PMID: Zhonghua Xue Ye Xue Za Zhi. 2019 Mar 14 ;40(3):204-208. PMID: 30929387 Abstract Title: [Effects of artesunate combined with bortezomib on apoptosis and autophagy of acute myeloid leukemia cellsand its mechanism]. Abstract: To investigate the effects of artesunate combined with bortezomib on the proliferation, apoptosis and autophagy of human acute myeloid leukemia cell lines …
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Artesunate enhances the cytotoxicity of 5-aminolevulinic acid-based sonodynamic therapy against mouse mammary tumor cells.
PMID: Molecules. 2017 Mar 27 ;22(4). Epub 2017 Mar 27. PMID: 28346389 Abstract Title: Artesunate Enhances the Cytotoxicity of 5-Aminolevulinic Acid-Based Sonodynamic Therapy against Mouse Mammary Tumor Cells In Vitro. Abstract: Sonodynamic therapy (SDT) kills tumor cells through the synergistic effects of ultrasound (US) and a sonosensitizer agent. 5-Aminolevulinic acid (5-ALA) has been used as …
Effects of artesunate against Trypanosma cruzi.
PMID: Exp Parasitol. 2015 Sep ;156:26-31. Epub 2015 May 27. PMID: 26024969 Abstract Title: Effects of artesunate against Trypanosma cruzi. Abstract: Therapy against Trypanosma cruzi relies on only two chemically related nitro-derivative drugs, benznidazole and nifurtimox, both limited by poor efficacy and toxicity. It is suspected that with prolonged usage of these drugs, resistant parasites …
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Artesunate can inhibit the growth of gastric adenocarcinoma cells SGC-7901 and induce the cell apoptosis.
PMID: Arch Med Res. 2017 10 ;48(7):623-630. Epub 2018 Mar 12. PMID: 29544887 Abstract Title: Inhibitory Effect of Artesunate on Growth and Apoptosis of Gastric Cancer Cells. Abstract: OBJECTIVE: The present study aimed to explore the inhibitory effect of artesunate on the growth and apoptosis of gastric cancer cells, in order to search for high …
Artesunate activates the intrinsic apoptosis of HCT116 cells.
PMID: Molecules. 2017 Aug 8 ;22(8). Epub 2017 Aug 8. PMID: 28786914 Abstract Title: Artesunate Activates the Intrinsic Apoptosis of HCT116 Cells through the Suppression of Fatty Acid Synthesis and the NF-κB Pathway. Abstract: The artemisinin compounds, which are well-known for their potent therapeutic antimalarial activity, possess in vivo and in vitro antitumor effects. Although …
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Artesunate attenuate chronic graft-versus-host disease by regulating Th17/Treg balance
PMID: Zhonghua Xue Ye Xue Za Zhi. 2019 Jan 14 ;40(1):63-68. PMID: 30704231 Abstract Title: [Artesunate attenuate chronic graft-versus-host disease by regulating Th17/Treg balance]. Abstract: To investigate the effects of artesunate treatment on chronic graft-versus-host disease (cGVHD).Recipient BALB/c mice received 8× 10(6) bone marrow cells with 8×10(6) spleen cells from B10D2 mice. Artesunate solubilized in …
Artesunate alleviates liver fibrosis by regulating ferroptosis signaling pathway.
PMID: Biomed Pharmacother. 2019 Jan ;109:2043-2053. Epub 2018 Nov 26. PMID: 30551460 Abstract Title: Artesunate alleviates liver fibrosis by regulating ferroptosis signaling pathway. Abstract: Liver fibrosis is a progression of chronic liver disease, which lacks effective therapies in the world. Attractively, more and more evidences show that natural products are safe and effective in the …
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This review provides an overview of primary pharmacological mechanism of artesunate and its potential therapeutic effects on neurological disorders.
PMID: Biomed Res Int. 2016 ;2016:1489050. Epub 2016 Dec 27. PMID: 28116289 Abstract Title: The Potential Therapeutic Effects of Artesunate on Stroke and Other Central Nervous System Diseases. Abstract: Artesunate is an important agent for cerebral malaria and all kinds of other severe malaria because it is highly efficient, lowly toxic, and well-tolerated. Loads of …
Effects of microwave heating on the migration of substances from melamine formaldehyde tableware.
PMID: Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2014 ;31(9):1616-24. Epub 2014 Aug 18. PMID: 25068920 Abstract Title: Effects of microwave heating on the migration of substances from melamine formaldehyde tableware. Abstract: Melamine formaldehyde (MF) tableware, after undergoing repeated heating in a microwave oven for 1, 2, 3 or 5 min, …
Estimation of radiofrequency power leakage from microwave ovens for dosimetric assessment at nonionizing radiation exposure levels.
PMID: Biomed Res Int. 2015 ;2015:603260. Epub 2015 Feb 1. PMID: 25705676 Abstract Title: Estimation of radiofrequency power leakage from microwave ovens for dosimetric assessment at nonionizing radiation exposure levels. Abstract: The electromagnetic field leakage levels of nonionizing radiation from a microwave oven have been estimated within a complex indoor scenario. By employing a hybrid …
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