PMID: PLoS One. 2019 ;14(10):e0224495. Epub 2019 Oct 25. PMID: 31652284 Abstract Title: Antibacterial activity of varying UMF-graded Manuka honeys. Abstract: Honey has been used as a traditional remedy for skin and soft tissue infections due to its ability to promote wound healing. Manuka honey is recognized for its unusually abundant content of the antibacterial …
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PMID: J Pharmacol Exp Ther. 2019 Nov ;371(2):360-374. Epub 2019 Aug 16. PMID: 31420528 Abstract Title: Withaferin A Improves Nonalcoholic Steatohepatitis in Mice. Abstract: Nonalcoholic steatohepatitis (NASH) is the progressive stage of nonalcoholic fatty liver disease that highly increases the risk of cirrhosis and liver cancer, and there are few therapeutic options available in the …
Continue reading “Withaferin A improves nonalcoholic steatohepatitis in mice.”
PMID: BMC Complement Altern Med. 2019 Aug 15 ;19(1):217. Epub 2019 Aug 15. PMID: 31416451 Abstract Title: Withania somnifera (L.) Dunal ameliorates neurodegeneration and cognitive impairments associated with systemic inflammation. Abstract: BACKGROUND: Systemic inflammation driven neuroinflammation is an event which correlates with pathogenesis of several neurodegenerative diseases. Therefore, targeting peripheral and central inflammation simultaneously could …
PMID: J Pak Med Assoc. 2019 Oct ;69(10):1479-1485. PMID: 31622301 Abstract Title: Anti-oxidative and anti-proliferative activities of extracted phytochemical compound thymoquinone. Abstract: OBJECTIVE: To evaluate the anti-oxidant and anti-proliferative potential of Thymoquinone extracted from the essential oil of indigenous herbs of Nigella sativa and Thymus vulgaris.METHODS: Extraction and quantification of Thymoquinone was carried out in …
PMID: Int J Radiat Biol. 2019 Oct 22:1-28. Epub 2019 Oct 22. PMID: 31638880 Abstract Title: Nigella sativa oil and Thymoquinone reduce oxidative stress in the brain tissue of rats exposed to full head irradiation. Abstract: To evaluate the antioxidant and radio-protective effects of Nigella sativa oil (NSO) and thymoquinone (TQ) on radiation-induced oxidative stress …
PMID: J Pharmacopuncture. 2019 Sep ;22(3):176-183. Epub 2019 Sep 30. PMID: 31673449 Abstract Title: Induction of Apoptosis and Growth-Inhibition by Thymoquinone in ACHN and GP-293 Cell Lines in Comparable with Cis-Platinum. Abstract: Objective: In the current work, we investigated the cytotoxic and apoptotic effects of Thymoquinone (TQ), an active compound of Nigella sativa (N. sativa) …
PMID: J Environ Pathol Toxicol Oncol. 2019 ;38(2):185-194. PMID: 31679281 Abstract Title: AgNPs from Nigella sativa Control Breast Cancer: An In Vitro Study. Abstract: In our current study, we synthesized silver nanoparticles (AgNPs) from an aqueous seed extract of Nigella sativa. The seed extract contains phytochemical compounds including phenols, terpenoids, and flavonoids that may act …
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PMID: J Nucl Med. 2019 Nov 1. Epub 2019 Nov 1. PMID: 31676729 Abstract Title: Rapid Brain Nicotine Uptake from Electronic Cigarettes. Abstract: This study sought to determine brain nicotine kinetics from the use of increasingly popular electronic cigarettes (E-cigs).Brain uptake of nicotine following inhalation from E-cigs was directly assessed in 17 E-cig users (8 …
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PMID: Phytomedicine. 2019 Sep 16 ;65:153091. Epub 2019 Sep 16. PMID: 31654988 Abstract Title: Total Glucosides of Paeony protects against collagen-induced mouse arthritis via inhibiting follicular helper T cell differentiation. Abstract: BACKGROUND: The development of rheumatoid arthritis (RA) is related to germinal center (GC) response and autoreactive T cells, which mediate adaptive immunity and play …
PMID: J Ethnopharmacol. 2019 Jun 12 ;237:74-80. Epub 2019 Mar 21. PMID: 30904702 Abstract Title: Preclinical investigation of the cardiovascular actions induced by aqueous extract of Pimpinella anisum L. seeds in rats. Abstract: ETHNOPHARMACOLOGY RELEVANCE: Pimpinella anisum is used in traditional medicine because of its pharmacological properties which include cardiovascular action. However, no scientific information …
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