Tanshinone IIA inhibits oral squamous cell carcinoma via reducing Akt-c-Myc signaling-mediated aerobic glycolysis

PMID:  Cell Death Dis. 2020 May 18 ;11(5):381. Epub 2020 May 18. PMID: 32424132 Abstract Title:  Tanshinone IIA inhibits oral squamous cell carcinoma via reducing Akt-c-Myc signaling-mediated aerobic glycolysis. Abstract:  Aerobic glycolysis is one of the hallmarks of human cancer cells. Overexpression of hexokinase 2 (HK2) plays a crucial role in the maintaining of unlimited …

Honokiol reduces fungal load and inflammatory cytokines in aspergillus fumigatus keratitis.

PMID:  Invest Ophthalmol Vis Sci. 2020 Apr 9 ;61(4):48. PMID: 32347916 Abstract Title:  Honokiol Reduces Fungal Load, Toll-Like Receptor-2, and Inflammatory Cytokines in Aspergillus fumigatus Keratitis. Abstract:  Purpose: We characterized the effects of Honokiol (HNK) on Aspergillus fumigatus-caused keratomycosis and the underlying mechanisms. HNK is known to have anti-inflammatory and antifungal properties, but the influence …

Honokiol inhibits carotid artery atherosclerotic plaque formation by suppressing inflammation and oxidative stress.

PMID:  Aging (Albany NY). 2020 May 4 ;12. Epub 2020 May 4. PMID: 32365054 Abstract Title:  Honokiol inhibits carotid artery atherosclerotic plaque formation by suppressing inflammation and oxidative stress. Abstract:  Honokiol is a natural active compound extracted from Chinese herbal medicine,. In this study, the role of honokiol in the development of carotid artery atherosclerotic …

Magnolia extract is effective for the chemoprevention of oral cancer through its ability to inhibit mitochondrial respiration at complex I

PMID:  Cell Commun Signal. 2020 Apr 7 ;18(1):58. Epub 2020 Apr 7. PMID: 32264893 Abstract Title:  Magnolia extract is effective for the chemoprevention of oral cancer through its ability to inhibit mitochondrial respiration at complex I. Abstract:  BACKGROUND: Magnolia extract (ME) is known to inhibit cancer growth and metastasis in several cell types in vitro …

Magnolol-inhibited progression of colorectal cancer.

PMID:  Int J Mol Sci. 2020 May 16 ;21(10). Epub 2020 May 16. PMID: 32429376 Abstract Title:  Suppression of PKCδ/NF-κB Signaling and Apoptosis Induction through Extrinsic/Intrinsic Pathways Are Associated Magnolol-Inhibited Tumor Progression in Colorectal Cancer In Vitro and In Vivo. Abstract:  Magnolol is one of the hydroxylated biphenyl compounds from the root and stem bark …

This study intends to provide reference for clinical use of traditional Chinese medicine to resist new coronavirus.

PMID:  Zhongguo Zhong Yao Za Zhi. 2020 Mar ;45(6):1225-1231. PMID: 32281329 Abstract Title:  [Study on treatment of"cytokine storm"by anti-2019-nCoV prescriptions based on arachidonic acid metabolic pathway]. Abstract:  Since the outbreak of 2019-nCoV, the epidemic has developed rapidly and the situation is grim. LANCET figured out that the 2019-nCoV is closely related to"cytokine storm"."Cytokine storm" is …

Astaxanthin treatment induces maturation and functional change of myeloid-derived suppressor cells in tumor-bearing mice.

PMID:  Antioxidants (Basel). 2020 Apr 23 ;9(4). Epub 2020 Apr 23. PMID: 32340271 Abstract Title:  Astaxanthin Treatment Induces Maturation and Functional Change of Myeloid-Derived Suppressor Cells in Tumor-Bearing Mice. Abstract:  Myeloid-derived suppressor cells (MDSCs) are immature myeloid cells which accumulate in stress conditions such as infection and tumor. Astaxanthin (ATX) is a well-known antioxidant agent …

Clinical applications of astaxanthin in the treatment of ocular diseases.

PMID:  Mar Drugs. 2020 May 1 ;18(5). Epub 2020 May 1. PMID: 32370045 Abstract Title:  Clinical Applications of Astaxanthin in the Treatment of Ocular Diseases: Emerging Insights. Abstract:  Astaxanthin is a naturally occurring red carotenoid pigment belonging to the family of xanthophylls, and is typically found in marine environments, especially in microalgae and seafood such …

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