation is one of the significant neuropathological conditions in Parkinson's disease (PD) which is due to microglial and astrocytes activation leads to progressive dopaminergic neuronal loss. …
Phloretin and phloridzin improve insulin sensitivity and enhance glucose uptake.
PMID: Exp Cell Res. 2019 Jul 4:111480. Epub 2019 Jul 4. PMID: 31279631 Abstract Title: Phloretin and phloridzin improve insulin sensitivity and enhance glucose uptake by subverting PPARγ/Cdk5 interaction in differentiated adipocytes. Abstract: Activators of peroxisome proliferator-activated receptor-γ (PPARγ agonists) are therapeutically promising candidates against insulin resistance and hyperglycemia. Synthetic PPARγ agonists are known to …
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Role of apple phytochemicals, phloretin and phloridzin, in modulating processes related to intestinal inflammation.
PMID: Nutrients. 2019 May 25 ;11(5). Epub 2019 May 25. PMID: 31130634 Abstract Title: Role of Apple Phytochemicals, Phloretin and Phloridzin, in Modulating Processes Related to Intestinal Inflammation. Abstract: Plant-derived food consumption has gained attention as potential intervention for the improvement of intestinal inflammatory diseases. Apple consumption has been shown to be effective at ameliorating …
Chemopreventive potential of apple pulp callus against colorectal cancer cell proliferation and tumorigenesis.
PMID: J Med Food. 2019 Jun ;22(6):614-622. Epub 2019 May 6. PMID: 31058564 Abstract Title: Chemopreventive Potential of Apple Pulp Callus Against Colorectal Cancer Cell Proliferation and Tumorigenesis. Abstract: This study focused on the evaluation of the chemopreventive potential of tissueculture of the"Mela Rosa Marchigiana"apple (MRM callus) that allows the amplification of secondary metabolites. The …
Antiviral activity of aged green tea extract in model food systems and under gastric conditions.
PMID: Int J Food Microbiol. 2019 Mar 2 ;292:101-106. Epub 2018 Dec 21. PMID: 30594741 Abstract Title: Antiviral activity of aged green tea extract in model food systems and under gastric conditions. Abstract: Aged-green tea extract (GTE) is known to reduce the infectivity of hepatitis A virus (HAV) and murine norovirus (MNV), a human norovirus …
Alkali-soluble pectin suppresses IgE production in human myeloma cell line in vitro.
PMID: Cytotechnology. 2019 Apr ;71(2):573-581. Epub 2019 Feb 15. PMID: 30771057 Abstract Title: Alkali-soluble pectin suppresses IgE production in human myeloma cell line in vitro. Abstract: We found that strawberry (Fragaria x ananassa) extract has an IgE production suppressive activity and its oral administration improved skin manifestation in atopic dermatitis model mice. In present study, …
Apple phenolic extracts strongly inhibit α-glucosidase activity.
PMID: Plant Foods Hum Nutr. 2019 Jul 13. Epub 2019 Jul 13. PMID: 31302831 Abstract Title: Apple Phenolic Extracts Strongly Inhibitα-Glucosidase Activity. Abstract: The beneficial health effects of apple consumption are well known, however, little is known about the potential of its phenolic fractions to inhibitα-glucosidases and thereafter to treat diseases related to the carbohydrate …
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Modified apple polysaccharide regulates microbial dysbiosis to suppress high-fat diet-induced obesity.
PMID: Eur J Nutr. 2019 Jul 16. Epub 2019 Jul 16. PMID: 31312904 Abstract Title: Modified apple polysaccharide regulates microbial dysbiosis to suppress high-fat diet-induced obesity in C57BL/6J mice. Abstract: PURPOSE: Obesity, substantially increasing the risk of diseases such as metabolic diseases, becomes a major health challenge. In this study, we, therefore, investigated the effect …
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