Cannabinoids as anticancer therapeutic agents.

PMID:  Cell Cycle. 2020 May ;19(9):961-989. Epub 2020 Apr 5. PMID: 32249682 Abstract Title:  Cannabinoids as anticancer therapeutic agents. Abstract:  The recent announcement of marijuana legalization in Canada spiked many discussions about potential health benefits of. Cannabinoids are active chemical compounds produced by cannabis, and their numerous effects on the human body are primarily exerted …

Synergistic cytotoxic activity of cannabinoids from cannabis sativa against cutaneous T-cell lymphoma.

PMID:  Oncotarget. 2020 Mar 31 ;11(13):1141-1156. Epub 2020 Mar 31. PMID: 32284791 Abstract Title:  Synergistic cytotoxic activity of cannabinoids fromagainst cutaneous T-cell lymphoma (CTCL)and. Abstract:  produces hundreds of phytocannabinoids and terpenes. Mycosis fungoides (MF) is the most common type of cutaneous T-cell lymphoma (CTCL), characterized by patches, plaques and tumors. Sézary is a leukemic stage …

Cannabis may have a beneficial impact on HIV-associated blood-brain barrier injury.

PMID:  Clin Infect Dis. 2020 Apr 16. Epub 2020 Apr 16. PMID: 32296832 Abstract Title:  Beneficial Effects of Cannabis on Blood Brain Barrier Function in HIV. Abstract:  BACKGROUND: HIV infection leads to blood-brain barrier (BBB) dysfunction that does not resolve despite viral suppression on antiretroviral therapy and is associated with adverse clinical outcomes. In preclinical …

Cannabis for symptom management in older adults.

PMID:  Med Clin North Am. 2020 May ;104(3):471-489. PMID: 32312410 Abstract Title:  Cannabis for Symptom Management in Older Adults. Abstract:  The purpose of this article is to present evidence on the efficacy and safety of medical cannabis as a therapy for symptom management in palliative care. This article provides an overview of the evidence on …

Cannabis and cannabinoids in cancer pain management.

PMID:  Curr Opin Support Palliat Care. 2020 Jun ;14(2):87-93. PMID: 32332209 Abstract Title:  Cannabis and cannabinoids in cancer pain management. Abstract:  PURPOSE OF REVIEW: An increasing number of patients are turning to cannabis and cannabinoids for management of their palliative and nonpalliative cancer pain and other cancer-related symptoms. Canadians have a legal framework for access …

Naringin induces lysosomal permeabilization and autophagy cell death in AGS gastric cancer cells.

PMID:  Am J Chin Med. 2020 ;48(3):679-702. Epub 2020 Apr 24. PMID: 32329644 Abstract Title:  Naringin Induces Lysosomal Permeabilization and Autophagy Cell Death in AGS Gastric Cancer Cells. Abstract:  Autophagy is a process of active programmed cell death, where a dying cell induces autophagosomes and subsequently regulated by degradative machinery. The aim of this study …

Naringin induces endoplasmic reticulum stress-mediated apoptosis, inhibits β-catenin pathway and arrests cell cycle in cervical cancer cells.

PMID:  Acta Biochim Pol. 2020 Apr 28. Epub 2020 Apr 28. PMID: 32343512 Abstract Title:  Naringin induces endoplasmic reticulum stress-mediated apoptosis, inhibitsβ-catenin pathway and arrests cell cycle in cervical cancer cells. Abstract:  Naringin is a promising anticancer bioflavonoid phytochemical, mainly extracted from citrus fruits. This study evaluates the antiproliferative effect and the cell death mechanism …

Naringin inhibits colorectal cancer cell growth.

PMID:  Exp Ther Med. 2020 Jun ;19(6):3798-3804. Epub 2020 Apr 7. PMID: 32346444 Abstract Title:  Naringin inhibits colorectal cancer cell growth by repressing the PI3K/AKT/mTOR signaling pathway. Abstract:  In recent years, the incidence of colorectal cancer (CRC) has increased and research into new treatment methods for CRC has become a hot topic. Naringin has an …

The genoprotective role of naringin.

PMID:  Biomolecules. 2020 Apr 30 ;10(5). Epub 2020 Apr 30. PMID: 32365989 Abstract Title:  The Genoprotective Role of Naringin. Abstract:  Since ancient times, fruits and edible plants have played a special role in the human diet for enhancing health and maintaining youthfulness. The aim of our work was to determine the interactions between naringin, a …

Naringenin regulates doxorubicin-induced liver dysfunction.

PMID:  Plants (Basel). 2020 Apr 24 ;9(4). Epub 2020 Apr 24. PMID: 32344607 Abstract Title:  Naringenin Regulates Doxorubicin-Induced Liver Dysfunction: Impact on Oxidative Stress and Inflammation. Abstract:  Doxorubicin (Dox) is an operational and largely used anticancer drug, used to treat an array of malignancies. Nonetheless, its beneficial use is constrained due to its renal and …

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