PMID: Nutr Metab (Lond). 2018 ;15:86. Epub 2018 Dec 5. PMID: 30555521 Abstract Title: Amelioration of hepatic steatosis is associated with modulation of gut microbiota and suppression of hepatic miR-34a in(Thunb.) Makino treated mice. Abstract: Background: Non-alcoholic fatty liver disease (NAFLD) is a chronic and progressive liver disease with an increased risk of morbidity and mortality. …
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Inhibitory effect of damulin B from gynostemma pentaphyllum on human lung cancer cells.
PMID: Planta Med. 2019 Mar ;85(5):394-405. Epub 2018 Dec 18. PMID: 30562828 Abstract Title: Inhibitory Effect of Damulin B from Gynostemma pentaphyllum on Human Lung Cancer Cells. Abstract: Damulin B, a dammarane-type saponin from steamed, exhibits the strongest activity against human lung carcinoma A549 cells among the isolated active saponins. In this study, the structure-activity …
Anti-diabetic activity evaluation of a polysaccharide extracted from Gynostemma pentaphyllum.
PMID: Int J Biol Macromol. 2019 Apr 1 ;126:209-214. Epub 2018 Dec 24. PMID: 30590141 Abstract Title: Anti-diabetic activity evaluation of a polysaccharide extracted from Gynostemma pentaphyllum. Abstract: In current study, a polysaccharide (GPP) was successfully extracted from Gynostemma pentaphyllum herb. Monosaccharide composition of GPP was rhamnose, arabinose, galactose, glucose, xylose, mannose, galacturonic acid and …
Supplementation with extract of Gynostemma pentaphyllum leaves reduces anxiety in healthy subjects with chronic psychological stress.
PMID: Phytomedicine. 2019 Jan ;52:198-205. Epub 2018 May 8. PMID: 30599899 Abstract Title: Supplementation with extract of Gynostemma pentaphyllum leaves reduces anxiety in healthy subjects with chronic psychological stress: A randomized, double-blind, placebo-controlled clinical trial. Abstract: BACKGROUND: The ethanol extract of Gynostemma pentaphyllum Makino leaves (EGP) has been reported recently to have anxiolytic effects on …
Immunomodulatory effects of an acidic polysaccharide fraction from herbal Gynostemma pentaphyllum tea in RAW264.7 cells.
PMID: Food Funct. 2019 Apr 1 ;10(4):2186-2197. Epub 2019 Apr 3. PMID: 30942219 Abstract Title: Immunomodulatory effects of an acidic polysaccharide fraction from herbal Gynostemma pentaphyllum tea in RAW264.7 cells. Abstract: A new acidic polysaccharide (GPTP-3) with a molecular weight of 2.49× 10Da was extracted and purified from Gynostemma pentaphyllum tea. Monosaccharide analysis revealed that …
Ethanol extract from Gynostemma pentaphyllum ameliorates dopaminergic neuronal cell death in transgenic mice.
PMID: Neural Regen Res. 2020 Feb ;15(2):361-368. PMID: 31552910 Abstract Title: Ethanol extract fromameliorates dopaminergic neuronal cell death in transgenic mice expressing mutant A53T human alpha-synuclein. Abstract: Gynostemma (G.) pentaphyllum (Cucurbitaceae) contains various bioactive gypenosides. Ethanol extract from G. pentaphyllum (GP-EX) has been shown to have ameliorative effects on the death of dopaminergic neurons in …
Gynostemma Pentaphyllum extract ameliorates high-fat diet-induced obesity.
PMID: Nutrients. 2019 Oct 15 ;11(10). Epub 2019 Oct 15. PMID: 31618980 Abstract Title: Extract Ameliorates High-Fat Diet-Induced Obesity in C57BL/6N Mice by Upregulating SIRT1. Abstract: is widely used in Asia as a herbal medicine to treat type 2 diabetes, dyslipidemia, and inflammation. Here, we investigated the anti-obesity effect and underlying mechanism ofextract (GPE) enriched …
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Red ginseng reduces the inflammatory responses.
PMID: Am J Chin Med. 2019 Oct 23:1-21. Epub 2019 Oct 23. PMID: 31645122 Abstract Title: Red Ginseng Reduces Inflammatory Response via Suppression MAPK/P38 Signaling and p65 Nuclear Proteins Translocation in Rats and Raw 264.7 Macrophage. Abstract: Lipopolysaccharides (LPS) cause systemic inflammatory responses, which are characterized by high mortality and multiple signs, including metabolic disturbances, …
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Ginseng and heme oxygenase-1: The link between an old herb and a new protective system.
PMID: Fitoterapia. 2019 Oct 17 ;139:104370. Epub 2019 Oct 17. PMID: 31629872 Abstract Title: Ginseng and heme oxygenase-1: The link between an old herb and a new protective system. Abstract: Ginseng is an ancient herb, belonging to Asian traditional medicine, that has been considered as a restorative to enhance vitality for centuries. It has been …
Ginsenoside Rb1 alleviates ox-LDL-induced vascular endothelium senescence via the SIRT1/Beclin-1/autophagy axis.
n/a PMID: J Cardiovasc Pharmacol. 2019 Oct 25. Epub 2019 Oct 25. PMID: 31658172 Abstract Title: Ginsenoside Rb1 alleviates ox-LDL-induced vascular endothelium senescence via the SIRT1/Beclin-1/autophagy axis. Abstract: Oxidative low-density lipoprotein (ox-LDL) induces endothelium senescence and promotes atherosclerosis. Ginsenoside Rb1 (gRb1) has been proved to protect HUVECs, but its effect on ox-LDL induced endothelium senescence …
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