PMID: Cancer Lett. 2018 09 1 ;431:123-141. Epub 2018 May 29. PMID: 29857127 Abstract Title: Formononetin-induced oxidative stress abrogates the activation of STAT3/5 signaling axis and suppresses the tumor growth in multiple myeloma preclinical model. Abstract: Aberrant reactions of signal transducer and transcriptional activator (STAT) are frequently detected in multiple myeloma (MM) cancers and can …
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These findings demonstrate a potentially new therapeutic strategy of formononetin as anti-invasive agent for breast cancer.
PMID: Horm Metab Res. 2014 Oct ;46(11):753-60. Epub 2014 Jun 30. PMID: 24977660 Abstract Title: Formononetin inhibits migration and invasion of MDA-MB-231 and 4T1 breast cancer cells by suppressing MMP-2 and MMP-9 through PI3K/AKT signaling pathways. Abstract: Formononetin is a naturally existing isoflavone, which can be found in the roots of Astragalus membranaceus, Trifolium pratense, …
Electromagnetic pulse radiation induces oxidative stress and apoptosis, leading to brain damage in rats.
PMID: PLoS One. 2014 ;9(3):e91019. Epub 2014 Mar 10. PMID: 24614080 Abstract Title: Neuroprotective effects of sevoflurane against electromagnetic pulse-induced brain injury through inhibition of neuronal oxidative stress and apoptosis. Abstract: Electromagnetic pulse (EMP) causes central nervous system damage and neurobehavioral disorders, and sevoflurane protects the brain from ischemic injury. We investigated the effects of …
This is the first report of the presence of potent cyclooxygenase-2 inhibitors in Trifolium pratense L. extracts.
PMID: J Sep Sci. 2019 Mar ;42(6):1133-1143. Epub 2019 Feb 25. PMID: 30620132 Abstract Title: Screening and isolation of cyclooxygenase-2 inhibitors from Trifolium pratense L. via ultrafiltration, enzyme-immobilized magnetic beads, semi-preparative high-performance liquid chromatography and high-speed counter-current chromatography. Abstract: Nonsteroidal anti-inflammatory drugs reportedly reduce the risk of developing cancer. One mechanism by which they reduce …
Extremely low-frequency electromagnetic fields induce oxidative stress in liver rat tissue.
PMID: Cell Biochem Biophys. 2011 Mar ;59(2):71-7. PMID: 20824388 Abstract Title: Oxidative stress and apoptosis in relation to exposure to magnetic field. Abstract: We investigated the effect of extremely low-frequency electromagnetic field (ELF-EMF) with pulse trains exposure on lipid peroxidation, and, hence, oxidative stress in the rat liver tissue. The parameters that we measured were …
Selenium enhanced phytoremediation of diesel in soil by Trifolium repens.
PMID: Ecotoxicol Environ Saf. 2018 Jun 15 ;154:137-144. Epub 2018 Feb 22. PMID: 29459163 Abstract Title: Se enhanced phytoremediation of diesel in soil by Trifolium repens. Abstract: A pot-culture experiment was conducted to assess the effects of selenium (Se) (0.5 mg kg) on Trifolium repens exposed to various levels of diesel (0, 15, 20, 25 g kg) for 30 …
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T. pratense showed anti-cancer properties via induction of apoptosis and autophagy cell death.
PMID: Cell J. 2018 Oct ;20(3):412-421. Epub 2018 May 15. PMID: 29845796 Abstract Title: Evaluation of Hydro-Alcoholic Extract of Trifolium Pratens L. for Its Anti-Cancer Potential on U87MG Cell Line. Abstract: Objective: Glioblastoma multiforme is the most malignant form of brain tumors. Trifolium pratense L. has been suggested for cancer treatment in traditional medicine. Here …
Lotus seedpod procyanidins mitigate the oxidative effects and learning and memory damage caused by extremely low frequency electromagnetic fields on
PMID: Food Funct. 2013 Aug ;4(8):1252-62. PMID: 23764910 Abstract Title: The preventive effect of lotus seedpod procyanidins on cognitive impairment and oxidative damage induced by extremely low frequency electromagnetic field exposure. Abstract: The present study investigated the effects of lotus seedpod procyanidins (LSPCs) administered by oral gavage on the cognitive deficits and oxidative damage of …
T. pratense not only has anti-diabetic actions on β cells but also enhances their viability.
PMID: Res Pharm Sci. 2018 Aug ;13(4):324-331. PMID: 30065765 Abstract Title: Protective effect of hydroalcoholic extracts of. on pancreaticβ cell line (RIN-5F) against cytotoxicty of streptozotocin. Abstract: Natural plants have traditionally been used throughout the world for their anti-diabetic effects. The aim of the present study was to investigate the protective effect of hydroalcoholic extract …
Genetic polymorphisms affect superoxide dismutase activity may potentiate the negative effects of magnetic fields.
PMID: Environ Sci Pollut Res Int. 2017 Feb ;24(5):5078-5088. Epub 2016 Dec 21. PMID: 28004364 Abstract Title: Cytotoxic effects of moderate static magnetic field exposure on human periphery blood mononuclear cells are influenced by Val16Ala-MnSOD gene polymorphism. Abstract: Technological advancement has increasingly exposed humans to magnetic fields (MFs). However, more insights are necessary into the …
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