Blueberry polyphenols play a preventive effect on alcoholic fatty liver disease.

PMID:  Ann Palliat Med. 2020 May 7. Epub 2020 May 7. PMID: 32389004 Abstract Title:  Blueberry polyphenols play a preventive effect on alcoholic fatty liver disease C57BL/6 J mice by promoting autophagy to accelerate lipolysis to eliminate excessive TG accumulation in hepatocytes. Abstract:  BACKGROUND: This study aims to explore blueberry polyphenols and its roles in …

Blueberry-derived exosome-like nanoparticles counter the response to TNF-α-induced change on gene expression in EA.hy926 cells.

PMID:  Biomolecules. 2020 May 10 ;10(5). Epub 2020 May 10. PMID: 32397678 Abstract Title:  Blueberry-Derived Exosome-Like Nanoparticles Counter the Response to TNF-α-Induced Change on Gene Expression in EA.hy926 Cells. Abstract:  Exosome-like nanoparticles (ELNs) are attracting interest as important vehicles of intercellular communication, both in prokaryotes and eukaryotes. Recently, dietary nanoparticles similar to mammalian exosomes have …

Chemoprotective effect of carotenoids from Lycium barbarum L. on SH-SY5Y neuroblastoma cells treated with beauvericin.

PMID:  Food Chem Toxicol. 2020 May 6 ;141:111414. Epub 2020 May 6. PMID: 32387444 Abstract Title:  Chemoprotective effect of carotenoids from Lycium barbarum L. on SH-SY5Y neuroblastoma cells treated with beauvericin. Abstract:  Goji berry has recently been introduced in Mediterranean diet and its consumption is increasing. This study aims to determine cytoprotection of lutein (LUT), …

Lycium barbarum polysaccharide may improve allergic asthma by altering gut microbiota and inhibiting inflammation in mice.

PMID:  J Med Food. 2020 May 11. Epub 2020 May 11. PMID: 32392444 Abstract Title:  Polysaccharide Extracted fromLeaves Ameliorates Asthma in Mice by Reducing Inflammation and Modulating Gut Microbiota. Abstract:  This study was designed to explore the impact ofpolysaccharide (LBP) on inflammation and gut microbiota in mice with allergic asthma. Mice were divided into four …

MicroRNAs and exosomes: key players in HIV pathogenesis.

PMID:  HIV Med. 2020 Apr ;21(4):246-278. Epub 2019 Nov 22. PMID: 31756034 Abstract Title:  MicroRNAs and exosomes: key players in HIV pathogenesis. Abstract:  OBJECTIVES: HIV infection is well known to cause impairment of the human immune system, and until recently was a leading cause of death. It has been shown that T lymphocytes are the …

Exosomes cloak the virion to transmit Enterovirus 71 non-lytically.

PMID:  Virulence. 2020 Dec ;11(1):32-38. PMID: 31885311 Abstract Title:  Exosomes cloak the virion to transmit Enterovirus 71 non-lytically. Abstract:  Enterovirus 71 (EV71) is a non-enveloped virus and it can be released from host cells through a traditional cytolytic manner. Now, we showed EV71 could be spread non-lytically between cells during early viral infection. In order …

Where does the cargo go?: Solutions to provide experimental support for the “extracellular vesicle cargo transfer hypothesis”.

PMID:  J Cell Commun Signal. 2020 Feb 14. Epub 2020 Feb 14. PMID: 32060725 Abstract Title:  Where does the cargo go?: Solutions to provide experimental support for the"extracellular vesicle cargo transfer hypothesis". Abstract:  It is widely believed that extracellular vesicles (EVs) mediate intercellular communications by functioning as messengers. EVs contain various biomolecules, including nucleic acids …

Extracellular vesicles in Epstein-barr virus pathogenesis.

PMID:  Curr Clin Microbiol Rep. 2019 Sep ;6(3):121-131. Epub 2019 Jul 3. PMID: 32051811 Abstract Title:  Extracellular Vesicles in Epstein-Barr Virus Pathogenesis. Abstract:  Purpose of review: Epstein-Barr virus (EBV) is a known determinant for numerous malignancies and may contribute to autoimmune diseases. The underlining mechanisms behind EBV pathologies is not completely understood. Recently, extracellular vesicles …

Exosomes may cause immunosuppression and immune tolerance.

PMID:  Int J Biol Sci. 2020 ;16(6):904-920. Epub 2020 Jan 22. PMID: 32140061 Abstract Title:  Exosomes Transmit Viral Genetic Information and Immune Signals may cause Immunosuppression and Immune Tolerance in ALV-J Infected HD11 cells. Abstract:  Avian leukosis virus (ALV) is oncogenic retrovirus that not only causes immunosuppression but also enhances the host's susceptibility to secondary …

hnRNPA2B1 associated with recruitment of RNA into exosomes plays a key role in HSV-1 release from infected cells.

PMID:  J Virol. 2020 Apr 15. Epub 2020 Apr 15. PMID: 32295924 Abstract Title:  hnRNPA2B1 associated with recruitment of RNA into exosomes plays a key role in HSV-1 release from infected cells. Abstract:  hnRNPA2B1, an abundant cellular protein has been reported to recruit RNAs bearing a specific sequence (EXO motif) into exosomes. We characterized an …

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