Bioavailable phytoprostanes and phytofurans from Gracilaria Longissima have anti-inflammatory effects in endothelial cells.

PMID:  Food Funct. 2020 May 20. Epub 2020 May 20. PMID: 32432610 Abstract Title:  Bioavailable phytoprostanes and phytofurans from Gracilaria longissima have anti-inflammatory effects in endothelial cells. Abstract:  BACKGROUND: An array of bioactive compounds with health-promoting effects has been described in several species of macroalgae. Among them, phytoprostanes (PhytoPs) and phytofurans (PhytoFs), both autoxidation products …

Sulfated polysaccharide from the red algae Gelidiella Acerosa: anticoagulant, antiplatelet and antithrombotic effects.

PMID:  Int J Biol Macromol. 2020 May 6. Epub 2020 May 6. PMID: 32387607 Abstract Title:  Sulfated polysaccharide from the red algae Gelidiella acerosa: Anticoagulant, antiplatelet and antithrombotic effects. Abstract:  A sulfated polysaccharide from the red algae Gelidiella acerosa (GaSP) was obtained through enzymatic extraction and subjected to chemical characterization by HPSEC, elemental microanalysis, FT-IR …

Alleviation effects of Bifidobacterium breve on DSS-induced colitis.

PMID:  Eur J Nutr. 2020 Apr 29. Epub 2020 Apr 29. PMID: 32350653 Abstract Title:  Alleviation effects of Bifidobacterium breve on DSS-induced colitis depends on intestinal tract barrier maintenance and gut microbiota modulation. Abstract:  PURPOSE: The study aimed to investigate the discrepancy and potential mechanisms of different CLA-producing B. breve on dextran sulphate sodium (DSS)-induced …

Anti-cancer effects of bifidobacterium species in colon cancer cells and a mouse model of carcinogenesis.

PMID:  PLoS One. 2020 ;15(5):e0232930. Epub 2020 May 13. PMID: 32401801 Abstract Title:  Anti-cancer effects of Bifidobacterium species in colon cancer cells and a mouse model of carcinogenesis. Abstract:  INTRODUCTION: Probiotics are suggested to prevent colorectal cancer (CRC). This study aimed to investigate the anticancer properties of some potential probiotics in vitro and in vivo.MATERIALS …

Activity of and effect of subcutaneous treatment with the broad-spectrum antiviral lectin griffithsin in two laboratory rodent models.

PMID:  Antimicrob Agents Chemother. 2014 ;58(1):120-7. Epub 2013 Oct 21. PMID: 24145548 Abstract Title:  Activity of and effect of subcutaneous treatment with the broad-spectrum antiviral lectin griffithsin in two laboratory rodent models. Abstract:  Griffithsin (GRFT) is a red-alga-derived lectin that binds the terminal mannose residues of N-linked glycans found on the surface of human immunodeficiency …

Combinations of griffithsin with other carbohydrate-binding agents demonstrate superior activity against HIV type 1, HIV type 2.

PMID:  AIDS Res Hum Retroviruses. 2012 Nov ;28(11):1513-23. Epub 2012 Jun 25. PMID: 22607556 Abstract Title:  Combinations of griffithsin with other carbohydrate-binding agents demonstrate superior activity against HIV Type 1, HIV Type 2, and selected carbohydrate-binding agent-resistant HIV Type 1 strains. Abstract:  Carbohydrate-binding agents (CBAs) are potential HIV microbicidal agents with a high genetic barrier …

Griffithsin, a potent HIV entry inhibitor, is an excellent candidate for anti-HIV microbicide.

PMID:  J Med Primatol. 2007 Aug ;36(4-5):244-53. PMID: 17669213 Abstract Title:  Griffithsin, a potent HIV entry inhibitor, is an excellent candidate for anti-HIV microbicide. Abstract:  BACKGROUND: The predominant mode of HIV-1 transmission is by heterosexual contact. The cervical/vaginal mucosa is the main port of HIV entry in women. A safe and effective topical microbicide against …

Seaweed secondary metabolites with beneficial health effects.

PMID:  Mar Drugs. 2019 Dec 20 ;18(1). Epub 2019 Dec 20. PMID: 31861879 Abstract Title:  Seaweed Secondary Metabolites with Beneficial Health Effects: An Overview of Successes in In Vivo Studies and Clinical Trials. Abstract:  Macroalgae are increasingly viewed as a source of secondary metabolites with great potential for the development of new drugs. In this …

Synergistic activity profile of griffithsin in combination with tenofovir, maraviroc and enfuvirtide against HIV-1 clade C.

PMID:  Virology. 2011 Sep 1 ;417(2):253-8. Epub 2011 Jul 28. PMID: 21802104 Abstract Title:  Synergistic activity profile of griffithsin in combination with tenofovir, maraviroc and enfuvirtide against HIV-1 clade C. Abstract:  Griffithsin (GRFT) is possibly the most potent anti-HIV peptide found in natural sources. Due to its potent and broad-spectrum antiviral activity and unique safety …

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