Nonthermal induction of heat shock protein 70 and heterogeneous nuclear ribonucleoprotein K are involved in the stress reaction of human lens epithelial cells to electromagnetic fields.

PMID:  Jpn J Ophthalmol. 2007 Nov-Dec;51(6):412-6. Epub 2007 Dec 21. PMID: 18158590 Abstract Title:  Proteomic analysis of human lens epithelial cells exposed to microwaves. Abstract:  PURPOSE: To study proteomic changes in human lens epithelial cells (HLECs) exposed to 1800-MHz Global System for Mobile Communication (GSM)-like microwaves.METHODS: In three separate experiments, HLECs were exposed and sham-exposed …

Activation of heat shock protein 27 pathway may be a mechanism that underpins the electromagnetic field-cancer connection.

PMID:  Differentiation. 2002 May ;70(2-3):120-9. PMID: 12076339 Abstract Title:  Non-thermal activation of the hsp27/p38MAPK stress pathway by mobile phone radiation in human endothelial cells: molecular mechanism for cancer- and blood-brain barrier-related effects. Abstract:  We have examined whether non-thermal exposures of cultures of the human endothelial cell line EA.hy926 to 900 MHz GSM mobile phone microwave …

Radiofrequency fields at 2.45 GHz can alter gene expression in human cells by a non-thermal mechanism.

PMID:  Mutat Res. 2013 Jan 20 ;750(1-2):27-33. Epub 2012 Oct 8. PMID: 23059817 Abstract Title:  Comparison of cytotoxic and genotoxic effects of plutonium-239 alpha particles and mobile phone GSM 900 radiation in the Allium cepa test. Abstract:  The goal of this study was to compare the cytotoxic and genotoxic effects of plutonium-239 alpha particles and …

Probiotic kefir was able to attenuate the molecular, structural, and physiological cardiovascular changes induced by BPA.

PMID:  J Nutr Biochem. 2019 Oct 25 ;75:108254. Epub 2019 Oct 25. PMID: 31707283 Abstract Title:  Bisphenol A contamination in infant rats: molecular, structural, and physiological cardiovascular changes and the protective role of kefir. Abstract:  The effects of bisphenol A (BPA) contamination on the cardiovascular function still are not clear. Here, we evaluated the vascular …

Paeonol has significantly growth-inhibitory and apoptosis-inducing effects in gastric cancer cells both in vitro and in vivo.

PMID:  World J Gastroenterol. 2010 Sep 21 ;16(35):4483-90. PMID: 20845518 Abstract Title:  Paeonol inhibits tumor growth in gastric cancer in vitro and in vivo. Abstract:  AIM: To investigate the anti-tumor effects of paeonol in gastric cancer cell proliferation and apoptosis in vitro and in vivo.METHODS: Murine gastric cancer cell line mouse forestomach carcinoma (MFC) or …

Paeonol attenuates airway inflammation and hyperresponsiveness in a murine model of ovalbumin-induced asthma.

PMID:  Can J Physiol Pharmacol. 2010 Oct ;88(10):1010-6. PMID: 20962901 Abstract Title:  Paeonol attenuates airway inflammation and hyperresponsiveness in a murine model of ovalbumin-induced asthma. Abstract:  Paeonol, the main active component isolated from Moutan Cortex, possesses extensive pharmacological activities such as anti-inflammatory, anti-allergic, and immunoregulatory effects. In the present study, we examined the effects of …

Paeonol attenuates hydrogen peroxide-induced NF-κB-associated amyloid precursor protein expression.

PMID:  Am J Chin Med. 2010 ;38(6):1171-92. PMID: 21061469 Abstract Title:  Paeonol attenuates H₂O₂-induced NF-κB-associated amyloid precursor protein expression. Abstract:  Hydrogen peroxide (H₂O₂) has been shown to promote neurodegeneration by inducing the activation of nuclear factor-κB (NF-κB). In this study, NF-κB activation was induced by H₂O₂ in human neuroblastoma SH-SY5Y cells. Whether paeonol, one of …

Paeonol increases levels of cortical cytochrome oxidase and vascular actin and improves behavior in a rat model of Alzheimer’s disease.

PMID:  Brain Res. 2011 May 4 ;1388:141-7. Epub 2011 Mar 4. PMID: 21377451 Abstract Title:  Paeonol increases levels of cortical cytochrome oxidase and vascular actin and improves behavior in a rat model of Alzheimer's disease. Abstract:  Paeonol(2'-hydroxy-4'-methoxyacetophenone;1-(2-hydroxy-4-methoxyphenyl)ethan-1-one) is a constituent of the bark of the Moutan Cortex (Paeonia suffruticosa). This bark has been used as …

Paeonol protects memory after ischemic stroke via inhibiting β-secretase and apoptosis.

PMID:  Evid Based Complement Alternat Med. 2012 ;2012:932823. Epub 2012 Mar 13. PMID: 22474531 Abstract Title:  Paeonol Protects Memory after Ischemic Stroke via Inhibitingβ-Secretase and Apoptosis. Abstract:  Poststroke dementia commonly occurs following stroke, with its pathogenesis related toβ-amyloid production and apoptosis. The present study evaluate the effects of paeonol, one of the phenolic phytochemicals isolated …

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