PMID: J Photochem Photobiol B. 2019 May ;194:84-95. Epub 2019 Mar 21. PMID: 30933875 Abstract Title: Apigenin restores impairment of autophagy and downregulation of unfolded protein response regulatory proteins in keratinocytes exposed to ultraviolet B radiation. Abstract: Ultraviolet (UV)-B radiation is a major environmental risk factor that is responsible for the development and progression of …
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PMID: Phytother Res. 2019 Aug 30. Epub 2019 Aug 30. PMID: 31468624 Abstract Title: Apigenin from Croton betulaster Müll restores the immune profile of microglia against glioma cells. Abstract: The flavonoid apigenin, extracted from the Brazilian plant Croton betulaster Müll. has demonstrated the ability to inhibit proliferation, induce differentiation, and modify the inflammatory profile of …
PMID: Cancer Genomics Proteomics. 2019 Nov-Dec;16(6):421-431. PMID: 31659097 Abstract Title: Whole Transcriptomic Analysis of Apigenin on TNFα Immuno-activated MDA-MB-231 Breast Cancer Cells. Abstract: BACKGROUND: Triple-negative breast cancer is categorized by a lack of hormone receptors, inefficacy of anti-estrogen or aromatase inhibitor chemotherapies and greater mortality rates in African American populations. Advanced-stage breast tumors have a …
PMID: Am J Transl Res. 2019 ;11(8):4683-4695. Epub 2019 Aug 15. PMID: 31497191 Abstract Title: Quercetin improves blood-brain barrier dysfunction in rats with cerebral ischemia reperfusion via Wnt signaling pathway. Abstract: Reperfusion therapy after cerebral ischemia often leads to reperfusion injury which may cause brain edema and blood-brain barrier (BBB) dysfunction. As a natural bioflavonoid, …
PMID: Phytother Res. 2019 Sep 9. Epub 2019 Sep 9. PMID: 31497913 Abstract Title: Quercetin protects against cisplatin-induced acute kidney injury by inhibiting Mincle/Syk/NF-κB signaling maintained macrophage inflammation. Abstract: Acute kidney injury (AKI) with high incidence and mortality is the main cause of chronic kidney disease. Previous studies have indicated that quercetin, an abundant flavonoid …
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PMID: J Appl Microbiol. 2019 Sep 11. Epub 2019 Sep 11. PMID: 31509634 Abstract Title: Quercetin reduces atherosclerotic lesions by altering the gut microbiota and reducing atherogenic lipid metabolites. Abstract: AIMS: Epidemiological studies have correlated cardiovascular disease and atherosclerosis with lifestyle factors such as sedentary behaviour and a high-calorie diet. Recent studies of pathogenesis have …
PMID: Int J Mol Med. 2019 Sep ;44(3):893-902. Epub 2019 Jul 3. PMID: 31524223 Abstract Title: Quercetin protects against atherosclerosis by regulating the expression of PCSK9, CD36, PPARγ, LXRα and ABCA1. Abstract: The aim of this study was to investigate the mechanisms through which quercetin protects against atherosclerosis (AS) in apoE‑/‑ mice by regulating the …
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PMID: J Cancer. 2019 ;10(19):4509-4521. Epub 2019 Jul 25. PMID: 31528215 Abstract Title: Combination of quercetin and cisplatin enhances apoptosis in OSCC cells by downregulating xIAP through the NF-κB pathway. Abstract: While cisplatin is a first-line chemotherapeutic drug commonly used to treat patients with oral squamous cell carcinoma (OSCC), the cisplatin-resistance poses a major challenge …
PMID: J Food Sci. 2019 Oct ;84(10):3045-3053. Epub 2019 Sep 17. PMID: 31529802 Abstract Title: Quercetin Mitigates Hepatic Insulin Resistance in Rats with Bile Duct Ligation Through Modulation of the STAT3/SOCS3/IRS1 Signaling Pathway. Abstract: Insulin resistance (IR) and inflammatory mediators are correlated with hepatic fibrosis. Quercetin is a bioflavonoid with well-known antidiabetic and antifibrotic properties. …
Continue reading “This study indicates that quercetin may improve hepatic fibrosis.”
PMID: Biomed Res Int. 2019 ;2019:6282635. Epub 2019 Aug 20. PMID: 31531360 Abstract Title: Quercetin Inhibits Inflammatory Response Induced by LPSin Human Gingival Fibroblasts via Suppressing NF-B Signaling Pathway. Abstract: Quercetin, a natural flavonol existing in many food resources, has been reported to be an effective antimicrobial and anti-inflammatory agent for restricting the inflammation in …
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