PMID: Am J Public Health. 2012 Sep ;102(9):e13-4. Epub 2012 Jul 19. PMID: 22813421 Abstract Title: Who profits from uncritical acceptance of biased estimates of vaccine efficacy and safety? Abstract: [n/a] read more
Category Archives: Uncategorized
High vaccination rates do not prevent pertussis transmission to at-risk infants and evolution of the pertussis virus may be responsible for more potent and dangerous strains.
PMID: Vaccine. 2010 Dec 10 ;29(1):11-6. Epub 2010 Oct 27. PMID: 21034823 Abstract Title: Imperfect vaccine-induced immunity and whooping cough transmission to infants. Abstract: Whooping cough, caused by B. pertussis and B. parapertussis, has increased in incidence throughout much of the developed world since the 1980s despite high vaccine coverage, causing an increased risk of …
This study provides additional evidence of waning immunity following Tdap vaccination.
PMID: J Infect Dis. 2014 Sep 15 ;210(6):942-53. Epub 2014 Jun 5. PMID: 24903664 Abstract Title: Estimating the effectiveness of tetanus-diphtheria-acellular pertussis vaccine (Tdap) for preventing pertussis: evidence of rapidly waning immunity and difference in effectiveness by Tdap brand. Abstract: BACKGROUND: We estimated the vaccine effectiveness (VE) of tetanus-diphtheria-acellular pertussis vaccine (Tdap) for preventing pertussis …
Tdap vaccination did not prevent pertussis outbreaks. DTaP protection against pertussis wanes rapidly.
PMID: Pediatrics. 2016 Mar ;137(3):e20153326. Epub 2016 Feb 5. PMID: 26908667 Abstract Title: Waning Tdap Effectiveness in Adolescents. Abstract: BACKGROUND AND OBJECTIVE: Because the effectiveness of diphtheria-tetanus-acellular pertussis (DTaP) vaccine wanes substantially after the fifth dose at ages 4 to 6 years, there is a growing cohort of adolescents who rely on tetanus toxoid, reduced …
Aqueous garlic extract supresses experimental gentamicin induced renal pathophysiology mediated by oxidative stress, inflammation and Kim-1.
PMID: Pathophysiology. 2019 Jul 29. Epub 2019 Jul 29. PMID: 31383388 Abstract Title: Aqueous garlic extract supresses experimental gentamicin induced renal pathophysiology mediated by oxidative stress, inflammation and Kim-1. Abstract: BACKGROUND: Gentamicin (Gent) has rapid&high bactericidal action in addition to its cheap price. Nevertheless, 30% of gentamicin-treated patients develop nephrotoxicity.OBJECTIVE: To explore the probable nephroprotective …
These results indicate that age-sensitive contact with commensal microbes is critical for establishing mucosal iNKT cell tolerance to later environmental exposures.
PMID: Science. 2012 Apr 27 ;336(6080):489-93. Epub 2012 Mar 22. PMID: 22442383 Abstract Title: Microbial exposure during early life has persistent effects on natural killer T cell function. Abstract: Exposure to microbes during early childhood is associated with protection from immune-mediated diseases such as inflammatory bowel disease (IBD) and asthma. Here, we show that in …
Mumps parotitis may lead to expression and immune recognition of a tumor-associated form of MUC1 and create effective immune surveillance of ovarian cancer cells that express this form of MUC1.
PMID: Cancer Causes Control. 2010 Aug ;21(8):1193-201. Epub 2010 Jun 18. PMID: 20559706 Abstract Title: Mumps and ovarian cancer: modern interpretation of an historic association. Abstract: BACKGROUND: Epidemiologic studies found childhood mumps might protect against ovarian cancer. To explain this association, we investigated whether mumps might engender immunity to ovarian cancer through antibodies against the …
Measles and mumps, especially in case of both infections, were associated with lower risks of mortality from atherosclerotic CVD.
PMID: Atherosclerosis. 2015 Aug ;241(2):682-6. Epub 2015 Jun 18. PMID: 26122188 Abstract Title: Association of measles and mumps with cardiovascular disease: The Japan Collaborative Cohort (JACC) study. Abstract: OBJECTIVE: Although it has been suggested that exposure to infections during childhood could decrease risk of atherosclerotic cardiovascular disease (CVD), the evidence is scarce. We investigated the association …
This study identified 130% more cases of measles among 2-dose measles vaccination recipients.
PMID: J Infect Dis. 2013 Mar 15 ;207(6):990-8. Epub 2012 Dec 21. PMID: 23264672 Abstract Title: Largest measles epidemic in North America in a decade–Quebec, Canada, 2011: contribution of susceptibility, serendipity, and superspreading events. Abstract: BACKGROUND: The largest measles epidemic in North America in the last decade, occurred in 2011 in Quebec, Canada, where rates …
As measles immunization rates rise to high levels in a population, measles becomes a disease of immunized persons.
PMID: Arch Intern Med. 1994 Aug 22 ;154(16):1815-20. PMID: 8053748 Abstract Title: Failure to reach the goal of measles elimination. Apparent paradox of measles infections in immunized persons. Abstract: BACKGROUND: Measles is the most transmissible disease known to man. During the 1980s, the number of measles cases in the United States rose dramatically. Surprisingly, 20% …