Category Archives: Uncategorized

PMID:  Environ Health Perspect. 2019 01 ;127(1):17005. PMID: 30648881 Abstract Title:  High Pesticide Exposure Events and Olfactory Impairment among U.S. Farmers. Abstract:  BACKGROUND: Olfactory impairment (OI) is common among older adults and independently predicts all-cause mortality and the risk of several major neurodegenerative diseases. Pesticide exposure may impair olfaction, but empirical evidence is lacking.OBJECTIVE: We …

Continue reading “High pesticide exposure events may cause long-lasting olfactory deficit.”

PMID:  Environ Int. 2019 04 ;125:161-171. Epub 2019 Feb 1. PMID: 30716576 Abstract Title:  Plasma levels of dichlorodiphenyldichloroethene (DDE) and dichlorodiphenyltrichloroethane (DDT) and survival following breast cancer in the Carolina Breast Cancer Study. Abstract:  OBJECTIVES: To examine plasma levels of dichlorodiphenyldichloroethene (DDE) and dichlorodiphenyltrichloroethane (DDT) in association with survival among women with breast cancer who …

Continue reading “Exposure to DDE/DDT may adversely impact overall and breast cancer-specific survival.”

n/a PMID:  J Natl Cancer Inst. 2019 Feb 13. Epub 2019 Feb 13. PMID: 30759253 Abstract Title:  DDT and Breast Cancer: Prospective Study of Induction Time and Susceptibility Windows. Abstract:  Background: In a previous Child Health and Development Studies report, p, p'-DDT was associated with a fivefold increased risk of premenopausal (before age 50 years) …

Continue reading “DDT was associated with breast cancer through age 54 years.”

PMID:  Reprod Toxicol. 2019 Feb 26. Epub 2019 Feb 26. PMID: 30822522 Abstract Title:  DDT exposure during pregnancy and DNA methylation alterations in female offspring in the Child Health and Development Study. Abstract:  Studies measuring dichlorodiphenyltrichloroethane (DDT) exposure during key windows of susceptibility including the intrauterine period suggest that DDT exposure is associated with breast …

Continue reading “These findings suggest prenatal DDT exposure may have life-long consequence through alteration in genes relevant to breast cancer.”

PMID:  J Cell Biochem. 2019 Sep ;120(9):14847-14859. Epub 2019 Apr 22. PMID: 31009110 Abstract Title:  Organochlorine and organophosphorus pesticides and bladder cancer: A case-control study. Abstract:  BACKGROUND: Exposure to pesticides is associated with an increase in the incidence of cancer. We aimed to investigate the association of serum organochlorine pesticides (OCPs) and organophosphorus pesticides (OPs) …

Continue reading “Organochlorine and organophosphorus pesticides and bladder cancer.”

PMID:  Environ Epigenet. 2019 Apr ;5(2):dvz008. Epub 2019 May 27. PMID: 31186947 Abstract Title:  Sperm epimutation biomarkers of obesity and pathologies following DDT induced epigenetic transgenerational inheritance of disease. Abstract:  Dichlorodiphenyltrichloroethane (DDT) has previously been shown to promote the epigenetic transgenerational inheritance of adult onset disease in rats. The current study investigated the potential that …

Continue reading “Sperm epimutation biomarkers of obesity and pathologies following DDT induced epigenetic transgenerational inheritance of disease.”

PMID:  Environ Toxicol Pharmacol. 2019 Nov ;72:103263. Epub 2019 Sep 12. PMID: 31542660 Abstract Title:  The organochlorine pesticides pentachlorophenol and dichlorodiphenyltrichloroethane increase secretion and production of interleukin 6 by human immune cells. Abstract:  The environmental contaminants pentachlorophenol (PCP) and 4, 4'-dichlorodiphenyltrichloroethane (DDT) are detected in some human blood samples at levels as high as 5μM …

Continue reading “Both pentachlorophenol and DDT have the potential to produce chronic inflammation.”

PMID:  Int J Hyg Environ Health. 2019 Nov 8. Epub 2019 Nov 8. PMID: 31708466 Abstract Title:  Multiple pesticides in mothers' hair samples and children's measurements at birth: Results from the French national birth cohort (ELFE). Abstract:  BACKGROUND: A growing body of studies now suggests that the general population is continuously and ubiquitously exposed to …

Continue reading “These results suggest that prenatal exposure to 19 pesticides or metabolites from various chemical families may influence measurements at birth.”

PMID:  Reprod Toxicol. 2019 Nov 8. Epub 2019 Nov 8. PMID: 31711904 Abstract Title:  In Utero DDT Exposure and Breast Density Before Age 50. Abstract:  Prior studies in the Child Health and Development Studies (CHDS) found in utero exposure to the pesticide, dichlorodiphenyltrichloroethane (DDT), increased breast cancer risk by age 52. Mammographic density is considered …

Continue reading “In utero DDT exposure and breast density before age 50.”

PMID:  World J Gastroenterol. 2007 Jan 14 ;13(2):250-6. PMID: 17226904 Abstract Title:  Antiproliferation and apoptosis induction of paeonol in HepG2 cells. Abstract:  AIM: To investigate the antiproliferative effect of paeonol (Pae) used alone or in combination with chemotherapeutic agents [cisplatin (CDDP), doxorubicin (DOX) and 5-fluorouracil (5-FU)] on human hepatoma cell line HepG2 and the possible …

Continue reading “Antiproliferation and apoptosis induction of paeonol in HepG2 cells.”