PMID: ACS Med Chem Lett. 2019 Oct 10 ;10(10):1400-1406. Epub 2019 Sep 10. PMID: 31620225 Abstract Title: A Bioreductive Prodrug of Cucurbitacin B Significantly Inhibits Tumor Growth in the 4T1 Xenograft Mice Model. Abstract: Cucurbitacin B (CuB), a highly cytotoxic constituent of the Cucurbitaceae plant, was identified to exhibit potent inhibitory activity against human cancer …
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Acute pancreatitis caused by tamoxifen-induced severe hypertriglyceridemia after 4 years of tamoxifen use.
PMID: ACG Case Rep J. 2019 Feb ;6(2):1-3. Epub 2019 Mar 7. PMID: 31157284 Abstract Title: Acute Pancreatitis Caused by Tamoxifen-Induced Severe Hypertriglyceridemia After 4 Years of Tamoxifen Use. Abstract: We report a case of a 55-year-old woman with hypertension and diabetes mellitus, who took tamoxifen for the past 4 years. She presented with acute …
Tamoxifen-induced acute eosinophilic pneumonia in a breast cancer patient.
PMID: Int J Surg Case Rep. 2019 ;60:186-190. Epub 2019 Feb 27. PMID: 31229774 Abstract Title: Tamoxifen-induced acute eosinophilic pneumonia in a breast cancer patient. Abstract: INTRODUCTION: Tamoxifen is often used as antihormonal therapy in patients with breast cancer. However, it has various side effects, of which pneumonia is a rare occurrence.PRESENTATION OF CASE: A …
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Tamoxifen administration in pregnant mice can be deleterious to both mother and embryo.
PMID: Lab Anim. 2019 Jun 27:23677219856918. Epub 2019 Jun 27. PMID: 31248325 Abstract Title: Tamoxifen administration in pregnant mice can be deleterious to both mother and embryo. Abstract: Since it was introduced 20 years ago, tamoxifen-inducible genetic recombination in vivo has become a standard tool in many fields. This technique has great utility, allowing precise temporal …
Tamoxifen-induced, intestinal-specific deletion of Slc5a6 in adult mice leads to spontaneous inflammation.
PMID: Am J Physiol Gastrointest Liver Physiol. 2019 Oct 1 ;317(4):G518-G530. Epub 2019 Aug 1. PMID: 31369292 Abstract Title: Tamoxifen-induced, intestinal-specific deletion ofin adult mice leads to spontaneous inflammation: involvement of NF-κB, NLRP3, and gut microbiota. Abstract: The sodium-dependent multivitamin transporter (SMVT;) is involved in intestinal absorption of vitamin B7 (biotin). We have previously shown …
Correlation of the tamoxifen use with the increased risk of deep vein thrombosis and pulmonary embolism in elderly women with breast cancer.
PMID: Medicine (Baltimore). 2018 Dec ;97(51):e12842. PMID: 30572423 Abstract Title: Correlation of the tamoxifen use with the increased risk of deep vein thrombosis and pulmonary embolism in elderly women with breast cancer: A case-control study. Abstract: The association between tamoxifen use and risk of deep vein thrombosis or pulmonary embolism in women with breast cancer …
Astragaloside IV attenuates cerebral ischemia and reperfusion injury.
PMID: Sheng Li Xue Bao. 2019 Jun 25 ;71(3):424-430. PMID: 31218333 Abstract Title: [Astragaloside IV attenuates cerebral ischemia and reperfusion injury and reduces activation of NLRP3 inflammasome and NF-κB phosphorylation in rats following a transient middle cerebral artery occlusion]. Abstract: The present study was aimed to investigate the protective effect and anti-inflammation mechanism of astragaloside …
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Acute exposure to static magnetic fields induces oxidative stress while simultaneously upregulating the efficiency of antioxidant enzymes.
PMID: Int J Occup Med Environ Health. 2010 ;23(4):377-84. PMID: 21306983## Abstract Title: Static magnetic field affects oxidative stress in mouse cochlea. Abstract: OBJECTIVE: It has been shown that oxidative stress plays an important role in development of noise induced hearing loss. Since static magnetic fields (SMF) exposure may alter dynamics of oxidative processes in …
Electromagnetic fields induce reactive oxygen species generation and differentiation of human bone marrow derived mesenchymal stem cells through epidermal growth factor receptor in vitro.
PMID: Neurochem Int. 2013 Mar ;62(4):418-24. Epub 2013 Feb 11. PMID: 23411410 Abstract Title: Electromagnetic fields induce neural differentiation of human bone marrow derived mesenchymal stem cells via ROS mediated EGFR activation. Abstract: Even though the inducing effect of electromagnetic fields (EMF) on the neural differentiation of human bone marrow mesenchymal stem cells (hBM-MSCs) is …
Nanosecond pulsed electric field induces the formation of both intra- and extracellular hydrogen peroxide.
PMID: Arch Biochem Biophys. 2012 Nov 1 ;527(1):55-64. Epub 2012 Aug 15. PMID: 22910297 Abstract Title: Oxidative effects of nanosecond pulsed electric field exposure in cells and cell-free media. Abstract: Nanosecond pulsed electric field (nsPEF) is a novel modality for permeabilization of membranous structures and intracellular delivery of xenobiotics. We hypothesized that oxidative effects of …
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