PMID: J Complement Integr Med. 2019 Sep 18. Epub 2019 Sep 18. PMID: 31532754 Abstract Title: Crocin treatment decreased pancreatic atrophy, LOX-1 and RAGE mRNA expression of pancreas tissue in cholesterol-fed and streptozotocin-induced diabetic rats. Abstract: Objective Oxidative stress in diabetic mellitus is a consequence of oxidative stress, which plays a critical role in the …
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Apple polyphenol extract alleviates high-fat-diet-induced hepatic steatosis.
PMID: J Agric Food Chem. 2019 Oct 23. Epub 2019 Oct 23. PMID: 31608624 Abstract Title: Apple Polyphenol Extract Alleviates High-Fat-Diet-Induced Hepatic Steatosis in Male C57BL/6 Mice by Targeting LKB1/AMPK Pathway. Abstract: To explore the role of apple polyphenol extract (APE) in ameliorating hepatic steatosis and the potential mechanisms involved, we conducted this study. Thirty-three …
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Combination therapy of vitamin D analogs with corticosteroids might also be used in treating alopecia areata.
PMID: Am J Transl Res. 2019 ;11(9):5285-5300. Epub 2019 Sep 15. PMID: 31632510 Abstract Title: Vitamin D and alopecia areata: possible roles in pathogenesis and potential implications for therapy. Abstract: Alopecia areata is characterized by the loss of hair on the scalp and elsewhere on the body. It affects approximately 2% of the general population. …
This review article provides an account of the latest research on the development of gold compounds and their potential activities against several cancers.
PMID: Molecules. 2018 Jun 11 ;23(6). Epub 2018 Jun 11. PMID: 29891764 Abstract Title: Gold-Based Medicine: A Paradigm Shift in Anti-Cancer Therapy? Abstract: A new era of metal-based drugs started in the 1960s, heralded by the discovery of potent platinum-based complexes, commencing with cisplatin [(H₃N)₂PtCl₂], which are effective anti-cancer chemotherapeutic drugs. While clinical applications of …
These results may suggest inhibition of enzymatic activity by gold.
PMID: Indian J Clin Biochem. 2013 Jul ;28(3):303-4. Epub 2013 Feb 5. PMID: 24426228 Abstract Title: A preliminary study of the effect of ingestion of gold on blood chemistry. Abstract: Ten milligram of pure gold foil was given by mouth for 16 days. Routine blood chemistry was done before and after gold therapy and repeated after …
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Crocin improves cognitive behavior in rats with Alzheimer’s disease.
PMID: Biomed Res Int. 2019 ;2019:9454913. Epub 2019 Aug 26. PMID: 31534969 Abstract Title: Crocin Improves Cognitive Behavior in Rats with Alzheimer's Disease by Regulating Endoplasmic Reticulum Stress and Apoptosis. Abstract: Aim: To investigate the effect of crocin on the learning and memory acquisition of AD rats and its underlying mechanisms.Methods: A total of 48 …
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These results suggest the beneficial and therapeutic effects of crocin in multiple sclerosis.
PMID: J Biochem Mol Toxicol. 2019 Oct 16:e22410. Epub 2019 Oct 16. PMID: 31617649 Abstract Title: Effects of crocin in reducing DNA damage, inflammation, and oxidative stress in multiple sclerosis patients: A double-blind, randomized, and placebo-controlled trial. Abstract: Multiple sclerosis (MS) is an autoimmune disease in which the immune system attacks the nerve cells, resulting …
Regular probiotic yoghurt consumption guarded against exhaustive exercise-inducing oxidative injury in young healthy females.
PMID: J Pak Med Assoc. 2018 Dec ;68(12):1748-1754. PMID: 30504936 Abstract Title: The effect of probiotic yoghurt consumption on oxidative stress and inflammatory factors in young females after exhaustive exercise. Abstract: OBJECTIVE: To evaluate the effect of probiotic yoghurt consumption on oxidative stress and inflammatory factors in young females after exhaustive exercise.METHODS: TThis study included …
Probiotic yogurt consumption during pregnancy was effective in reducing the risk of gestational diabetes mellitus in Chinese women.
PMID: Iran J Public Health. 2019 Jul ;48(7):1248-1256. PMID: 31497545 Abstract Title: Association between Probiotic Yogurt Intake and Gestational Diabetes Mellitus: A Case-Control Study. Abstract: Background: Gestational diabetes mellitus is one of the most frequent metabolic complications of pregnancy. Previous studies have reported that using either probiotic yogurt or a probiotic supplement reduces the incidence …
Heat-killed probiotic regulates the body’s regulatory immunity to attenuate subsequent experimental autoimmune arthritis.
PMID: Immunol Lett. 2019 Oct 20. Epub 2019 Oct 20. PMID: 31644891 Abstract Title: Heat-killed probiotic regulates the body's regulatory immunity to attenuate subsequent experimental autoimmune arthritis. Abstract: Administration of inactivated probiotics has been proved to enhance host immunity. Herein, we aim to explore their potential in modulating systemic autoimmune disorders. The bovine type II …
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