PMID: ACS Chem Neurosci. 2019 Nov 7. Epub 2019 Nov 7. PMID: 31697467 Abstract Title: The natural flavonoid Naringenin elicits analgesia through inhibition of NaV1.8 voltage-gated sodium channels. Abstract: Naringenin (2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one is a natural flavonoid found in fruits from the citrus family. Since (2S)-Naringenin is known to racemize, its bioactivity might be related to one …
Category Archives: Uncategorized
Clinical pharmacology of Citrus aurantium and Citrus sinensis for the treatment of anxiety.
PMID: Evid Based Complement Alternat Med. 2018 ;2018:3624094. Epub 2018 Dec 2. PMID: 30622597 Abstract Title: Clinical Pharmacology ofandfor the Treatment of Anxiety. Abstract: Objective: The aim of this review is to analyze preclinical and clinical studies investigating the anxiety effects oforessential oils (EOs).Design: The bibliographic research was made on the major scientific databases. Analysis …
Fermented wheat germ extract inhibits glycolysis/pentose cycle enzymes and induces apoptosis in Jurkat T-cell leukemia tumor cells.
PMID: J Biol Chem. 2002 Nov 29 ;277(48):46408-14. Epub 2002 Sep 25. PMID: 12351627 Abstract Title: Fermented wheat germ extract inhibits glycolysis/pentose cycle enzymes and induces apoptosis through poly(ADP-ribose) polymerase activation in Jurkat T-cell leukemia tumor cells. Abstract: The fermented extract of wheat germ, trade name Avemar, is a complex mixture of biologically active molecules …
Fermented wheat germ extract (avemar) inhibits adjuvant arthritis.
PMID: Ann N Y Acad Sci. 2007 Sep ;1110:348-61. PMID: 17911450 Abstract Title: Fermented wheat germ extract (avemar) inhibits adjuvant arthritis. Abstract: Anti-inflammatory efficacy of the fermented wheat germ extract (FWGE, Avemar) in the rat adjuvant arthritis (AA) model was examined. To Wistar rats with AA, different doses of FWGE and anti-inflammatory drugs (indomethacin, dexamethasone) …
Continue reading “Fermented wheat germ extract (avemar) inhibits adjuvant arthritis.”
Avemar (wheat germ extract) in cancer prevention and treatment.
PMID: Nutr Cancer. 2009 ;61(6):891-9. PMID: 20155632 Abstract Title: Avemar (wheat germ extract) in cancer prevention and treatment. Abstract: Many healthy foods are derived from wheat germ. The molecular composition of these products, however, greatly differs as shown by normal-phase HPLC-mass spectrometry analysis; thus, experimental data obtained by one of them is not necessarily true …
Continue reading “Avemar (wheat germ extract) in cancer prevention and treatment.”
Promising cytotoxic activity profile of fermented wheat germ extract in human cancer cell lines.
PMID: J Exp Clin Cancer Res. 2011 Apr 16 ;30:42. Epub 2011 Apr 16. PMID: 21496306 Abstract Title: Promising cytotoxic activity profile of fermented wheat germ extract (Avemar®) in human cancer cell lines. Abstract: Fermented wheat germ extract (FWGE) is currently used as nutrition supplement for cancer patients. Limited recent data suggest antiproliferative, antimetastatic and …
Wheat germ extract inhibits experimental colon carcinogenesis.
PMID: Carcinogenesis. 2001 Oct ;22(10):1649-52. PMID: 11577004 Abstract Title: Wheat germ extract inhibits experimental colon carcinogenesis in F-344 rats. Abstract: It has been demonstrated for the first time that a wheat germ extract prevents colonic cancer in laboratory animals. Four-week-old inbred male F-344 rats were used in the study. Colon carcinogenesis has been induced by …
Continue reading “Wheat germ extract inhibits experimental colon carcinogenesis.”
Wheat germ extract decreases glucose uptake and RNA ribose formation but increases fatty acid synthesis in MIA pancreatic adenocarcinoma cells.
PMID: Pancreas. 2001 Aug ;23(2):141-7. PMID: 11484916 Abstract Title: Wheat germ extract decreases glucose uptake and RNA ribose formation but increases fatty acid synthesis in MIA pancreatic adenocarcinoma cells. Abstract: The fermented wheat germ extract with standardized benzoquinone composition has potent tumor propagation inhibitory properties. The authors show that this extract induces profound metabolic changes …
The results suggested that the effect of flavonoids on inducing peroxidase might be one of the chemical prevention mechanisms on mammary tumors.
PMID: Wei Sheng Yan Jiu. 2001 Jul ;30(4):215-7. PMID: 12561518 Abstract Title: [Antioxidation of flavones of wheat germ on mammary tumor of rats]. Abstract: The effect of flavonoids of wheat germ on mammary tumor of rats induced by 7,12-dimethylben(a) anthracene (DMBA) was investigated. Sprague-Dawley female rats (50 day-old, weighted around 176 g) were randomly divided …
Effect of fermented wheat germ extract with lactobacillus plantarum dy-1 on HT-29 cell proliferation and apoptosis.
PMID: J Agric Food Chem. 2015 Mar 11 ;63(9):2449-57. Epub 2015 Mar 2. PMID: 25658135 Abstract Title: Effect of fermented wheat germ extract with lactobacillus plantarum dy-1 on HT-29 cell proliferation and apoptosis. Abstract: This study aimed to evaluate the anticarcinogenic activities of aqueous extract of fermented wheat germ with Lactobacillus plantarum dy-1 (LFWGE). The …
Health Time 