PMID: J Ayurveda Integr Med. 2020 May 16. Epub 2020 May 16. PMID: 32430240 Abstract Title: Pomegranate-derived anthocyanin regulates MORs-cAMP/CREB-BDNF pathways in opioid-dependent models and improves cognitive impairments. Abstract: BACKGROUND: Pomegranate (Punica granatum) is one of the oldest known edible fruit. Recently, there has been an increased interest in this fruit as a functional food …
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Punicalagin played an important role in the attenuation of LPS-induced inflammatory responses in RAW264.7 macrophages.
n/a PMID: Nutrients. 2019 Nov 15 ;11(11). Epub 2019 Nov 15. PMID: 31731808 Abstract Title: Punicalagin Prevents Inflammation in LPS-Induced RAW264.7 Macrophages by Inhibiting FoxO3a/Autophagy Signaling Pathway. Abstract: Punicalagin, a hydrolysable tannin of pomegranate juice, exhibits multiple biological effects, including inhibiting production of pro-inflammatory cytokines in macrophages. Autophagy, an intracellular self-digestion process, has been recently …
Advances on natural polyphenols as anticancer agents for skin cancer.
PMID: Pharmacol Res. 2020 01 ;151:104584. Epub 2019 Dec 3. PMID: 31809853 Abstract Title: Advances on Natural Polyphenols as Anticancer Agents for Skin Cancer. Abstract: Polyphenols are one of most important phytochemicals distributing in herb plants, vegetables and fruits, which known as important anticancer agents. Given the high incidence and mortality of skin cancer, this …
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Pomegranate as a aource of bioactive constituents: a review on their characterization, properties and applications.
PMID: Crit Rev Food Sci Nutr. 2020 Apr 21:1-18. Epub 2020 Apr 21. PMID: 32314615 Abstract Title: Pomegranate as a source of bioactive constituents: a review on their characterization, properties and applications. Abstract: Increasing awareness about the use of compounds obtained from natural sources exerting health-beneficial properties, including antimicrobial and antioxidant effects, led to increased …
Punicalagin inhibits the viability, migration, invasion, and EMT by regulating GOLPH3 in breast cancer cells.
PMID: J Recept Signal Transduct Res. 2020 Apr ;40(2):173-180. Epub 2020 Feb 6. PMID: 32024401 Abstract Title: Punicalagin inhibits the viability, migration, invasion, and EMT by regulating GOLPH3 in breast cancer cells. Abstract: Breast cancer (BC) is one of the most common malignancies worldwide. Punicalagin (PN), which is a type of polyphenol, has been reported …
Punicalagin promotes the apoptosis in human cervical cancer.
PMID: Saudi J Biol Sci. 2020 Apr ;27(4):1100-1106. Epub 2020 Mar 4. PMID: 32256171 Abstract Title: Punicalagin promotes the apoptosis in human cervical cancer (ME-180) cells through mitochondrial pathway and by inhibiting the NF-kB signaling pathway. Abstract: Increasing attention of plant derived therapeutic agents against cancer, investigating the anti-proliferative efficiency of plant derived chemicals have …
Continue reading “Punicalagin promotes the apoptosis in human cervical cancer.”
Pomegranate-derived anthocyanin regulates MORs-cAMP/CREB-BDNF pathways in opioid-dependent models and improves cognitive impairments.
PMID: J Ayurveda Integr Med. 2020 May 16. Epub 2020 May 16. PMID: 32430240 Abstract Title: Pomegranate-derived anthocyanin regulates MORs-cAMP/CREB-BDNF pathways in opioid-dependent models and improves cognitive impairments. Abstract: BACKGROUND: Pomegranate (Punica granatum) is one of the oldest known edible fruit. Recently, there has been an increased interest in this fruit as a functional food …
Punicalagin protects diabetic nephropathy.
PMID: Nutrients. 2020 May 22 ;12(5). Epub 2020 May 22. PMID: 32456088 Abstract Title: Punicalagin Protects Diabetic Nephropathy by Inhibiting Pyroptosis Based on TXNIP/NLRP3 Pathway. Abstract: Diabetic nephropathy is a diabetic complication caused by chronic inflammation. As the primary polyphenol in pomegranate, punicalagin is believed to have significant anti-inflammatory properties. In this study, we established …
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Natural plant extract berbamine is a potent inhibitor of cell growth and survival of human tenon’s fibroblasts.
PMID: Ophthalmic Res. 2020 Feb 20. Epub 2020 Feb 20. PMID: 32079013 Abstract Title: Natural plant extract Berbamine is a potent inhibitor of cell growth and survival of human Tenon's fibroblasts. Abstract: INTRODUCTION: Post-trabeculectomy scaring due to excessive proliferation of human Tenon's fibroblasts (HTFs) often led to operation failure. Developing a new anti-fibrosis drug with …
Berbamine ameliorates ethanol-induced liver injury by inhibition of hepatic inflammation.
PMID: Chin J Nat Med. 2020 Mar ;18(3):186-195. PMID: 32245588 Abstract Title: Berbamine ameliorates ethanol-induced liver injury by inhibition of hepatic inflammation in mice. Abstract: Alcoholic liver disease (ALD) has become one of the leading causes of death in the world. Berbamine (BM), a natural product mainly derived from Berberis vulgaris L, possesses multiple bioactivities …
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