PMID: Int J Radiat Biol. 2004 Apr ;80(4):317-24. PMID: 15204708 Abstract Title: Extremely low frequency magnetic fields and the promotion of H2O2-induced cell death in HL-60 cells. Abstract: PURPOSE: To test whether exposure to an extremely low frequency magnetic field (60 Hz, 5 mT) affects hydrogen peroxide (H2O2)-induced cell death in human leukaemia HL-60 cells.MATERIALS …
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Biochanin A protects against oxidative damage in HepG2 cells.
PMID: Biofactors. 2019 Jul ;45(4):563-574. Epub 2019 May 27. PMID: 31131946 Abstract Title: Isoflavone biochanin A, a novel nuclear factor erythroid 2-related factor 2 (Nrf2)-antioxidant response element activator, protects against oxidative damage in HepG2 cells. Abstract: Isoflavones are one group of the major flavonoids and possess multiple biological activities due to their antioxidant properties. However, …
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Reduced glutathione could play an important role in the antioxidant defense towards the ELF-MF-induced redox challenge.
PMID: J Cell Physiol. 2009 May ;219(2):334-43. PMID: 19115234 Abstract Title: Fifty hertz extremely low-frequency magnetic field exposure elicits redox and trophic response in rat-cortical neurons. Abstract: Large research activity has raised around the mechanisms of interaction between extremely low-frequency magnetic fields (ELF-MFs) and biological systems. ELF-MFs may interfere with chemical reactions involving reactive oxygen …
Biochanin A protects against fine particulate matter-induced acute pulmonary cell injury.
PMID: Food Funct. 2019 Oct 14. Epub 2019 Oct 14. PMID: 31608342 Abstract Title: Biochanin A protects against PM-induced acute pulmonary cell injury by interacting with the target protein MEK5. Abstract: Epidemiological studies have shown that exposure to ambient fine particulate matter (PM2.5) is associated with an increased risk for cardiopulmonary diseases. The MEK5/ERK5 and …
The results of this study indicate that both intermittent and continuous magnetic field exposures affect various tissues in a distinct manner because of having different tissue antioxidant status and responses.
PMID: Neurochem Res. 2009 Feb ;34(2):238-43. Epub 2008 Jun 18. PMID: 18563561 Abstract Title: Effects of continuous and intermittent magnetic fields on oxidative parameters in vivo. Abstract: Continuous and intermittent 50 Hz, 1.5 mT magnetic field with the exposure period of 4 h/day for 4 days was used to investigate its possible effect on adult …
Exposures to extremely low frequency magnetic field induces serious oxidative stress in the hippocampus and striatum and impaired hippocampal-dependent spatial learning and striatum-dependent habit learning in rats.
PMID: PLoS One. 2012 ;7(5):e32196. Epub 2012 May 3. PMID: 22570685 Abstract Title: Deficits in water maze performance and oxidative stress in the hippocampus and striatum induced by extremely low frequency magnetic field exposure. Abstract: The exposures to extremely low frequency magnetic field (ELF-MF) in our environment have dramatically increased. Epidemiological studies suggest that there …
Anti-proliferative activity of biochanin A in human osteosarcoma cells via mitochondrial-involved apoptosis.
PMID: Food Chem Toxicol. 2018 Feb ;112:194-204. Epub 2018 Jan 3. PMID: 29305928 Abstract Title: Anti-proliferative activity of biochanin A in human osteosarcoma cells via mitochondrial-involved apoptosis. Abstract: Biochanin A is a major isoflavone in red clover and a potent chemopreventive agent against cancer. However, the effects of biochanin A on human osteosarcoma cells have …
Potential anticancer properties and mechanisms of action of formononetin.
PMID: Biomed Res Int. 2019 ;2019:5854315. Epub 2019 Jul 28. PMID: 31467899 Abstract Title: Potential Anticancer Properties and Mechanisms of Action of Formononetin. Abstract: Nature, a vast reservoir of pharmacologically active molecules, has been most promising source of drug leads for the cure of various pathological conditions. Formononetin is one of the bioactive isoflavones isolated …
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Focus on formononetin: anticancer potential and molecular targets.
PMID: Cancers (Basel). 2019 May 1 ;11(5). Epub 2019 May 1. PMID: 31052435 Abstract Title: Focus on Formononetin: Anticancer Potential and Molecular Targets. Abstract: Formononetin, an isoflavone, is extracted from various medicinal plants and herbs, including the red clover (and Chinese medicinal plantFormononetin's antioxidant and neuroprotective effects underscore its therapeutic use against Alzheimer's disease. Formononetin …
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Aluminum and ELF-MF may impact on learning memory and potentiate oxidative stress in mice.
PMID: Biol Trace Elem Res. 2013 Dec ;156(1-3):243-52. Epub 2013 Oct 26. PMID: 24158621 Abstract Title: Effects of aluminum and extremely low frequency electromagnetic radiation on oxidative stress and memory in brain of mice. Abstract: This study was aimed to investigate the effect of aluminum and extremely low-frequency magnetic fields (ELF-MF) on oxidative stress and …