PMID: Obstet Gynecol Sci. 2019 Jul ;62(4):242-248. Epub 2019 Jun 19. PMID: 31338341 Abstract Title: Effect of quercetin on the anti-tumor activity of cisplatin in EMT6 breast tumor-bearing mice. Abstract: Objective: The purpose of this study was to determine the effect of quercetin on the antitumor activity of cisplatin and its side-effects.Methods: EMT6 cells, a …
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Quercetin-induced miR-369-3p regulates the inflammatory cascade in chronic inflammatory response and present promising therapeutic implications.
PMID: Mol Nutr Food Res. 2019 Oct ;63(19):e1801390. Epub 2019 Jul 31. PMID: 31338984 Abstract Title: Quercetin-Induced miR-369-3p Suppresses Chronic Inflammatory Response Targeting C/EBP-β. Abstract: SCOPE: Dendritic cells (DCs) are the most potent antigen-presenting cells that play an important role in the crosstalk between the innate and the adaptive immune response. Quercetin exposure is identified …
Nanoencapsulated quercetin improves cardioprotection during hypoxia-reoxygenation injury.
PMID: Oxid Med Cell Longev. 2019 ;2019:7683051. Epub 2019 Jun 24. PMID: 31341535 Abstract Title: Nanoencapsulated Quercetin Improves Cardioprotection during Hypoxia-Reoxygenation Injury through Preservation of Mitochondrial Function. Abstract: The effective delivery of antioxidants to the cells is hindered by their high metabolization rate. In this work, quercetin was encapsulated in poly(lactic-co-glycolic) acid (PLGA) nanoparticles. They …
Perinatal bisphenol A exposure and reprogramming of imprinted gene expression in the adult mouse brain.
PMID: Front Genet. 2019 ;10:951. Epub 2019 Oct 10. PMID: 31649729 Abstract Title: Perinatal Bisphenol A Exposure and Reprogramming of Imprinted Gene Expression in the Adult Mouse Brain. Abstract: Genomic imprinting, a phenomenon by which genes are expressed in a monoallelic, parent-of-origin-dependent fashion, is critical for normal brain development. Expression of imprinted genes is regulatedepigenetic …
Eriodictyol and naringenin can inhibit the formation of advanced glycation end products.
PMID: J Mol Recognit. 2019 Oct 21:e2814. Epub 2019 Oct 21. PMID: 31637788 Abstract Title: Eriodictyol and naringenin inhibit the formation of AGEs: An in vitro and molecular interaction study. Abstract: Maillard reaction occurs between the carbonyl group of reducing sugars and the free amino groups of protein, which eventually results in the formation and …
Structural alterations in DNA by BPA, generate neo-epitopes that may be a factor responsible for the induction of anti-DNA autoantibodies in SLE.
PMID: Autoimmunity. 2019 Oct 26:1-9. Epub 2019 Oct 26. PMID: 31656085 Abstract Title: Bisphenol A modified DNA: A possible immunogenic stimulus for anti-DNA autoantibodies in systemic lupus erythematosus. Abstract: Anti-DNA antibodies are now considered as a universal diagnostic feature for the patients with systemic lupus erythematosus (SLE) but the mechanism(s) involved in the generation of …
Naringenin attenuates the progression of liver fibrosis via inactivation of hepatic stellate cells and profibrogenic pathways.
PMID: Eur J Pharmacol. 2019 Oct 13 ;865:172730. Epub 2019 Oct 13. PMID: 31618621 Abstract Title: Naringenin attenuates the progression of liver fibrosis via inactivation of hepatic stellate cells and profibrogenic pathways. Abstract: There is no effective treatment for hepatic fibrosis. Previously, we demonstrated that naringenin possesses the ability to prevent experimental chronic liver damage. …
Naringenin increases insulin sensitivity and metabolic rate.
PMID: J Med Food. 2019 Oct 31. Epub 2019 Oct 31. PMID: 31670603 Abstract Title: Naringenin Increases Insulin Sensitivity and Metabolic Rate: A Case Study. Abstract: Our studies in primary human adipocytes show that naringenin, a citrus flavonoid, increases oxygen consumption rate and gene expression of uncoupling protein 1 (UCP1), glucose transporter type 4, and …
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Mangosteen is a functional food that could help in lowering the postprandial glucose absorption.
PMID: J Food Biochem. 2019 May ;43(5):e12844. Epub 2019 Mar 21. PMID: 31353530 Abstract Title: α-Amylase inhibition of xanthones from Garcinia mangostana pericarps and their possible use for the treatment of diabetes with molecular docking studies. Abstract: Chromatographic separation of the methanol extract of Garcinia mangostana (mangosteen, Guttiferae) dried pericarps led to the isolation and …
Abnormal lipid metabolism in the liver of developmental rats could be exacerbated by combined exposed to fructose and BPA.
PMID: Int J Environ Res Public Health. 2019 Oct 28 ;16(21). Epub 2019 Oct 28. PMID: 31661889 Abstract Title: Combined Exposure to Fructose and Bisphenol A Exacerbates Abnormal Lipid Metabolism in Liver of Developmental Male Rats. Abstract: The aim of this study was to investigate whether combined exposure to fructose and bisphenol A (BPA) has …
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