β-sitosterol mitigates the progression of high-fructose diet-induced non-alcoholic fatty liver disease.

PMID:  Can J Physiol Pharmacol. 2019 Sep 27. Epub 2019 Sep 27. PMID: 31560861 Abstract Title:  β-sitosterol mitigates the progression of high-fructose diet-induced non-alcoholic fatty liver disease in growing male Sprague-Dawley rats. Abstract:  Fructose contributes to the development of non-alcoholic fatty liver disease (NAFLD).β-sitosterol (Bst), a naturally occurring phytosterol, has antihyperlipidaemic and hepatoprotective properties. This …

Anti-obesity effect of Lactobacillus rhamnosus LS-8 and Lactobacillus crustorum MN047 on high-fat and high-fructose diet.

PMID:  Eur J Nutr. 2019 Oct 28. Epub 2019 Oct 28. PMID: 31659451 Abstract Title:  Anti-obesity effect of Lactobacillus rhamnosus LS-8 and Lactobacillus crustorum MN047 on high-fat and high-fructose diet mice base on inflammatory response alleviation and gut microbiota regulation. Abstract:  PURPOSE: The objective of the study was to evaluate the anti-obesity effect of Lactobacillus …

These results indicate that quercetin inhibited the growth of A375SM melanoma cells through apoptosis.

PMID:  Eur J Pharmacol. 2019 Oct 5 ;860:172568. Epub 2019 Jul 23. PMID: 31348906 Abstract Title:  Antitumor and apoptotic effects of quercetin on human melanoma cells involving JNK/P38 MAPK signaling activation. Abstract:  In this study, we investigated whether Quercetin has anti-cancer effects on A375SM and A375P human melanoma cells. Cell viability was assessed using an …

Quercetin protects human granulosa cells against oxidative stress via thioredoxin system.

PMID:  Reprod Biol. 2019 Sep ;19(3):245-254. Epub 2019 Aug 3. PMID: 31383475 Abstract Title:  Quercetin protects human granulosa cells against oxidative stress via thioredoxin system. Abstract:  Granulosa Cells (GCs) are sensitive to excessive production of reactive oxygen species (ROS). Quercetin (QUR) is a free radical scavenger which can alleviate oxidative stress through nuclear factor (erythroid-derived …

These findings suggested that quercetin might be a potentially effective treatment of T2DM-induced NAFLD.

PMID:  Phytother Res. 2019 Aug 26. Epub 2019 Aug 26. PMID: 31452288 Abstract Title:  Quercetin improves nonalcoholic fatty liver by ameliorating inflammation, oxidative stress, and lipid metabolism in db/db mice. Abstract:  Multiphase pathological processes involve in Type 2 diabetes (T2DM)-induced nonalcoholic fatty liver disease (NAFLD). However, the therapies are quite limited. In the present study, …

Anti-angiogenic effects of mangiferin and mechanism of action in metastatic melanoma.

PMID:  Melanoma Res. 2019 Oct 22. Epub 2019 Oct 22. PMID: 31651714 Abstract Title:  Anti-angiogenic effects of mangiferin and mechanism of action in metastatic melanoma. Abstract:  Advanced metastatic melanoma, one of the most aggressive skin malignancies, is currently without reliable therapy. The process of angiogenesis is crucial for progression and metastasis of the majority of …

A single dose of mango leaf extract in combination with quercetin enhances peak power output during repeated sprint exercise.

PMID:  Nutrients. 2019 Oct 28 ;11(11). Epub 2019 Oct 28. PMID: 31661850 Abstract Title:  A Single Dose of The Mango Leaf Extract Zynamitein Combination with Quercetin Enhances Peak Power Output During Repeated Sprint Exercise in Men and Women. Abstract:  The mango leaf extract rich in mangiferin Zynamiteimproves exercise performance when combined with luteolin or quercetin …

Quercetin enhances the anti-tumor effects of BET inhibitors by suppressing hnRNPA1.

PMID:  Int J Mol Sci. 2019 Sep 2 ;20(17). Epub 2019 Sep 2. PMID: 31480735 Abstract Title:  Quercetin Enhances the Anti-Tumor Effects of BET Inhibitors by Suppressing hnRNPA1. Abstract:  Bromodomain and extraterminal domain (BET) proteins, which are important epigenetic readers, are often dysregulated in cancer. While a number of BET inhibitors are currently in early …

These results demonstrated that allicin exerted anti-inflammatory effects against S. aureus mastitis.

PMID:  J Agric Food Chem. 2019 Oct 2 ;67(39):10863-10870. Epub 2019 Sep 19. PMID: 31507180 Abstract Title:  Allicin Inhibited-Induced Mastitis by Reducing Lipid Raft Stability via LxRα in Mice. Abstract:  Mastitis, inflammation of the mammary gland, occurs in both humans and animals.is the most common infectious bacterial pathogen associated with mastitis. We investigated the effects …

Allicin as an add-on therapy improves H. pylori eradication, healing of ulcers, and remission of symptoms.

PMID:  World J Gastroenterol. 2019 Oct 21 ;25(39):6025-6040. PMID: 31660038 Abstract Title:  Allicin as add-on therapy forinfection: A systematic review and meta-analysis. Abstract:  BACKGROUND: Allicin (2-propene-1-sulfinothioic acid S-2-propenyl ester, diallyl thiosulfinate) extracted from garlic, has proven activity against() infection. In recent years, clinical trials have explored its utility as an add-on therapy with variable outcomes …

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