PMID: PLoS One. 2015 ;10(3):e0121529. Epub 2015 Mar 26. PMID: 25811625 Abstract Title: Biochanin a gastroprotective effects in ethanol-induced gastric mucosal ulceration in rats. Abstract: BACKGROUND: Biochanin A notable bioactive compound which is found in so many traditional medicinal plant. In vivo study was conducted to assess the protective effect of biochanin A on the …
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Biochanin A ameliorates arsenic-induced hepato- and hematotoxicity in rats.
PMID: Molecules. 2016 Jan 9 ;21(1):69. Epub 2016 Jan 9. PMID: 26760991 Abstract Title: Biochanin A Ameliorates Arsenic-Induced Hepato- and Hematotoxicity in Rats. Abstract: Biochanin A (BCA) is a natural organic compound of the phytoestrogenic isoflavone class that has antioxidant and metal chelator properties in the presence of transition metal ions, however, its efficacy in …
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Biochanin A might raise a possibility as a potential therapeutic agent for Alzheimer’s disease and other related neurodegenerative diseases.
PMID: Molecules. 2016 Apr 25 ;21(5). Epub 2016 Apr 25. PMID: 27120593 Abstract Title: Neuroprotective Effects of Biochanin A againstβ-Amyloid-Induced Neurotoxicity in PC12 Cells via a Mitochondrial-Dependent Apoptosis Pathway. Abstract: Alzheimer's disease is considered one of the major neurodegenerative diseases and is characterized by the production ofβ-amyloid (Aβ) proteins and progressive loss of neurons. Biochanin …
Biochanin A improves hepatic steatosis and insulin resistance by regulating the hepatic lipid and glucose metabolic pathways in diet-induced obesity.
PMID: Mol Nutr Food Res. 2016 09 ;60(9):1944-55. Epub 2016 Jun 8. PMID: 27145114 Abstract Title: Biochanin A improves hepatic steatosis and insulin resistance by regulating the hepatic lipid and glucose metabolic pathways in diet-induced obese mice. Abstract: SCOPE: Natural compounds that regulate peroxisome proliferator-activated receptor alpha (PPARα) have been reported to have beneficial effects …
Biochanin A protects lipopolysaccharide/D-galactosamine-induced acute liver injury.
PMID: Int Immunopharmacol. 2016 Sep ;38:324-31. Epub 2016 Jun 23. PMID: 27344638 Abstract Title: Biochanin A protects lipopolysaccharide/D-galactosamine-induced acute liver injury in mice by activating the Nrf2 pathway and inhibiting NLRP3 inflammasome activation. Abstract: Biochanin A, an isoflavone existed in red clover and peanuts, has been reported to possess a wide spectrum of pharmacological activities, …
Biochanin A exerts protective effects on lipopolysaccharide-induced Parkinson’s disease.
PMID: Neurotox Res. 2016 10 ;30(3):486-98. Epub 2016 Jul 14. PMID: 27417698 Abstract Title: Biochanin A Protects Against Lipopolysaccharide-Induced Damage of Dopaminergic Neurons Both In Vivo and In Vitro via Inhibition of Microglial Activation. Abstract: Neuroinflammation has been reported to be involved in the pathogenesis of Parkinson's disease (PD). Inhibition of microglia-mediated neuroinflammation might be …
(Not a) Surprise: Glyphosate-based Herbicides are Bad for Your Mental Health
Eat your veggies is no longer synonymous with health thanks to the increasingly documented deleterious health effects of chemical pesticides and herbicides
Biochanin-A attenuates neuropathic pain in diabetic rats.
PMID: J Ayurveda Integr Med. 2016 Oct – Dec;7(4):231-237. Epub 2016 Nov 25. PMID: 27890700 Abstract Title: Biochanin-A attenuates neuropathic pain in diabetic rats. Abstract: BACKGROUND: Soya supplements are used in the treatment of neuropathic pain. Previous reports reveal that consumption of soy diet before nerve injury prevents the development of neuropathic pain in rats. …
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Potential lipid-lowering mechanisms of biochanin A.
PMID: J Agric Food Chem. 2017 May 17 ;65(19):3842-3850. Epub 2017 May 4. PMID: 28447802 Abstract Title: Potential Lipid-Lowering Mechanisms of Biochanin A. Abstract: Extensive studies have demonstrated that biochanin A (BCA) has a significant hypolipidemic effect. However, its mechanism of action is not clear. In this context, the effect of BCA on a high-fat …
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Biochanin-A induces apoptosis and suppresses migration in FaDu human pharynx squamous carcinoma cells.
PMID: Oncol Rep. 2017 Nov ;38(5):2985-2992. Epub 2017 Sep 13. PMID: 28901495 Abstract Title: Biochanin-A induces apoptosis and suppresses migration in FaDu human pharynx squamous carcinoma cells. Abstract: The aim of the present study was to investigate biochanin-A-induced anticancer effects and their cellular signaling pathway in FaDu pharyngeal squamous carcinoma cells. Biochanin-A induced cell death …
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