PMID: Pharmacol Res. 2019 Dec ;150:104476. Epub 2019 Oct 9. PMID: 31605783 Abstract Title: Resveratrol in experimental Alzheimer's disease models: A systematic review of preclinical studies. Abstract: Alzheimer's disease (AD) is a progressive dementia caused by degeneration of the central nervous system with a high incidence in the elderly. Resveratrol is a natural compound contained …
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Resveratrol induces immunogenic cell death of human and murine ovarian carcinoma cells.
PMID: Infect Agent Cancer. 2019 ;14:27. Epub 2019 Oct 18. PMID: 31636696 Abstract Title: Resveratrol induces immunogenic cell death of human and murine ovarian carcinoma cells. Abstract: Purpose: This study aimed to clarify whether immunogenic cell death (ICD) contributed to the anti-tumor action of resveratrol against ovarian carcinoma.Methods: Resveratrol suppressed cell proliferation and induced apoptosis …
Resveratrol ameliorates high-fat diet-induced insulin resistance and fatty acid oxidation.
PMID: Eur Rev Med Pharmacol Sci. 2019 Oct ;23(20):9117-9125. PMID: 31696503 Abstract Title: Resveratrol ameliorates high-fat diet-induced insulin resistance and fatty acid oxidation via ATM-AMPK axis in skeletal muscle. Abstract: OBJECTIVE: Resveratrol (RSV) is a polyphenolic phytoalexin that exhibits diverse pharmacological actions, including its effect on the insulin resistance. However, the mechanism through which RSV …
Effects of resveratrol on learning and memory in rats with vascular dementia.
PMID: Mol Med Rep. 2019 Nov ;20(5):4587-4593. Epub 2019 Oct 2. PMID: 31702039 Abstract Title: Effects of resveratrol on learning and memory in rats with vascular dementia. Abstract: The purpose of the present study was to study the effects of resveratrol on cognitive function in rats with vascular dementia and to investigate the molecular mechanisms …
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Resveratrol induces depletion of TRAF6 and suppresses prostate cancer cell proliferation and migration.
PMID: Int J Biochem Cell Biol. 2019 Nov 9 ;118:105644. Epub 2019 Nov 9. PMID: 31712163 Abstract Title: Resveratrol induces depletion of TRAF6 and suppresses prostate cancer cell proliferation and migration. Abstract: Although the early diagnosis of prostate cancer (PCa) enhances life expectancy with a 5-year survival rate of 100 %, metastasized-PCa is the fundamental …
These results suggest resveratrol has therapeutic effects in the treatment of atopic dermatitis.
PMID: Wounds. 2019 Nov ;31(11):279-284. Epub 2019 Sep 15. PMID: 31730508 Abstract Title: Resveratrol Exerts Therapeutic Effects on Mice With Atopic Dermatitis. Abstract: INTRODUCTION: Atopic dermatitis (AD) is a chronic inflammatory skin disease with a high prevalence in children worldwide. Resveratrol exerts various pharmacologic effects, and application of resveratrol has been suggested as an alternative …
Anti-breast cancer activity of resveratrol encapsulated in liposomes.
PMID: J Mater Chem B. 2019 Nov 20. Epub 2019 Nov 20. PMID: 31746932 Abstract Title: Anti-breast cancer activity of resveratrol encapsulated in liposomes. Abstract: Resveratrol (RES) is a naturally occurring and effective drug for tumor prevention and treatment. However, its low levels of aqueous solubility, stability, and poor bioavailability limit its application, especially when …
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Resveratrol treatment may be a promising preventive or supplemental measure for delaying or preventing the formation of age-related cataract.
PMID: J Biochem Mol Toxicol. 2019 Nov 20:e22420. Epub 2019 Nov 20. PMID: 31746523 Abstract Title: Resveratrol delay the cataract formation against naphthalene-induced experimental cataract in the albino rats. Abstract: Oxidative stress-induced toxicity plays a major role in ocular diseases such as retinal degeneration, age-related cataract (ARC) formation and macular dystrophy. In this study, we …
Resveratrol pretreatment alleviates myocardial ischemia/reperfusion injury.
PMID: J Physiol Biochem. 2019 Nov 30. Epub 2019 Nov 30. PMID: 31786730 Abstract Title: Resveratrol pretreatment alleviates myocardial ischemia/reperfusion injury by inhibiting STIM1-mediated intracellular calcium accumulation. Abstract: Previous studies have shown that stromal interaction molecule1 (STIM1)-mediated store-operated Caentry (SOCE) contributes to intracellular Caaccumulation in H9C2 cells subjected to hypoxia/reoxygenation(H/R) injury. The aim of the …
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Xanthohumol inhibits tau protein aggregation and protects cells against tau aggregates.
PMID: Food Funct. 2019 Dec 3. Epub 2019 Dec 3. PMID: 31793596 Abstract Title: Xanthohumol inhibits tau protein aggregation and protects cells against tau aggregates. Abstract: Alzheimer's disease (AD) is a neurodegenerative disease. The molecular mechanisms of AD are not yet clear, and no effective treatments are available to cure AD. Because of the huge …
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