Treatment with α-lipoic acid can prevent cardiac hyperplasia and dysfunction.

PMID:  Heliyon. 2019 Aug ;5(8):e02371. Epub 2019 Aug 28. PMID: 31517099 Abstract Title:  α-Lipoic acid exerts a primary prevention for the cardiac dysfunction in aortocaval fistula-created rat hearts. Abstract:  Aim: α-Lipoic acid exerts a powerful antioxidant effect by acting as a free radical scavenger and inducing endogenous antioxidants such as vitamin E and glutathione. In …

Consumption of alpha-lipoic acid-rich foods may prevent the development of H. pylori-associated gastric diseases.

PMID:  Nutrients. 2019 Oct 19 ;11(10). Epub 2019 Oct 19. PMID: 31635029 Abstract Title:  α-Lipoic Acid Inhibits IL-8 Expression by Activating Nrf2 Signaling in-infected Gastric Epithelial Cells. Abstract:  causes gastritis and gastric cancers. Oxidative stress is involved in the pathological mechanism of-induced gastritis and gastric cancer induction. Therefore, reducing oxidative stress may be beneficial for …

Z. multiflora treatment improved learning and memory impairment as well as lung inflammation and oxidative stress induced by inhaled paraqut.

PMID:  Nutr Neurosci. 2019 Oct 4:1-14. Epub 2019 Oct 4. PMID: 31583983 Abstract Title:  The effect ofhydroalcoholic extract on memory and lung changes induced by rats that inhaled paraquat. Abstract:  The effects of hydroalcoholic extract of() on memory changes, as well as lung injury due to inhaled paraqut (PQ) in rat, were examined.Control group of …

Benzyl isothiocyanate promotes miR-99a expression through ERK/AP-1-dependent pathway in bladder cancer cells.

PMID:  Environ Toxicol. 2019 Oct 6. Epub 2019 Oct 6. PMID: 31587482 Abstract Title:  Benzyl isothiocyanate promotes miR-99a expression through ERK/AP-1-dependent pathway in bladder cancer cells. Abstract:  Benzyl isothiocyanate (BITC), a bioactive natural product present in cruciferous vegetables, has been proved to prevent cancer progression through various mechanisms. In our previous report, we proved that …

Ginsenoside Rh2 suppresses breast cancer cell Proliferation by epigenetically regulating the long noncoding RNA C3orf67-AS1.

PMID:  Am J Chin Med. 2019 Oct 23:1-16. Epub 2019 Oct 23. PMID: 31645124 Abstract Title:  Ginsenoside Rh2 Suppresses Breast Cancer Cell Proliferation by Epigenetically Regulating the Long Noncoding RNA C3orf67-AS1. Abstract:  Ginsenoside Rh2, a major bioactive ingredient abundant in red ginseng, has an antiproliferative effect on various cancer cells. In this study, we report …

Phenethyl isothiocyanate hampers growth and progression of HER2-positive breast and ovarian carcinoma by targeting their stem cell compartment.

PMID:  Cell Oncol (Dordr). 2019 Aug 2. Epub 2019 Aug 2. PMID: 31376137 Abstract Title:  Phenethyl isothiocyanate hampers growth and progression of HER2-positive breast and ovarian carcinoma by targeting their stem cell compartment. Abstract:  PURPOSE: Isothiocyanates elicit anticancer effects by targeting cancer stem cells (CSCs). Here, we tested the antitumor activity of phenethyl-isothiocyanate (PEITC), either …

Phloretin may be a potent reagent for hepatocellular carcinoma treatment.

PMID:  Cell Commun Signal. 2019 Oct 16 ;17(1):127. Epub 2019 Oct 16. PMID: 31619257 Abstract Title:  Phloretin attenuates STAT-3 activity and overcomes sorafenib resistance targeting SHP-1-mediated inhibition of STAT3 and Akt/VEGFR2 pathway in hepatocellular carcinoma. Abstract:  BACKGROUND: Hepatocellular carcinoma (HCC) is the most common primary liver malignancy. Phloretin (PH) possesses anticancer, antitumor, and hepatoprotective effects, …

Malaysian Tualang honey inhibits hydrogen peroxide-Induced endothelial hyperpermeability.

PMID:  Oxid Med Cell Longev. 2019 ;2019:1202676. Epub 2019 Aug 18. PMID: 31531177 Abstract Title:  Malaysian Tualang Honey Inhibits Hydrogen Peroxide-Induced Endothelial Hyperpermeability. Abstract:  Malaysian Tualang honey (TH) is a known therapeutic honey extracted from the honeycombs of the Tualang tree (Koompassia excelsa) and has been reported for its antioxidant, anti-inflammatory, antiproliferative, and wound healing …

Urolithin A significantly attenuated the histopathological hallmarks of cisplatin-induced acute kidney injury and reduced mortality by 63%.

PMID:  Am J Physiol Renal Physiol. 2019 Sep 18. Epub 2019 Sep 18. PMID: 31532243 Abstract Title:  Oral Delivery of Nanoparticle Urolithin A Normalizes Cellular Stress and Improves Survival in Mouse Model of Cisplatin-induced AKI. Abstract:  The popular anti-cancer drug cisplatin causes many adverse side-effects, the most serious of which is acute kidney injury (AKI). …

Isoliquiritigenin may be an effective therapeutic agent against ovarian cancer.

PMID:  Molecules. 2019 Oct 16 ;24(20). Epub 2019 Oct 16. PMID: 31623144 Abstract Title:  Isoliquiritigenin Inhibits Ovarian Cancer Metastasis by Reversing Epithelial-to-Mesenchymal Transition. Abstract:  The epithelial-to-mesenchymal transition (EMT) plays a prominent role in cancer metastasis. Isoliquiritigenin (ISL), one of the flavonoids in licorice, has been shown to exhibit anticancer activities in many cancer types through …

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