Oroxylin A induces apoptosis of activated hepatic stellate cells through endoplasmic reticulum stress.

PMID:  Apoptosis. 2019 Dec ;24(11-12):905-920. PMID: 31538267 Abstract Title:  Oroxylin A induces apoptosis of activated hepatic stellate cells through endoplasmic reticulum stress. Abstract:  Hepatic stellate cell (HSC) activation plays an indispensable role in hepatic fibrosis. Inducing apoptosis of activated HSCs can attenuate or reverse fibrogenesis. In this study, we initially found that oroxylin A (OA) …

Synergistic effect of 5-fluorouracil and the flavanoid oroxylin A on HepG2 human hepatocellular carcinoma.

PMID:  Cancer Chemother Pharmacol. 2010 Feb ;65(3):481-9. Epub 2009 Jul 8. PMID: 19585117 Abstract Title:  Synergistic effect of 5-fluorouracil and the flavanoid oroxylin A on HepG2 human hepatocellular carcinoma and on H22 transplanted mice. Abstract:  AIM: To investigate the synergistic inhibitory effects of the combination of 5-fluorouracil (5-FU) with the natural flavanoid oroxylin A on …

Superhongmi extract diet supplementation significantly suppressed hyperglycemia, oxidative stress, and bone resorption.

PMID:  Prev Nutr Food Sci. 2019 Jun ;24(2):144-149. Epub 2019 Jun 30. PMID: 31328118 Abstract Title:  Effects of 'Superhongmi' Rice Bran Extracts on Biochemical Markers of Glycolysis and Bone Metabolism in Ovariectomized Rats. Abstract:  Middle aged women naturally enter menopause, which increases the risk of several metabolic diseases. The objective of this research was to …

Arabinoxylan rice bran (Biobran) suppresses the viremia level in patients with chronic HCV infection.

PMID:  Int J Immunopathol Pharmacol. 2016 Dec ;29(4):647-653. Epub 2016 Oct 31. PMID: 27799299 Abstract Title:  Arabinoxylan rice bran (Biobran) suppresses the viremia level in patients with chronic HCV infection: A randomized trial. Abstract:  Current treatments for Hepatitis C virus (HCV) have severe side effects and are very expensive. There is a need to explore …

Biobran/MGN-3, an arabinoxylan rice bran, enhances NK cell activity in geriatric subjects.

PMID:  Exp Ther Med. 2018 Mar ;15(3):2313-2320. Epub 2018 Jan 8. PMID: 29456638 Abstract Title:  Biobran/MGN-3, an arabinoxylan rice bran, enhances NK cell activity in geriatric subjects: A randomized, double-blind, placebo-controlled clinical trial. Abstract:  Aging is associated with a decline in natural killer (NK) and natural killer T (NKT) cell function that may contribute to …

Rice bran extract supplement improves sleep efficiency and sleep onset in adults with sleep disturbance.

PMID:  Sci Rep. 2019 Aug 26 ;9(1):12339. Epub 2019 Aug 26. PMID: 31451704 Abstract Title:  Rice bran extract supplement improves sleep efficiency and sleep onset in adults with sleep disturbance: A randomized, double-blind, placebo-controlled, polysomnographic study. Abstract:  We previously reported that rice bran extract supplement (RBS) administration to mice decreased sleep latency and induced non-rapid …

Rice bran reduces weight gain and modulates lipid metabolism in rats with high-energy-diet-induced obesity.

PMID:  Nutrients. 2019 Aug 30 ;11(9). Epub 2019 Aug 30. PMID: 31480353 Abstract Title:  Rice Bran Reduces Weight Gain and Modulates Lipid Metabolism in Rats with High-Energy-Diet-Induced Obesity. Abstract:  Obesity has become an epidemic worldwide. It is a complex metabolic disorder associated with many serious complications and high morbidity. Rice bran is a nutrient-dense by …

Arabinoxylan rice bran (MGN-3/Biobran) enhances radiotherapy in animals bearing Ehrlich ascites carcinoma.

PMID:  J Radiat Res. 2019 Aug 29. Epub 2019 Aug 29. PMID: 31504707 Abstract Title:  Arabinoxylan rice bran (MGN-3/Biobran) enhances radiotherapy in animals bearing Ehrlich ascites carcinoma†. Abstract:  This study examines the ability of arabinoxylan rice bran (MGN-3/Biobran) to enhance the anti-cancer effects of fractionated X-ray irradiation of Ehrlich solid tumor-bearing mice. Swiss albino mice …

Habitual mushroom intake might help to prevent prostate cancer.

PMID:  Int J Cancer. 2019 Sep 4. Epub 2019 Sep 4. PMID: 31486077 Abstract Title:  Mushroom consumption and incident risk of prostate cancer in Japan: A pooled analysis of the Miyagi Cohort Study and the Ohsaki Cohort Study. Abstract:  In vivo and in vitro evidence has shown that mushrooms have the potential to prevent prostate …

Virgin rice bran oil alleviates hypertension.

PMID:  Nutrition. 2019 Aug 26 ;69:110575. Epub 2019 Aug 26. PMID: 31585258 Abstract Title:  Virgin rice bran oil alleviates hypertension through the upregulation of eNOS and reduction of oxidative stress and inflammation in L-NAME-induced hypertensive rats. Abstract:  OBJECTIVE: Endothelial dysfunction associated with reduction in nitric oxide (NO) bioavailability plays an important role in development of …

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