Immunotoxic potential of bisphenol F mediated through lipid signaling pathways on macrophages.

PMID:  Environ Sci Technol. 2019 Oct 1 ;53(19):11420-11428. Epub 2019 Sep 16. PMID: 31453682 Abstract Title:  Immunotoxic Potential of Bisphenol F Mediated through Lipid Signaling Pathways on Macrophages. Abstract:  As a bisphenol A (BPA) alternative, bisphenol F (BPF) has been detected in various products, such as paper products, personal care products, and food. More importantly, …

Early prenatal exposure to suspected endocrine disruptor mixtures is associated with lower IQ at age seven.

PMID:  Environ Int. 2019 Oct 19:105185. Epub 2019 Oct 19. PMID: 31668669 Abstract Title:  Early prenatal exposure to suspected endocrine disruptor mixtures is associated with lower IQ at age seven. Abstract:  BACKGROUND: Endocrine disrupting chemicals (EDCs) are xenobiotics with the ability to interfere with hormone action, even at low levels. Prior environmental epidemiology studies link …

This study shows positive associations between exposure to BPA and BPS and the incidence of type 2 diabetes.

PMID:  Environ Health Perspect. 2019 Oct ;127(10):107013. Epub 2019 Oct 30. PMID: 31663775 Abstract Title:  Exposure to Bisphenol A and Bisphenol S and Incident Type 2 Diabetes: A Case-Cohort Study in the French Cohort D.E.S.I.R. Abstract:  BACKGROUND: The question of whether exposure to bisphenol A (BPA) contributes to the development of type 2 diabetes is …

Bisphenol S triggers the malignancy of hemangioma cells via regulation of basic fibroblast growth factor.

PMID:  Chem Biol Interact. 2019 Oct 24:108866. Epub 2019 Oct 24. PMID: 31669319 Abstract Title:  Bisphenol S triggers the malignancy of hemangioma cells via regulation of basic fibroblast growth factor. Abstract:  Hemangioma (IHA) is the most common benign tumor in infants caused by hyperproliferation of mesoblastic vascular tissues. Studies indicated that estrogenic signals have positive …

Cannabidiol directly targets mitochondria and disturbs calcium homeostasis in acute lymphoblastic leukemia.

PMID:  Cell Death Dis. 2019 Oct 14 ;10(10):779. Epub 2019 Oct 14. PMID: 31611561 Abstract Title:  Cannabidiol directly targets mitochondria and disturbs calcium homeostasis in acute lymphoblastic leukemia. Abstract:  Anticancer properties of non-psychoactive cannabinoid cannabidiol (CBD) have been demonstrated on tumors of different histogenesis. Different molecular targets for CBD were proposed, including cannabinoid receptors and …

Cannabidiol can be useful in the management of oral inflammatory disorders.

PMID:  Altern Ther Health Med. 2019 Oct 1. Epub 2019 Oct 1. PMID: 31634872 Abstract Title:  Cannabidiol As A Novel Therapeutic Strategy For Oral Inflammatory Diseases: A Review Of Current Knowledge And Future Perspectives. Abstract:  The high frequency and painful profile of inflammatory oral lesions and the lack of an effective drug protocol for their …

Cannabidiol and cannabinoid compounds as potential strategies for treating Parkinson’s disease.

PMID:  Neurotox Res. 2019 Oct 22. Epub 2019 Oct 22. PMID: 31637586 Abstract Title:  Cannabidiol and Cannabinoid Compounds as Potential Strategies for Treating Parkinson's Disease and L-DOPA-Induced Dyskinesia. Abstract:  Parkinson's disease (PD) and L-DOPA-induced dyskinesia (LID) are motor disorders with significant impact on the patient's quality of life. Unfortunately, pharmacological treatments that improve these disorders …

These results also further confirm that CBD may have therapeutic utility in conditions where neuroinflammatory processes are prominent.

PMID:  Glia. 2019 Oct 24. Epub 2019 Oct 24. PMID: 31647138 Abstract Title:  Cannabidiol prevents LPS-induced microglial inflammation by inhibiting ROS/NF-κB-dependent signaling and glucose consumption. Abstract:  We used mouse microglial cells in culture activated by lipopolysaccharide (LPS, 10 ng/ml) to study the anti-inflammatory potential of cannabidiol (CBD), the major nonpsychoactive component of cannabis. Under LPS …

Dyslipidemias are frequently associated with acne patients.

PMID:  J Dermatol. 2015 Mar ;42(3):296-9. Epub 2015 Jan 13. PMID: 25639454 Abstract Title:  Acne patients frequently associated with abnormal plasma lipid profile. Abstract:  This study was designed to investigate the relationship between plasma lipid profile and acne. Acne patients (n = 181) and healthy volunteers (n = 130) matched in terms of both age …

Total cholesterol, LDL-C, testosterone, and progesterone are higher in acne patients when compared to age-matched controls.

PMID:  Clin Lab. 2014 ;60(7):1201-5. PMID: 25134390 Abstract Title:  Serum lipid profile in female patients with severe acne vulgaris. Abstract:  BACKGROUND: Acne vulgaris is one of the most common skin conditions affecting young adults. The relationship between lipid profile or lipid ratios and acne is not widely reported.METHODS: A case control study was performed in …

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