PMID: Obesity (Silver Spring). 2019 Apr ;27(4):542-550. Epub 2019 Feb 14. PMID: 30767409 Abstract Title: Attenuation of Postmeal Metabolic Indices with Red Raspberries in Individuals at Risk for Diabetes: A Randomized Controlled Trial. Abstract: OBJECTIVE: This study investigated the effect of red raspberry intake on meal-induced postprandial metabolic responses in individuals who have overweight or …
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Flavan-3-ols content in red raspberry leaves increases under blue led-light irradiation.
PMID: Metabolites. 2019 Mar 21 ;9(3). Epub 2019 Mar 21. PMID: 30901937 Abstract Title: Flavan-3-ols Content in Red Raspberry Leaves Increases under Blue Led-Light Irradiation. Abstract: Berry fruits are well known to contain large amounts of polyphenol compounds. Among them, flavan-3-ol derivatives are a group of secondary metabolism compounds currently attracting a great deal of …
Chlorogenic acid prevents paraquat-induced apoptosis via Sirt1-mediated regulation of redox and mitochondrial function.
PMID: Free Radic Res. 2019 Jun ;53(6):680-693. Epub 2019 Jun 4. PMID: 31106605 Abstract Title: Chlorogenic acid prevents paraquat-induced apoptosis via Sirt1-mediated regulation of redox and mitochondrial function. Abstract: Paraquat (PQ) is a widely used agro-chemical in agriculture and highly toxic to humans. Although the mechanism of PQ poisoning is not clear, it has been …
Chlorogenic acid attenuates dextran sodium sulfate-induced ulcerative colitis.
PMID: Biomed Res Int. 2019 ;2019:6769789. Epub 2019 Apr 18. PMID: 31139644 Abstract Title: Chlorogenic Acid Attenuates Dextran Sodium Sulfate-Induced Ulcerative Colitis in Mice through MAPK/ERK/JNK Pathway. Abstract: Objective: Observe the protective effect of chlorogenic acid on dextran sulfate-induced ulcerative colitis in mice and explore the regulation of MAPK/ERK/JNK signaling pathway.Methods: Seventy C57BL/6 mice (half …
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Neuroprotective effect of chlorogenic acid in global cerebral ischemia-reperfusion rat model.
PMID: Naunyn Schmiedebergs Arch Pharmacol. 2019 Oct ;392(10):1293-1309. Epub 2019 Jun 12. PMID: 31190087 Abstract Title: Neuroprotective effect of chlorogenic acid in global cerebral ischemia-reperfusion rat model. Abstract: The ischemic cascade is initiated in the hypoperfused region of the brain that leads to neuronal cell death. Identification of multi-target inhibitor against prominent molecular mediators of …
Chlorogenic acid attenuates cadmium-induced intestinal injury in Sprague-Dawley rats.
PMID: Food Chem Toxicol. 2019 Nov ;133:110751. Epub 2019 Aug 4. PMID: 31390532 Abstract Title: Chlorogenic acid attenuates cadmium-induced intestinal injury in Sprague-Dawley rats. Abstract: Chronic exposure to cadmium (Cd) causes remarkable damage to the liver and gastrointestinal tract. Previous studies have revealed that chlorogenic acid (CGA) could improve the intestinal barrier integrity for weaned …
Obesogen effect of bisphenol S alters mRNA expression and DNA methylation profiling in male mouse liver.
PMID: Chemosphere. 2019 Oct 15 ;241:125092. Epub 2019 Oct 15. PMID: 31683443 Abstract Title: Obesogen effect of bisphenol S alters mRNA expression and DNA methylation profiling in male mouse liver. Abstract: Environmental pollution is increasingly considered an important factor involved in the obesity incidence. Endocrine disruptors (EDs) are important actors in the concept of DOHaD …
Bisphenol S rapidly depresses heart function through estrogen receptor-β and decreases phospholamban phosphorylation in a sex-dependent manner.
PMID: Sci Rep. 2019 Nov 4 ;9(1):15948. Epub 2019 Nov 4. PMID: 31685870 Abstract Title: Bisphenol S rapidly depresses heart function through estrogen receptor-β and decreases phospholamban phosphorylation in a sex-dependent manner. Abstract: The health effects of the endocrine disruptor Bisphenol A (BPA) led to its partial replacement with Bisphenol S (BPS) in several products …
BPS and BPA are environmental pollutants that may affect mammary development and may contribute to the development of breast cancer.
PMID: Sci Rep. 2019 Nov 5 ;9(1):16005. Epub 2019 Nov 5. PMID: 31690802 Abstract Title: Bisphenol S and Bisphenol A disrupt morphogenesis of MCF-12A human mammary epithelial cells. Abstract: Breast cancer is one of the most common cancers diagnosed in women worldwide. Genetic predisposition, such as breast cancer 1 (BRCA1) mutations, account for a minor …
Chlorogenic acid ameliorates memory loss and hippocampal cell death after transient global ischemia.
PMID: Eur J Neurosci. 2019 Aug 22. Epub 2019 Aug 22. PMID: 31437868 Abstract Title: Chlorogenic acid ameliorates memory loss and hippocampal cell death after transient global ischemia. Abstract: Chlorogenic acid (CGA) is known to have antioxidant potentials, yet the effect of CGA on brain ischemia has not been sufficiently understood. Brain ischemia such as …