PMID: Free Radic Biol Med. 2019 Sep 21 ;145:146-160. Epub 2019 Sep 21. PMID: 31550528 Abstract Title: Quercetin alleviates rat osteoarthritis by inhibiting inflammation and apoptosis of chondrocytes, modulating synovial macrophages polarization to M2 macrophages. Abstract: Osteoarthritis (OA) is a progressive joint disorder that is primarily characterized by the degeneration and destruction of the articular …
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PMID: Pak J Pharm Sci. 2019 May ;32(3 Special):1355-1359. PMID: 31551215 Abstract Title: Quercetin inhibition of myocardial fibrosis through regulating MAPK signaling pathway via ROS. Abstract: Mitogen-activated protein kinase (MAPK) cascades are important players in the cellular signal pathways, and the deregulation of MAPKs is involved in a variety of diseases, especially cardiovascular disorders. This …
PMID: Exp Ther Med. 2019 Oct ;18(4):2451-2458. Epub 2019 Aug 5. PMID: 31555357 Abstract Title: Quercetin has a protective effect on atherosclerosis via enhancement of autophagy in ApoEmice. Abstract: The present study examined the involvement of autophagy as a mechanism in the protective effect of quercetin (QUE) on atherosclerosis (AS) in ApoEmice. An AS model …
PMID: Cancer Med. 2019 Sep 30. Epub 2019 Sep 30. PMID: 31568659 Abstract Title: Quercetin as an innovative therapeutic tool for cancer chemoprevention: Molecular mechanisms and implications in human health. Abstract: Cancer is a life-threatening disease afflicting human health worldwide. Recent advances in drug discovery infrastructure and molecular approaches have helped a lot in identifying …
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PMID: J Food Drug Anal. 2019 Oct ;27(4):887-896. Epub 2019 Aug 21. PMID: 31590760 Abstract Title: Quercetin facilitates cell death and chemosensitivity through RAGE/PI3K/AKT/mTOR axis in human pancreatic cancer cells. Abstract: The triggering of gemcitabine (GEM) drug resistance in pancreatic cancer by the receptor for advanced glycation end products (RAGE) has been demonstrated. Hence, finding …
PMID: Eur J Pharmacol. 2019 Oct 11 ;865:172731. Epub 2019 Oct 11. PMID: 31610186 Abstract Title: Flavonoids reduces lipopolysaccharide-induced release of inflammatory mediators in human bronchial epithelial cells: Structure-activity relationship. Abstract: Flavonoids are polyphenolic compounds that are widely present in food and Chinese medicine. The aim of the present study was to identify the flavonoids …
PMID: Arch Biochem Biophys. 2019 Oct 20:108157. Epub 2019 Oct 20. PMID: 31644887 Abstract Title: Quercetin, but not rutin, attenuated hydrogen peroxide-induced cell damage via heme oxygenase-1 induction in endothelial cells. Abstract: Oxidative stress plays an important role in the pathogenesis of cardiovascular disease. Quercetin, a naturally occurring flavonoid presents in plants and human diet, …
PMID: Int J Mol Sci. 2019 Oct 23 ;20(21). Epub 2019 Oct 23. PMID: 31652815 Abstract Title: Quercetin Directly Targets JAK2 and PKCδ and Prevents UV-Induced Photoaging in Human Skin. Abstract: Quercetin is a naturally occurring polyphenol present in various fruits and vegetables. The bioactive properties of quercetin include anti-oxidative, anti-cancer, anti-inflammatory, and anti-diabetic effects. …
PMID: Mol Genet Metab. 2018 11 ;125(3):305-313. Epub 2018 Aug 10. PMID: 30146452 Abstract Title: Intranasal carnosine attenuates transcriptomic alterations and improves mitochondrial function in the Thy1-aSyn mouse model of Parkinson's disease. Abstract: Mitochondrial dysfunction plays a central role in the pathogenesis of neurodegenerative diseases such as Parkinson's disease (PD). This study was designed to …
PMID: Cancer Cell Int. 2018 ;18:111. Epub 2018 Aug 13. PMID: 30123089 Abstract Title: Carnosine selectively inhibits migration of IDH-wildtype glioblastoma cells in a co-culture model with fibroblasts. Abstract: Background: Glioblastoma (GBM) is a tumor of the central nervous system. After surgical removal and standard therapy, recurrence of tumors is observed within 6-9 months because of …
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