PMID: J Cell Physiol. 2019 Oct 10. Epub 2019 Oct 10. PMID: 31602671 Abstract Title: Chlorogenic acid activates ERK1/2 and inhibits proliferation of osteosarcoma cells. Abstract: Osteosarcoma (OS) is a very aggressive metastatic pediatric and adolescent tumor. Due to its recurrent development of chemotherapy resistance, clinical outcome for OS patients remains poor. Therefore, discovering more …
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CGA has been shown to reduce inflammation and modulate inflammatory and neuropathic pain in animal models.
PMID: Curr Neuropharmacol. 2019 Oct 21. Epub 2019 Oct 21. PMID: 31631820 Abstract Title: Pharmacologic overview of chlorogenic acid and its metabolites in chronic pain and inflammation. Abstract: BACKGROUND: Natural phenolic compounds in medicinal herbs and dietary plants are antioxidants which play therapeutic or preventive roles in different pathological situations, such as oxidative stress and …
Chlorogenic acid attenuates kidney ischemic/reperfusion injury.
PMID: Biomed Res Int. 2019 ;2019:5423703. Epub 2019 Sep 22. PMID: 31662982 Abstract Title: Chlorogenic Acid Attenuates Kidney Ischemic/Reperfusion Injury via Reducing Inflammation, Tubular Injury, and Myofibroblast Formation. Abstract: Kidney ischemic/reperfusion (I/R) injury is the main cause of acute kidney injury (AKI) involving renal function deterioration, renal architecture damage, and inflammation. This condition may lead …
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Effects of rosmarinic acid on immunoregulatory activity and hepatocellular carcinoma cell apoptosis in H22 tumor-bearing mice.
PMID: Korean J Physiol Pharmacol. 2019 Nov ;23(6):501-508. Epub 2019 Oct 24. PMID: 31680772 Abstract Title: Effects of rosmarinic acid on immunoregulatory activity and hepatocellular carcinoma cell apoptosis intumor-bearing mice. Abstract: Rosmarinic acid (RA) is a natural polyphenolic compound that exists in many medicinal species ofand. The previous studies have revealed that RA had therapeutic …
Iron fortification and bioavailability of chickpea seeds and flour.
PMID: Nutrients. 2019 Sep 18 ;11(9). Epub 2019 Sep 18. PMID: 31540391 Abstract Title: Iron Fortification and Bioavailability of Chickpea (L.) Seeds and Flour. Abstract: Iron (Fe) deficiency is one of the most common nutritional disorders, and is mainly due to insufficient intake of bioavailable Fe. Chickpea (L.) was examined as a potential vehicle for …
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Flavonoids extracted from mulberry leaf improve skeletal muscle mitochondrial function by activating AMPK in type 2 diabetes.
PMID: J Ethnopharmacol. 2019 Oct 19:112326. Epub 2019 Oct 19. PMID: 31639486 Abstract Title: Flavonoids extracted from mulberry (Morus alba L.) leaf improve skeletal muscle mitochondrial function by activating AMPK in type 2 diabetes. Abstract: ETHNOPHARMACOLOGICAL RELEVANCE: Mulberry (Morus alba L.) leaves have been widely applied to controlling blood glucose as an efficacious traditional Chinese …
Therapeutic potential of Artemisia vulgaris: An insight into underlying immunological mechanisms.
PMID: J Environ Pathol Toxicol Oncol. 2019 ;38(3):205-216. PMID: 31679308 Abstract Title: Therapeutic potential of Artemisia vulgaris: An insight into underlying immunological mechanisms. Abstract: Artemisia vulgaris is a traditional Chinese herb believed to have a wide range of healing properties; it is traditionally used to treat numerous health ailments. The plant is commonly called mugwort …
Continuous intake of chlorogenic acids appears to improve attention and executive function among cognitive functions in mild cognitive impairment.
PMID: J Alzheimers Dis. 2019 Oct 29. Epub 2019 Oct 29. PMID: 31683483 Abstract Title: Effect of Chlorogenic Acids on Cognitive Function in Mild Cognitive Impairment: A Randomized Controlled Crossover Trial. Abstract: BACKGROUND: Mild cognitive impairment (MCI) is a global-scale issue, due in large part to the rapidly growing elderly population. The main polyphenol contained …
Red raspberry extract intake ameliorates hyperlipidemia.
PMID: Food Chem Toxicol. 2019 Nov ;133:110796. Epub 2019 Aug 28. PMID: 31472226 Abstract Title: Red raspberry extract (Rubus idaeus L shrub) intake ameliorates hyperlipidemia in HFD-induced mice through PPAR signaling pathway. Abstract: Effects of red raspberry extract (RRE) intake on hyperlipidemia mice induced by high-fat diet (HFD) were investigated in this study. After intragastric …
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Fermented blackberry by Lactobacillus plantarum can be a potential candidate for protecting skin aging against UV irradiation.
PMID: Nutrients. 2019 Oct 11 ;11(10). Epub 2019 Oct 11. PMID: 31614689 Abstract Title: Fermentation of Blackberry withJBMI F5 Enhance the Protection Effect on UVB-Mediated Photoaging in Human Foreskin Fibroblast and Hairless Mice through Regulation of MAPK/NF-κB Signaling. Abstract: Chronic and extensive exposure of ultraviolet (UV)-irradiation causes human skin sunburn, inflammation, or photoaging, which is …
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