PMID: In Vivo. 2020 May-Jun;34(3):1077-1084. PMID: 32354895 Abstract Title: Wogonin Influences Osteosarcoma Stem Cell Stemness Through ROS-dependent Signaling. Abstract: : Backgorund/Aim: Wogonin, a flavonoid-like compound extracted from the root of Scutellaria baicalensis Georgi, has been shown to have anticancer effects against cancer cells. Osteosarcoma is the most malignant type of bone cancer and can appear …
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Rosmarinic acid alleviates ethanol-induced lipid accumulation by repressing fatty acid biosynthesis.
PMID: Food Funct. 2020 Mar 1 ;11(3):2094-2106. Epub 2020 Mar 4. PMID: 32129352 Abstract Title: Rosmarinic acid alleviates ethanol-induced lipid accumulation by repressing fatty acid biosynthesis. Abstract: Recent studies have demonstrated that rosmarinic acid is a valuable natural product for treatment of alcoholic liver disease. However, the mechanisms whereby rosmarinic acid improves alcoholic liver disease …
A review of the anti-inflammatory effects of rosmarinic acid on inflammatory diseases.
PMID: Front Pharmacol. 2020 ;11:153. Epub 2020 Feb 28. PMID: 32184728 Abstract Title: A Review of the Anti-Inflammatory Effects of Rosmarinic Acid on Inflammatory Diseases. Abstract: Inflammatory diseases are caused by abnormal immune responses and are characterized by an imbalance of inflammatory mediators and cells. In recent years, the anti-inflammatory activity of natural products has …
Nephroprotective effect of green tea, rosmarinic acid and rosemary on N-diethylnitrosamine initiated and ferric nitrilotriacetate promoted acute renal toxicity.
PMID: Interdiscip Toxicol. 2019 Oct ;12(2):98-110. Epub 2020 Feb 20. PMID: 32206031 Abstract Title: Nephroprotective effect of green tea, rosmarinic acid and rosemary on N-diethylnitrosamine initiated and ferric nitrilotriacetate promoted acute renal toxicity in Wistar rats. Abstract: The present study was designed to investigate the chemoprotective effect of green tea extract (GTE), rosmarinic acid (RA) …
Rosmarinic acid exerts a neuroprotective effect on spinal cord injury.
PMID: Toxicol Appl Pharmacol. 2020 Apr 19 ;397:115014. Epub 2020 Apr 19. PMID: 32320792 Abstract Title: Rosmarinic acid exerts a neuroprotective effect on spinal cord injury by suppressing oxidative stress and inflammation via modulating the Nrf2/HO-1 and TLR4/NF-κB pathways. Abstract: Spinal cord injury (SCI) is a severe central nervous system injury for which few efficacious …
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Vitamin D Deficiency in Pregnancy Linked to Higher ADHD Risk in Children
Research shows that the value of optimal vitamin D levels in the body cannot be emphasized enough, especially among pregnant women
Carvacrol suppresses learning and memory dysfunction and hippocampal damages caused by chronic cerebral hypoperfusion.
PMID: Naunyn Schmiedebergs Arch Pharmacol. 2020 04 ;393(4):581-589. Epub 2019 Nov 15. PMID: 31729545 Abstract Title: Carvacrol suppresses learning and memory dysfunction and hippocampal damages caused by chronic cerebral hypoperfusion. Abstract: Chronic cerebral hypoperfusion (CCH) is a common phenomenon in many neurological diseases such as vascular dementia and Alzheimer's disease. Several drugs have been investigated …
Co-administration of curcumin or carvacrol and doxorubicin for 24 days could improve the heart function and structural changes.
PMID: Food Sci Nutr. 2019 Nov ;7(11):3581-3588. Epub 2019 Sep 10. PMID: 31763008 Abstract Title: Cardioprotective effects of curcumin and carvacrol in doxorubicin-treated rats: Stereological study. Abstract: Doxorubicin (DOX) is a cardiotoxic drug. To reduce the harmful effects of DOX, two plant-derived components, including curcumin (CUR) and carvacrol (CAR), were considered. This study aimed to …
Enhancement in site-specific delivery of carvacrol against methicillin resistant Staphylococcus aureus induced skin infections.
PMID: Pharmaceutics. 2019 Nov 13 ;11(11). Epub 2019 Nov 13. PMID: 31766227 Abstract Title: Enhancement in Site-Specific Delivery of Carvacrol against Methicillin ResistantInduced Skin Infections Using Enzyme Responsive Nanoparticles: A Proof of Concept Study. Abstract: Methicillin resistant(MRSA) induced skin infections have become a challenging problem due to the escalating antibiotic resistance. Carvacrol (CAR) has been …
The results indicated that carvacrol protected from learning and memory impairment and the brain tissue inflammation and oxidative stress.
PMID: Neurotox Res. 2020 Apr ;37(4):965-976. Epub 2019 Dec 6. PMID: 31811590 Abstract Title: Protective Effects of Carvacrol on Brain Tissue Inflammation and Oxidative Stress as well as Learning and Memory in Lipopolysaccharide-Challenged Rats. Abstract: Inflammation can cause memory impairment. In the present study, the effect of carvacrol on brain tissue inflammation and oxidative stress …
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