Vitamin C deficiency and the injection of foreign proteins can cause a high blood histamine level, leading to capillary fragility and venular bleeding.

PMID:  Med Hypotheses. 2004 ;62(4):533-6. PMID: 15050101 Abstract Title:  Elevated blood histamine caused by vaccinations and Vitamin C deficiency may mimic the shaken baby syndrome. Abstract:  The findings of subdural hematoma and retinal hemorrhages in infants, without any documented history of major trauma, do not always indicate child abuse. A combination of ascorbate depletion and …

A case report of fatal infection due to the vaccine strain of the varicella-zoster virus in an adult following stem cell transplantation.

PMID:  Clin Infect Dis. 2015 Apr 1 ;60(7):1068-74. Epub 2014 Dec 1. PMID: 25452596 Abstract Title:  Disseminated, persistent, and fatal infection due to the vaccine strain of varicella-zoster virus in an adult following stem cell transplantation. Abstract:  Live attenuated varicella vaccine is recommended for healthy individuals who are susceptible to varicella. Although the vaccine is …

Consumption of a western pattern diet may be a risk factor for development of late age-related macular degeneration.

PMID:  Br J Ophthalmol. 2019 Dec 6. Epub 2019 Dec 6. PMID: 31810976 Abstract Title:  Diet patterns and the incidence of age-related macular degeneration in the Atherosclerosis Risk in Communities (ARIC) study. Abstract:  BACKGROUND: Age-related macular degeneration (AMD) is the leading cause of irreversible vision loss among the elderly.OBJECTIVE: This study aimed to determine the …

Neuroprotective exendin-4 enhances hypothermia therapy in a model of hypoxic-ischaemic encephalopathy.

PMID:  Brain. 2018 10 1 ;141(10):2925-2942. PMID: 30165597 Abstract Title:  Neuroprotective exendin-4 enhances hypothermia therapy in a model of hypoxic-ischaemic encephalopathy. Abstract:  Hypoxic-ischaemic encephalopathy remains a global health burden. Despite medical advances and treatment with therapeutic hypothermia, over 50% of cooled infants are not protected and still develop lifelong neurodisabilities, including cerebral palsy. Furthermore, hypothermia …

Astaxanthin: a potential mitochondrial-targeted antioxidant treatment in diseases and with aging.

PMID:  Oxid Med Cell Longev. 2019 ;2019:3849692. Epub 2019 Nov 11. PMID: 31814873 Abstract Title:  Astaxanthin: A Potential Mitochondrial-Targeted Antioxidant Treatment in Diseases and with Aging. Abstract:  Oxidative stress is characterized by an imbalance between prooxidant and antioxidant species, leading to macromolecular damage and disruption of redox signaling and cellular control. It is a hallmark …

Inhibition of Escherichia coli O157:H7 and Salmonella enterica virulence factors by benzyl isothiocyanate.

PMID:  Food Microbiol. 2020 Apr ;86:103303. Epub 2019 Aug 16. PMID: 31703885 Abstract Title:  Inhibition of Escherichia coli O157:H7 and Salmonella enterica virulence factors by benzyl isothiocyanate. Abstract:  Escherichia coli O157:H7 and Salmonella enterica are foodborne pathogens with major public health concern in the U.S. These pathogens utilize several virulence factors to initiate infections in …

This evidence provides a potential clinically relevant role for EGCG in delaying or treating human Parkinson’s disease.

PMID:  Neurotox Res. 2019 Dec 6. Epub 2019 Dec 6. PMID: 31811588 Abstract Title:  Protective Effect of (-)Epigallocatechin-3-gallate on Rotenone-Induced Parkinsonism-like Symptoms in Rats. Abstract:  Rotenone (ROT)-induced neurotoxicity has been used for decades as an animal model of Parkinson's disease (PD) in humans. This model exhibits pathophysiological features similar to those reported in patients with …

l-Theanine improves functional recovery after traumatic spinal cord injury in rats.

PMID:  J Formos Med Assoc. 2019 Dec 5. Epub 2019 Dec 5. PMID: 31812333 Abstract Title:  l-Theanine improves functional recovery after traumatic spinal cord injury in rats. Abstract:  BACKGROUND/PURPOSE: Spinal cord injury (SCI) is a devastating medical condition for which no effective pharmacological interventions exist. l-Theanine (LT), a major amino acid component of green tea, …

Genipin attenuates dextran sulfate sodium-induced colitis via suppressing inflammatory and oxidative responses.

PMID:  Inflammopharmacology. 2019 Oct 23. Epub 2019 Oct 23. PMID: 31646411 Abstract Title:  Genipin attenuates dextran sulfate sodium-induced colitis via suppressing inflammatory and oxidative responses. Abstract:  Genipin is one of the major component in Gardenis fruit, which has long been used in the treatment of many chronic diseases, such as colitis. In the present study, …

Protective effects of genipin on ethanol-induced acute gastric injury in mice by inhibiting NLRP3 inflammasome activation.

PMID:  Eur J Pharmacol. 2019 Dec 2:172800. Epub 2019 Dec 2. PMID: 31805268 Abstract Title:  Protective effects of genipin on ethanol-induced acute gastric injury in mice by inhibiting NLRP3 inflammasome activation. Abstract:  Genipin has been shown to exert anti-inflammatory effects, but its mechanism in protecting the ethanol-induced acute gastric injuries remains largely unclear. The present …

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