Vitamin E protects the reproductive system against diabetes mellitus.

PMID:  Int J Reprod Biomed (Yazd). 2019 Feb ;17(2). Epub 2019 Mar 19. PMID: 31435589 Abstract Title:  Protective effect of vitamin E on oxidative stress and sperm apoptosis in diabetic Mice. Abstract:  Background: Generation of free radicals and oxidative stress are a major contributor to diabetes. These factors lead to the development of diabetic testicles …

Protective role of vitamin E against cadmium induced oxidative stress into the rat liver.

PMID:  Tunis Med. 2019 Jan ;97(1):100-105. PMID: 31535700 Abstract Title:  Protective role of vitamin E against cadmium induced oxidative stress into the rat liver. Abstract:  INTRODUCTION: Cadmium (Cd) is a toxic heavy metal used in various industrial applications and therefore can cause, both by environmental or professional exposure, several damage in all body systems. The …

Vitamin E attenuates alterations in learning, memory and BDNF levels caused by perinatal ethanol exposure.

PMID:  Nutr Neurosci. 2019 Oct 14:1-15. Epub 2019 Oct 14. PMID: 31607237 Abstract Title:  Vitamin E attenuates alterations in learning, memory and BDNF levels caused by perinatal ethanol exposure. Abstract:  Alcohol exposure during pregnancy affects the developing fetus and causes a variety of physical and neurological abnormalities. Here we aim to study the effects of …

Neuroprotective and anti-obesity effects of tocotrienols.

PMID:  J Nutr Sci Vitaminol (Tokyo). 2019 ;65(Supplement):S185-S187. PMID: 31619626 Abstract Title:  Neuroprotective and Anti-Obesity Effects of Tocotrienols. Abstract:  Vitamin E is a natural lipophilic vitamin, and the most famous function of vitamin E is an antioxidant activity. Because we haveα-tocopherol transfer protein, many vitamin E-related reports are about α-tocopherol. Recently, other vitamin E isoforms, …

Morphine may be harmful in patients with angiogenesis-dependent cancers.

PMID:  Clin Exp Pharmacol Physiol. 2019 Oct 15. Epub 2019 Oct 15. PMID: 31612523 Abstract Title:  Morphine stimulates angiogenesis through Akt/mTOR/eIF4E activation under serum deprivation or HO-induced oxidative stress condition. Abstract:  Morphine is an opioid analgesic drug routinely used to treat pain in several medical conditions including cancer. Increasing evidence has shown that morphine can …

Morphine activates blast-phase chronic myeloid leukemia cells and alleviates the effects of tyrosine kinase inhibitors.

PMID:  Biochem Biophys Res Commun. 2019 Dec 10 ;520(3):560-565. Epub 2019 Oct 12. PMID: 31615652 Abstract Title:  Morphine activates blast-phase chronic myeloid leukemia cells and alleviates the effects of tyrosine kinase inhibitors. Abstract:  Morphine is an opioid analgesic drug routinely used in the postoperative period for pain management in cancer patients. In this work, we …

Exposure of NK cells to morphine decreased their ability to induce apoptosis in K562 cells.

PMID:  Brain Behav Immun. 2019 Oct 15. Epub 2019 Oct 15. PMID: 31626971 Abstract Title:  Morphine decreases the function of primary human natural killer cells by both TLR4 and opioid receptor signaling. Abstract:  BACKGROUND: Opioids are commonly used to provide analgesia for cancer pain, and functional opioid receptors have been identified on natural killer (NK) …

Monosodium glutamate supplementation can accelerate Alzheimer’s disease-like pathophysiology.

PMID:  J Alzheimers Dis. 2019 Oct 21. Epub 2019 Oct 21. PMID: 31658055 Abstract Title:  Oral Monosodium Glutamate Administration Causes Early Onset of Alzheimer's Disease-Like Pathophysiology in APP/PS1 Mice. Abstract:  Glutamate excitotoxicity has long been related to Alzheimer's disease (AD) pathophysiology, and it has been shown to affect the major AD-related hallmarks, amyloid-β peptide (Aβ) …

Testicular protective effects of ellagic acid on monosodium glutamate-induced testicular structural alterations.

PMID:  Ultrastruct Pathol. 2019 Oct 28:1-14. Epub 2019 Oct 28. PMID: 31658851 Abstract Title:  Testicular protective effects of ellagic acid on monosodium glutamate-induced testicular structural alterations in male rats. Abstract:  Ellagic acid (EA) has significant protective and antioxidant effects on several tissues. Monosodium glutamate (MG) is known as a flavor promoter that reversibly influences the …

CoQ10 ameliorates monosodium glutamate-induced alteration in detrusor activity and responsiveness in rats.

PMID:  BMC Urol. 2019 Oct 28 ;19(1):103. Epub 2019 Oct 28. PMID: 31660941 Abstract Title:  CoQ10 ameliorates monosodium glutamate-induced alteration in detrusor activity and responsiveness in rats via anti-inflammatory, anti-oxidant and channel inhibiting mechanisms. Abstract:  BACKGROUND: Competent detrusor muscles with coordinated contraction and relaxation are crucial for normal urinary bladder storage and emptying functions. Hence, …

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