Ellagic acid and human cancers: a systems pharmacology and docking study.

PMID:  Mol Divers. 2020 May 14. Epub 2020 May 14. PMID: 32410114 Abstract Title:  Ellagic acid and human cancers: a systems pharmacology and docking study to identify principal hub genes and main mechanisms of action. Abstract:  Research on anticancer properties of natural compounds, as effective materials that are available while causing minimal side effects, is …

A herbal mixture from propolis, pomegranate, and grape pomace endowed with anti-inflammatory activity in an in vivo rheumatoid arthritis model.

PMID:  Molecules. 2020 May 11 ;25(9). Epub 2020 May 11. PMID: 32403241 Abstract Title:  A Herbal Mixture from Propolis, Pomegranate, and Grape Pomace Endowed with Anti-Inflammatory Activity in an In Vivo Rheumatoid Arthritis Model. Abstract:  Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease characterized by the production of inflammatory factors. In order to overcome …

Phenolic-rich pomegranate peel extract is evidenced as a safe herbal derived material promising for skin hyperpigmentation treatment.

PMID:  Planta Med. 2020 May 19. Epub 2020 May 19. PMID: 32428937 Abstract Title:  Phenolic-rich Pomegranate Peel Extract: In Vitro, Cellular, and In Vivo Activities for Skin Hyperpigmentation Treatment. Abstract:  The pomegranate phenolics are reported to have cutaneous benefits and to be effective in treating skin disorders, including hyperpigmentation. In this context, a preparation method …

Berberine might attenuate the liver inflammatory response in the livers of rats with high-fat diet-induced NAFLD.

PMID:  BMC Immunol. 2020 May 19 ;21(1):28. Epub 2020 May 19. PMID: 32429849 Abstract Title:  Anti-inflammatory activity of berberine in non-alcoholic fatty liver disease via the Angptl2 pathway. Abstract:  BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) has become the most common liver disease worldwide. Recent studies have shown that the Angptl2 pathway mediated hepatic inflammatory response …

Fingolimod in combination with berberine at reduced doses represents a novel therapy for ulcerative colitis.

n/a PMID:  J Nat Prod. 2020 May 20. Epub 2020 May 20. PMID: 32432470 Abstract Title:  Anti-inflammatory Efficacy of Combined Natural Alkaloid Berberine and S1PR Modulator Fingolimod at Low Doses in Ulcerative Colitis Preclinical Models. Abstract:  The natural alkaloid berberine is being studied as a drug candidate for the treatment of ulcerative colitis (UC). Fingolimod …

The antibacterial effect of silver nanoparticles on Staphylococcus epidermidis strains with different biofilm-forming ability.

PMID:  Nanomaterials (Basel). 2020 May 25 ;10(5). Epub 2020 May 25. PMID: 32466299 Abstract Title:  The Antibacterial Effect of Silver Nanoparticles on Staphylococcus epidermidis Strains with Different Biofilm-Forming Ability. Abstract:  Among many infectious diseases, infections caused by pathogens ofspecies exert a substantial influence upon human health, mainly due to their continuous presence on human skin …

AMPK and its activator berberine in the treatment of neurodegenerative diseases.

PMID:  Curr Pharm Des. 2020 May 23. Epub 2020 May 23. PMID: 32445451 Abstract Title:  AMPK and its activator Berberine in the Treatment of Neurodegenerative Diseases. Abstract:  Neurodegenerative disorders are heterogeneous diseases associated with either acute or progressive neurodegeneration, causing the loss of neurons and axons in the central nervous system (CNS), showing high morbidity …

Punicalagin played an important role in the attenuation of LPS-induced inflammatory responses in RAW264.7 macrophages.

n/a PMID:  Nutrients. 2019 Nov 15 ;11(11). Epub 2019 Nov 15. PMID: 31731808 Abstract Title:  Punicalagin Prevents Inflammation in LPS-Induced RAW264.7 Macrophages by Inhibiting FoxO3a/Autophagy Signaling Pathway. Abstract:  Punicalagin, a hydrolysable tannin of pomegranate juice, exhibits multiple biological effects, including inhibiting production of pro-inflammatory cytokines in macrophages. Autophagy, an intracellular self-digestion process, has been recently …

Advances on natural polyphenols as anticancer agents for skin cancer.

PMID:  Pharmacol Res. 2020 01 ;151:104584. Epub 2019 Dec 3. PMID: 31809853 Abstract Title:  Advances on Natural Polyphenols as Anticancer Agents for Skin Cancer. Abstract:  Polyphenols are one of most important phytochemicals distributing in herb plants, vegetables and fruits, which known as important anticancer agents. Given the high incidence and mortality of skin cancer, this …

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