PMID: Brain Res. 1998 Oct 26 ;809(1):50-7. PMID: 9795129 Abstract Title: Evidence for the involvement of nitric oxide and nitric oxide synthase in the modulation of opioid-induced antinociception and the inhibitory effects of exposure to 60-Hz magnetic fields in the land snail. Abstract: The attenuation of opioid peptide-mediated antinociception is a well-established effect of extremely …
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PMID: Adv Clin Exp Med. 2015 Jan-Feb;24(1):31-5. PMID: 25923084 Abstract Title: The impact of electromagnetic radiation of different parameters on platelet oxygen metabolism – in vitro studies. Abstract: BACKGROUND: Electromagnetic radiation emitted by a variety of devices, e.g. cell phones, computers and microwaves, interacts with the human body in many ways. Research studies carried out …
Ever since news of the capabilities of cannabidiol (CBD) traveled from academia to the public, the plant extract has surged into mainstream use and wellness popularity. After years of underground CBD sales and several clinical studies on its growing list of positive effects, the Agriculture Improvement Act of 2018, also known as the Farm Bill, was …
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PMID: Eur J Pharmacol. 2019 Sep 15 ;859:172490. Epub 2019 Jun 21. PMID: 31229536 Abstract Title: Astragaloside IV alleviates doxorubicin induced cardiomyopathy by inhibiting NADPH oxidase derived oxidative stress. Abstract: Doxorubicin (DOX) is a classic anti-tumor chemotherapeutic used to treat a wide range of tumors. One major downfall of DOX treatment is it can induce …
PMID: Exp Anim. 2019 Jun 26. Epub 2019 Jun 26. PMID: 31243190 Abstract Title: Astragaloside IV reduces cardiomyocyte apoptosis in a murine model of coxsackievirus B3-induced viral myocarditis. Abstract: Apoptosis plays a crucial role in regulating cardiomyopathy and injuries of coxsackievirus B3 (CVB3)-induced viral myocarditis (VM). It has been reported that Astragaloside IV (AST-IV) from Astragalus membranaceus could …
PMID: Int J Mol Med. 2019 Sep ;44(3):847-856. Epub 2019 Jun 26. PMID: 31257467 Abstract Title: Astragaloside IV inhibits oxidized low‑density lipoprotein‑induced endothelial damage via upregulation of miR‑140‑3p. Abstract: Oxidized low‑density lipoprotein (ox‑LDL)‑mediated endothelial cell injury has an important role in the vascular complications of type 2 diabetes. Astragaloside IV (ASV) is an active component …
PMID: Oxid Med Cell Longev. 2019 ;2019:4625912. Epub 2019 Jun 11. PMID: 31285785 Abstract Title: Astragaloside IV Exerts a Myocardial Protective Effect against Cardiac Hypertrophy in Rats, Partially via Activating the Nrf2/HO-1 Signaling Pathway. Abstract: Previous evidence suggested that astragaloside IV (ASIV) had a cardioprotective effect, but the potential mechanisms were undetermined. This study is …
PMID: Immunopharmacol Immunotoxicol. 2019 Aug ;41(4):497-503. Epub 2019 Jul 11. PMID: 31293216 Abstract Title: Astragaloside inhibits IL-1β-induced inflammatory response in human osteoarthritis chondrocytes and ameliorates the progression of osteoarthritis in mice. Abstract: Osteoarthritis (OA) is a chronic joint-degeneration disease and accounts for the most frequent arthritis in aging people. OA is characterized by the degeneration …
PMID: J Oral Pathol Med. 2019 Jul 18. Epub 2019 Jul 18. PMID: 31318999 Abstract Title: Astragaloside IV attenuates inflammatory injury and promotes odontoblastic differentiation in lipopolysaccharide-stimulated MDPC-23 cells and rat pulpitis. Abstract: BACKGROUND: Astragaloside IV (AS-IV), a natural herbal compound from Astragalus membranaceus, has inhibitory effects on receptor activator of nuclear factor-κB ligand (RANKL)-induced …
PMID: Oxid Med Cell Longev. 2019 ;2019:9137654. Epub 2019 Jun 24. PMID: 31341538 Abstract Title: Astragaloside IV Attenuates Myocardial Ischemia-Reperfusion Injury from Oxidative Stress by Regulating Succinate, Lysophospholipid Metabolism, and ROS Scavenging System. Abstract: Astragaloside IV is one of the main active ingredients isolated from. Here we confirmed its protective effect against cardiac ischemia-reperfusion (I/R) …
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