Category Archives: Uncategorized

PMID:  Chronic Dis Transl Med. 2018 Dec ;4(4):211-224. Epub 2018 Dec 18. PMID: 30603740 Abstract Title:  Tomato lycopene prevention of alcoholic fatty liver disease and hepatocellular carcinoma development. Abstract:  Alcoholic liver disease (ALD) is a major cause of morbidity and mortality worldwide. The incidence of hepatocellular carcinoma (HCC) is increasing in the United States, and chronic, …

Continue reading “Tomato lycopene prevention of alcoholic fatty liver disease and hepatocellular carcinoma development.”

PMID:  Neuroimmunomodulation. 2019 ;26(2):84-92. Epub 2019 Jan 9. PMID: 30625493 Abstract Title:  Anti-Inflammatory Effect of Lycopene on Experimental Spinal Cord Ischemia Injury via Cyclooxygenase-2 Suppression. Abstract:  OBJECTIVE: Spinal cord ischemia/reperfusion injury (SCII) is a devastating complication following thoracoabdominal aortic surgeries, often leading to severe neurological deficits. We sought to examine the effects of lycopene, a …

Continue reading “Lycopene exerted neuroprotective functions in Spinal cord ischemia/reperfusion injury and inhibited its elicited neuroinflammation via COX-2 suppression.”

PMID:  J Nutr Biochem. 2019 03 ;65:93-100. Epub 2018 Dec 21. PMID: 30660958 Abstract Title:  Lycopene mitigates pulmonary emphysema induced by cigarette smoke in a murine model. Abstract:  Chronic obstructive pulmonary disease (COPD) is an inflammatory lung disease characterized by a non-fully reversible airflow limitation comprising chronic bronchitis and pulmonary emphysema both being induced by …

Continue reading “Lycopene mitigates pulmonary emphysema induced by cigarette smoke in a murine model.”

PMID:  Epilepsy Res. 2019 03 ;151:1-6. Epub 2019 Jan 17. PMID: 30669043 Abstract Title:  Protective effects of lycopene on kainic acid-induced seizures. Abstract:  Lycopene (LCP) is a carotenoid that protects against many diseases by alleviating oxidative stress. However, the effect of LCP on epileptic seizures has not been examined well in previous studies. In the …

Continue reading “Lycopene may be a potential functional food alternative for controlling and treating epileptic seizures.”

PMID:  J Indian Soc Periodontol. 2019 Jan-Feb;23(1):25-30. PMID: 30692739 Abstract Title:  Antioxidant therapy (lycopene and green tea extract) in periodontal disease: A promising paradigm. Abstract:  Background: Increased oxidative stress has emerged as one of the prime factors in the pathogenesis of periodontitis. Hence, antioxidant therapy may become a promising tool in the treatment of periodontal …

Continue reading “Lycopene with green tea extract may prove to be a promising adjunctive prophylactic and therapeutic modality in the treatment of gingivitis patients.”

PMID:  J Cancer. 2019 ;10(2):510-521. Epub 2019 Jan 1. PMID: 30719147 Abstract Title:  Lycopene upregulates ZO-1 and downregulates claudin-1 through autophagy inhibition in the human cutaneous squamous cell carcinoma cell line COLO-16. Abstract:  Lycopene, a kind of carotenoid, has been reported to have an inhibitory function on tumor cell migration. However, the potential role of …

Continue reading “This study indicates that lycopene might be a useful chemopreventive agent against cutaneous squamous cell carcinoma.”

PMID:  J Liposome Res. 2019 Feb 10:1-8. Epub 2019 Feb 10. PMID: 30741056 Abstract Title:  Enhanced antitumor efficacy and attenuated cardiotoxicity of doxorubicin in combination with lycopene liposomes. Abstract:  The aim of this study was to evaluate whether lycopene-loaded liposomes (L-LYC) could interfere with the antitumor efficacy and cardiotoxicity of doxorubicin (DOX). L-LYC were prepared …

Continue reading “Enhanced antitumor efficacy and attenuated cardiotoxicity of doxorubicin in combination with lycopene liposomes.”

PMID:  J Inorg Biochem. 2019 Apr ;193:143-151. Epub 2019 Feb 1. PMID: 30743053 Abstract Title:  Lycopene attenuates aluminum-induced hippocampal lesions by inhibiting oxidative stress-mediated inflammation and apoptosis in the rat. Abstract:  Aluminum (Al) causes hippocampal lesions by oxidative stress, which is widely accepted as the primary pathogenesis of Al neurotoxicity. Lycopene (LYC), a naturally carotenoid, …

Continue reading “Lycopene attenuates aluminum-induced hippocampal lesions by inhibiting oxidative stress-mediated inflammation.”

PMID:  J Nutr Biochem. 2019 Apr ;66:70-78. Epub 2019 Jan 7. PMID: 30772766 Abstract Title:  Lycopene protects against pressure overload-induced cardiac hypertrophy by attenuating oxidative stress. Abstract:  Oxidative stress is considered an important pathogenic process of cardiac hypertrophy. Lycopene is a kind of carotenoid antioxidant that protects the cardiovascular system, so we hypothesized that lycopene …

Continue reading “Lycopene protects against pressure overload-induced cardiac hypertrophy by attenuating oxidative stress.”

PMID:  Food Funct. 2019 Apr 17 ;10(4):1974-1984. PMID: 30889234 Abstract Title:  Lycopene inhibits hepatic stellate cell activation and modulates cellular lipid storage and signaling. Abstract:  Hepatic stellate cells are liver-specific perivascular cells, identified as the major source of collagen in liver fibrosis, following their activation and conversion to myofibroblast-like cells. Lycopene is a carotenoid with …

Continue reading “Lycopene inhibits hepatic stellate cell activation and modulates cellular lipid storage and signaling.”