Neurogenic factors may play a role in the disease process of acne.

PMID:  Eur J Dermatol. 2002 Sep-Oct;12(5):422-7. PMID: 12370127 Abstract Title:  Neuropeptides and sebaceous glands. Abstract:  This review provides a new insight into the participation of neuropeptides, notably substance P (SP), in the pathophysiology of acne. We show morphological alterations of sebaceous glands elicited by SP and differences in expression of various neurogenic factors in association …

Increased sebum levels do not directly cause development of acne lesions.

PMID:  Br J Dermatol. 2005 Nov ;153(5):919-24. PMID: 16225600 Abstract Title:  Does facial sebum excretion really affect the development of acne? Abstract:  BACKGROUND: It is generally accepted that the severity of acne is correlated with facial sebum secretion. However, previous studies on the relation between seborrhoea and the development of acne did not consider topographical …

Lipid peroxidation may precede acne formation and prime an increased susceptibility to co-morbid depression and anxiety in those with acne.

PMID:  Lipids Health Dis. 2010 Dec 9 ;9:141. Epub 2010 Dec 9. PMID: 21143923 Abstract Title:  Clinical implications of lipid peroxidation in acne vulgaris: old wine in new bottles. Abstract:  Acne vulgaris is a common dermatological disorder, one that is frequently associated with depression, anxiety and other psychological sequelae. In recent years there has been …

Pantothenate deficiency could lead to neurodegeneration/dementia in Huntington’s disease that might be preventable by treatment with vitamin B5.

PMID:  Metabolites. 2019 Jun 11 ;9(6). Epub 2019 Jun 11. PMID: 31212603 Abstract Title:  Cerebral Vitamin B5 (D-Pantothenic Acid) Deficiency as a Potential Cause of Metabolic Perturbation and Neurodegeneration in Huntington's Disease. Abstract:  Huntington's disease (HD) is a neurodegenerative disorder caused by an expanded CAG repeat in exon 1 of thegene. HD usually manifests in …

These result shows that pantothenic acid rich diet can protect bone loss from estrogen deficiency.

PMID:  Am J Transl Res. 2019 ;11(8):5008-5018. Epub 2019 Aug 15. PMID: 31497217 Abstract Title:  Vitamin B5 inhibit RANKL induced osteoclastogenesis and ovariectomy induced osteoporosis by scavenging ROS generation. Abstract:  B vitamins are a class of water-soluble vitamins that play important roles in cell metabolism. The participation of B vitamins in bone health has been …

Gestational B-vitamin supplementation alleviates PM2.5-induced autism-like behavior and hippocampal neurodevelopmental impairment in mice offspring.

PMID:  Ecotoxicol Environ Saf. 2019 Dec 15 ;185:109686. Epub 2019 Sep 20. PMID: 31546205 Abstract Title:  Gestational B-vitamin supplementation alleviates PM-induced autism-like behavior and hippocampal neurodevelopmental impairment in mice offspring. Abstract:  Gestational exposure to PMis a worldwide environmental issue associated with long-lasting behavior abnormalities and neurodevelopmental impairments in the hippocampus of offspring. PMmay induce hippocampus …

Vitamin D supplementation could ameliorate AGEs–RAGE signaling pathway in T2DM patients.

PMID:  Diabetol Metab Syndr. 2019 ;11:86. Epub 2019 Oct 26. PMID: 31673295 Abstract Title:  Effects of vitamin D supplementation on advanced glycation end products signaling pathway in T2DM patients: a randomized, placebo-controlled, double blind clinical trial. Abstract:  Background: Several researches have recommended vitamin D possible health benefits on diabetic complications development, but a few number …

Vitamin D deficiency is significantly associated with risk of proliferative diabetic retinopathy.

PMID:  Horm Metab Res. 2019 Nov ;51(11):729-734. Epub 2019 Nov 4. PMID: 31683343 Abstract Title:  Could Vitamin D be Associated with Proliferative Diabetic Retinopathy? Evidence from Pooling Studies. Abstract:  Contrasting data about the association between proliferative diabetic retinopathy (PDR) and vitamin D status remain unknown. First, a hospital-based cross-sectional study consisting of 889 diabetic retinopathy …

Blueberry supplementation has the potential to protect and improve health conditions for both type 1 and type 2 diabetes patients.

PMID:  Nutr Metab (Lond). 2019 ;16:34. Epub 2019 May 22. PMID: 31139236 Abstract Title:  Whole blueberry protects pancreatic beta-cells in diet-induced obese mouse. Abstract:  Background: Blueberry is rich in bioactive substances and possesses powerful antioxidant potential, which can protect against oxidant-induced and inflammatory cell damage and cytotoxicity. The aim of this study was to determine …

Protective functions of Lycium barbarum polysaccharides in H2O2-injured vascular endothelial cells.

PMID:  Biomed Rep. 2019 Nov ;11(5):207-214. Epub 2019 Sep 10. PMID: 31632668 Abstract Title:  Protective functions of Lycium barbarum polysaccharides in HO-injured vascular endothelial cells through anti-oxidation and anti-apoptosis effects. Abstract:  Cell injury in the cardiovascular endothelia caused by oxidative stress is among the major inducers of endothelium dysfunction and serves an important role in …

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