Ganoderma lucidum extract reduces the motility of breast cancer cells mediated by the RAC lamellipodin axis.

PMID:  Nutrients. 2019 May 19 ;11(5). Epub 2019 May 19. PMID: 31109134 Abstract Title:  Extract Reduces the Motility of Breast Cancer Cells Mediated by the RAC⁻Lamellipodin Axis. Abstract:  Breast cancer (BC) is the second leading cause of cancer death among women worldwide. The main cause of BC morbidity and mortality is the invasiveness capacity of …

Autophagic flux disruption contributes to Ganoderma lucidum polysaccharide-induced apoptosis in human colorectal cancer cells via MAPK/ERK activation.

PMID:  Cell Death Dis. 2019 Jun 11 ;10(6):456. Epub 2019 Jun 11. PMID: 31186406 Abstract Title:  Autophagic flux disruption contributes to Ganoderma lucidum polysaccharide-induced apoptosis in human colorectal cancer cells via MAPK/ERK activation. Abstract:  Targeting autophagy may serve as a promising strategy for cancer therapy. Ganoderma lucidum polysaccharide (GLP) has been shown to exert promising …

Protective effects of Ganoderma lucidum triterpenoids on oxidative stress and apoptosis induced by cadmium.

PMID:  Environ Sci Pollut Res Int. 2019 Aug ;26(23):23967-23980. Epub 2019 Jun 20. PMID: 31222655 Abstract Title:  Protective effects of Ganoderma lucidum triterpenoids on oxidative stress and apoptosis in the spleen of chickens induced by cadmium. Abstract:  Cadmium (Cd) is a heavy metal that poses a huge potential threat to human and animal health. Therefore, …

Antitumor activity of enzymatically hydrolyzed Ganoderma lucidum polysaccharide on U14 cervical carcinoma-bearing mice.

PMID:  Int J Immunopathol Pharmacol. 2019 Jan-Dec;33:2058738419869489. PMID: 31462112 Abstract Title:  Antitumor activity of enzymatically hydrolyzedpolysaccharide on U14 cervical carcinoma-bearing mice. Abstract:  Polysaccharides fromhave been demonstrated to possess diverse biological activities. Despite lots of studies on the biological activities ofpolysaccharide (GLP), little is known regarding the medicinal potential of low-molecular weight enzymatically hydrolyzedpolysaccharide (EGLP). EGLP …

The possible role of PD-1 protein in Ganoderma lucidum-mediated immunomodulation and cancer treatment.

PMID:  Integr Cancer Ther. 2019 Jan-Dec;18:1534735419880275. PMID: 31595795 Abstract Title:  The Possible Role of PD-1 Protein in-Mediated Immunomodulation and Cancer Treatment. Abstract:  has been used in Chinese medicine for thousands years to improve health and to promote longevity. One important function ofis to modulate the immune system. However, the underlying mechanism is not well understood. …

Ganoderma Lucidum induces oxidative DNA damage and enhances the effect of 5-Fluorouracil in colorectal cancer.

PMID:  Mutat Res. 2019 Sep ;845:403065. Epub 2019 Jun 3. PMID: 31561886 Abstract Title:  Ganoderma Lucidum induces oxidative DNA damage and enhances the effect of 5-Fluorouracil in colorectal cancer in vitro and in vivo. Abstract:  The first-line chemotherapy of colorectal cancer (CRC), besides surgery, comprises administration of 5-Fluorouracil (5FU). Apart from cytotoxic effect on cancer …

The identification of active compounds in Ganoderma lucidum var. antler extract inhibiting dengue virus serine protease and its computational studies.

PMID:  J Biomol Struct Dyn. 2019 Oct 24:1-16. Epub 2019 Oct 24. PMID: 31595837 Abstract Title:  The identification of active compounds inextract inhibiting dengue virus serine protease and its computational studies. Abstract:  The number of global dengue incidences is alarmingly high in recent years. The global distribution of four dengue serotypes has also added economic …

Ganoderma lucidum spore oil induces apoptosis of breast cancer cells in vitro and in vivo

PMID:  J Ethnopharmacol. 2020 Jan 30 ;247:112256. Epub 2019 Oct 3. PMID: 31586690 Abstract Title:  Ganoderma lucidum spore oil induces apoptosis of breast cancer cells in vitro and in vivo by activating caspase-3 and caspase-9. Abstract:  ETHNOPHARMACOLOGICAL RELEVANCE: The mushroom Ganoderma lucidum (G. lucidum) is a traditional Chinese medicine reported to have a variety of …

Polysaccharide peptide (PsP) Ganoderma lucidum: a potential inducer for vascular repair in type 2 diabetes mellitus model.

PMID:  Vasc Health Risk Manag. 2019 ;15:419-427. Epub 2019 Oct 3. PMID: 31632046 Abstract Title:  Polysaccharide peptide (PsP) G: a potential inducer for vascular repair in type 2 diabetes mellitus model. Abstract:  Introduction: The increasing blood glucose level due to insulin resistance which occurs in diabetes mellitus (DM) may cause vascular damage. This study aims …

Quercetin synergistically inhibit Epstein-Barr virus-associated gastric carcinoma with Ganoderma lucidum extracts.

PMID:  Molecules. 2019 Oct 24 ;24(21). Epub 2019 Oct 24. PMID: 31653035 Abstract Title:  Quercetin Synergistically Inhibit EBV-Associated Gastric Carcinoma withExtracts. Abstract:  Mycotherapy has been shown to improve the overall response rate during cancer treatment and reduce some chemotherapy-related adverse events.is a traditional mushroom used for pharmaceutical purposes.extracts (GLE) showed potential antitumor activities against several …

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