PMID: J Exp Clin Cancer Res. 2020 May 14 ;39(1):88. Epub 2020 May 14. PMID: 32410646 Abstract Title: Promotion of ubiquitination-dependent survivin destruction contributes to xanthohumol-mediated tumor suppression and overcomes radioresistance in human oral squamous cell carcinoma. Abstract: BACKGROUND: Overexpression of survivin plays a crucial role in tumorigenesis and correlates with poor prognosis in human …
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Xanthohumol suppresses glioblastoma via modulation of Hexokinase 2 -mediated glycolysis
PMID: J Cancer. 2020 ;11(14):4047-4058. Epub 2020 Apr 6. PMID: 32368287 Abstract Title: Xanthohumol suppresses glioblastoma via modulation of Hexokinase 2 -mediated glycolysis. Abstract: Deregulation of aerobic glycolysis is a common phenomenon in human cancers, including glioblastoma (GBM). In the present study, we demonstrated that the natural compound xanthohumol has a profound anti-tumor effect on …
Xanthohumol regulates miR-4749-5p-inhibited RFC2 signalling in enhancing temozolomide cytotoxicity to glioblastoma.
PMID: Life Sci. 2020 May 15:117807. Epub 2020 May 15. PMID: 32422304 Abstract Title: Xanthohumol regulates miR-4749-5p-inhibited RFC2 signaling in enhancing temozolomide cytotoxicity to glioblastoma. Abstract: AIMS: Xanthohumol (XN), a natural prenylated flavonoid isolated from Humulus lupulus L. (hops), possess the therapeutic effects in glioblastoma multiforme (GBM), which is a grade IV aggressive glioma in …
Therapeutic effect of seaweed derived xanthophyl carotenoid on obesity management; overview of the last decade.
PMID: Int J Mol Sci. 2020 Apr 3 ;21(7). Epub 2020 Apr 3. PMID: 32260306 Abstract Title: Therapeutic Effect of Seaweed Derived Xanthophyl Carotenoid on Obesity Management; Overview of the Last Decade. Abstract: Present-day lifestyles associated with high calorie-fat intake and accumulation, as well as energy imbalance, have led to the development of obesity and …
Fucoxanthin treatment inhibits nasopharyngeal carcinoma cell proliferation.
PMID: Environ Toxicol. 2020 May 25. Epub 2020 May 25. PMID: 32449842 Abstract Title: Fucoxanthin treatment inhibits nasopharyngeal carcinoma cell proliferation through induction of autophagy mechanism. Abstract: Nasopharyngeal carcinoma (NPC) arises from the epithelium of the nasopharyngeal mucosa. Elderly people above the age of 65 years are more susceptible to NPC. Nasopharyngectomy is the renowned treatment …
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The fucoidan has reduced LPS induced cytotoxicity in IC-21 macrophage at a dose depended on manner.
PMID: Int J Biol Macromol. 2020 May 21. Epub 2020 May 21. PMID: 32446898 Abstract Title: Studies on isolation, characterization of fucoidan from brown algae Turbinaria decurrens and evaluation of it's in vivo and in vitro anti-inflammatory activities. Abstract: In the present study, the anti-nociception and anti-inflammatory activity of fucoidan isolated from T. Decurrens on …
Immunomodulating properties of carrageenan From Tichocarpus Crinitus.
PMID: Inflammation. 2020 Mar 24. Epub 2020 Mar 24. PMID: 32212036 Abstract Title: Immunomodulating Properties of Carrageenan from Tichocarpus crinitus. Abstract: Several in vivo immunotropic effects ofκ/β-carrageenan isolated from the red algae Tichocarpus crinitus were studied, by orally administering it at 100 mg/kg/day to mice for 7 days. Serum levels of IFN-γ, IL-12, IL-1β, and IL-4 were …
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The comparative analysis of antiviral activity of native and modified fucoidans from brown algae Fucus evanescens.
PMID: Mar Drugs. 2020 Apr 22 ;18(4). Epub 2020 Apr 22. PMID: 32331442 Abstract Title: The Comparative Analysis of Antiviral Activity of Native and Modified Fucoidans from Brown AlgaeIn Vitro and In Vivo. Abstract: The enzymatic depolymerization of fucoidans from brown algae allowed the production of their standardized derivatives with different biological activities. This work …
Rhamnan sulphate is a potential candidate for the treatment of influenza virus infections.
PMID: Mar Drugs. 2020 May 13 ;18(5). Epub 2020 May 13. PMID: 32414158 Abstract Title: Anti-Influenza A Virus Activity of Rhamnan Sulfate from Green Algaein Mice with Normal and Compromised Immunity. Abstract: Influenza viruses cause a significant public health burden each year despite the availability of anti-influenza drugs and vaccines. Therefore, new anti-influenza virus agents …
Microalgae extracts: potential anti-Trypanosoma cruzi agents?
PMID: Biomed Pharmacother. 2020 May 1 ;127:110178. Epub 2020 May 1. PMID: 32371317 Abstract Title: Microalgae extracts: Potential anti-Trypanosoma cruzi agents? Abstract: INTRODUCTION: Chagas disease, caused by the protozoan parasiteTrypanosoma cruzi, has no effective treatment available. On the other hand, microalgae are aquatic organisms that constitute an interesting reservoir of biologically active metabolites. Moreover, some …
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